Cancer

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Cancer

  1. 1. Cancer
  2. 2. What is cancer? <ul><li>Cancer is a general term for a wide range of diseases. </li></ul><ul><li>It is characterized by cells that are aggressive, Invasive, and sometimes metastatic. </li></ul><ul><li>These are malignant properties </li></ul>
  3. 3. Who can get it? <ul><li>Cancer may affect people of all ages. </li></ul><ul><li>Risk tends to increase with age. </li></ul><ul><li>Cancer is responsible for 13% of all deaths. </li></ul>
  4. 4. How does it occur? <ul><li>Nearly all cancers are caused by abnormalities in the genetic material of the transformed cells . </li></ul><ul><li>These mutations could have been caused by exposure to carcinogens. </li></ul><ul><li>Other causes of mutations could be from mistakes in mitosis. </li></ul>
  5. 5. What happens in the DNA? <ul><li>Genetic abnormalities found in cancer typically affect two general classes of genes. </li></ul><ul><li>Cancer-promoting genes are often activated in cancer cells, giving those cells new properties. </li></ul><ul><li>Tumor suppressor genes are often inactivated in cancer cells. </li></ul>
  6. 6. Treatment <ul><li>Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy. </li></ul><ul><li>Chemotherapy is the use of cytotoxic drugs to treat cancer. </li></ul><ul><li>Radiotherapy is the use of radiation to kill cancer cells. </li></ul>
  7. 7. New types of treatment <ul><li>Targeted therapy- PRIT (pretargeted radioimmmunotherapy) </li></ul><ul><li>Targets only the cancer cells, does not attack other body cells. </li></ul><ul><li>Receptors on the cell membrane of the cancer cells will identify it as a cancer cell. </li></ul><ul><li>Another protein can match up with those receptors. </li></ul>
  8. 8. Targeted therapy <ul><li>The protein is tagged with a radionuclide (radioactive atom). </li></ul><ul><li>The protein acts as a vehicle to deliver the radiation only to the cancer cells. </li></ul><ul><li>Using this method we can deliver much higher forms of radiation without worrying about damage to other tissues. </li></ul>
  9. 9. Movies tumor destruction

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