De extinction


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  • 1 pound per dead thylacine
  • Jonathan Coddington
  • De extinction

    1. 1. De-extinction, should we? Undergraduate Seminar Jay Edneil Olivar “Gone” by Isabella Kirkland
    2. 2. Passenger Pigeon STATUS: Extinct
    3. 3. Golden Toad STATUS: Extinct
    4. 4. Cuban Begonia STATUS: Extinct Tree Snail STATUS: Extinct
    5. 5. Thylacine Thylacinus cynocephalus STATUS: Extinct
    6. 6. /thylacine/history/history.htm
    7. 7. Common thread? Humans FORCED them to EXTINCTION WWF global ESTIMATES that at LEAST 10,000 species go EXTINCT every year
    8. 8. Probable Reason for Extinction • Paul Martin, an American anthropologist, pointed out that MEGAFAUNAL EXTINCTIONS were due to the introduction of HUNTING and DOMESTICATION TECHNIQUES by our early ancestors • OVERKILL Hypothesis
    9. 9. De-extinction process by which humans GENETICALLY ENGINEER embryos of extant species to hopefully bring back extinct relatives
    10. 10. Revival Criteria
    11. 11.
    12. 12. De-extinction: History
    13. 13. Karyoplast from skin biopsy SB Revival Bucardo Spanish Ibex De-extinction: Bucardo
    14. 14. First ever revived species by Folch et al. 2003
    15. 15. SB Gastric-Brooding Frog Great Barred Frog De-extinction: Gastric-brooding Frog Embryos grown in medium
    16. 16. Results Bucardo Gastric-Brooding Frog Only one female Spanish Ibex got pregnant Life span of revived bucardo was 7 minutes; Died because of lung defects Embryo’s average life span is 10 days Genetically IDENTICAL to the extinct species
    17. 17. MAGE System Multiplex Automated Genome Engineering System
    18. 18. A B C
    19. 19. A. Genomes to Cells Assembly of the passenger pigeon genome Comparison of the assembled genome with the extant relative’s genome MAGE System
    20. 20. B. Cells to a Bird Creation of passenger pigeon stem cells Insertion of germ cells to rock pigeon eggs
    21. 21. C. A bird to a flock Breeding of Chimeras
    22. 22. Where are we now? • Part A (Genomes to Cell)
    23. 23. Are we playing God? “Did we play God when we drove these species to extinction?” “It was ENTIRELY human efforts that made them extinct.”
    24. 24. Are we playing God? “Humans have made a HUGE hole in nature…We could consider bringing them back to a world that MISSES them.” “What I think is important is that, if it's clear that we exterminated these species, then I think we not only have a MORAL OBLIGATION to see what we can do about it, but I think we've got a MORAL IMPERATIVE to try to do something, if we can.”
    25. 25. What are we going to do with the revived species?
    26. 26. Are the revived species really authentic?
    27. 27. De-extinction, should we?
    28. 28.