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Eicosanoids- Chemistry and
Functions- A Brief Review




5/20/2012   Biochemistry for Medics   1
Eicosanoids




5/20/2012   Biochemistry for Medics   2
Eicosanoids- Classification




5/20/2012   Biochemistry for Medics   3
Prostanoids




5/20/2012   Biochemistry for Medics   4
Characteristic features of
Structure of prostaglandins




5/20/2012   Biochemistry for Medics   5
Series of prostaglandins




5/20/2012   Biochemistry for Medics   6
Characteristic features of
  prostaglandins




5/20/2012   Biochemistry for Medics   7
Functions of Prostaglandins




5/20/2012   Biochemistry for Medics   8
Prostacyclins and Thromboxanes-
  Chemistry and Functions




5/20/2012   Biochemistry for Medics   9
Functions of Prostcyclins




5/20/2012   Biochemistry for Medics   10
Functions of Thromboxanes




5/20/2012   Biochemistry for Medics   11
Synthesis of Prostaglandins




5/20/2012   Biochemistry for Medics   12
Steps of synthesis of Prostaglandins




5/20/2012   Biochemistry for Medics       13
Steps of synthesis of Prostanoids




5/20/2012   Biochemistry for Medics   14
Steps of synthesis of Prostanoids




5/20/2012   Biochemistry for Medics    15
PGH synthase Isoforms




5/20/2012   Biochemistry for Medics   16
Significance of PGH synthase isoforms




5/20/2012   Biochemistry for Medics      17
Inhibitors of Prostanoid synthesis




5/20/2012   Biochemistry for Medics    18
Selective V/S Non Selective COX
   inhibition




5/20/2012   Biochemistry for Medics   19
Catabolism of Prostaglandins




5/20/2012   Biochemistry for Medics   20
Leukotrienes




5/20/2012   Biochemistry for Medics   21
Lipoxins




5/20/2012   Biochemistry for Medics   22
Steps of synthesis of Leukotrienes




5/20/2012   Biochemistry for Medics    23
Steps of synthesis of Leukotrienes




5/20/2012   Biochemistry for Medics    24
Functions of Leukotrienes




5/20/2012   Biochemistry for Medics   25
Steps of synthesis of Lipoxins




5/20/2012   Biochemistry for Medics   26
Steps of Synthesis of Lipoxins




5/20/2012   Biochemistry for Medics   27
Slow-reacting substance of anaphylaxis
 (SRS-A)




5/20/2012   Biochemistry for Medics       28
Reason for Aspirin induced Asthma




5/20/2012   Biochemistry for Medics   29
Reason for Aspirin induced Asthma




5/20/2012   Biochemistry for Medics    30
Pharmacological applications of
 Eicosanoids




5/20/2012   Biochemistry for Medics   31
Pharmacological applications of
 Eicosanoids(Contd.)




5/20/2012   Biochemistry for Medics   32
Pharmacological applications of
Eicosanoids(Contd.)




5/20/2012   Biochemistry for Medics   33

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