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1. NIOSOMES, AN EXCELLENT TOOL FOR NOVEL DRUG DELIVERY SYSTEM
Authors- ALAM M, GOYAL G
Department of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab
 Design and Development of Novel Drug Delivery
System (NDDS) has two properties – first it should
deliver the drug in accordance with a predefined rate,
and second it should release therapeutically effective
amount of drug at the site of action.
 The main aim of development of noisome is to control
the release of drug in a sustained way modification of
distribution profile of drug, and the targeting of the
drug to the specific body site.
Introduction
Poster ID:D-D06
Branch: M.PHARM
Oral route
delivery
Transdermal
delivery
Hormone delivery
Diagnostic
markers
Approaches of Niosomes
Hand shaking
method
(lipid film
hydration)
Micro
fluidization
Ether
injection
Formation of
noisome from
proniosome
Multiple
membrane
Reverse phase
evaporation
The Bubble
method
Ethanol
injection
Sonication
Methods of Preparation
ADVANTAGE
• Increase oral bioavailability.
• High patient compliance.
• Biodegradable & non immunogenic.
• Chemically stable.
• Osmotically active.
• Enhance skin penetration.
• High compatible with biological system.
• Low toxicity because of non-ionic nature.

2. Niosomes represent a promising drug delivery module.
They present a structure similar to liposome and hence
they can represent alternative vesicular systems with
respect to liposomes, due to the niosome ability to
encapsulate different types of drug within their multi
environmental structure. The usefulness of niosomes in
the in the delivery of proteins and biologicals can be
unsubstained with a wide scope in encapsulating toxic
drugs and anti-viral drugs. Noisome thought to be better
candidates of drug delivery due to various factors like cost,
stability, etc.
References
1. Nasir N, Noisome: An excellent tool for drug delivery, Published
by international journal of research in pharmacy & chemistry.
2. Singh S.K, Noisome: A control and novel drug delivery system,
published by BIOL Pharma.
Conclusion
Structure of Niosomes
Formation of
noisome
Cholesterol
Non-ionic
surfactant
TYPES OF NIOSOME
Small
unilamella
r vesicles
(SUV)
SIZE-25-
500nm
Large
unilamella
r vesicles
(LUV)
SIZE-0.1-
1µm
Multilame
llar
vesicles
(MLV)
SIZE-1-
5µm