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1 of 14
Objectives
• Explain what is meant by the term
endocrine gland.
• Describe the cellular structure of an islet of
Langerhans from the pancreas.
• Outline the role of the pancreas as an
endocrine gland.
http://www-medlib.med.utah.edu/WebPath/ENDOHTML/ENDO032.html
`
Pancreas
• Exocrine Gland: a gland that secretes
externally through a duct
• Endocrine Gland: a gland that secretes
hormones into the bloodstream.
Pancreas
• The pancreas has an exocrine portion
that secretes digestive enzymes that
are carried through a duct to the
duodenum. The endocrine portion
consists of the pancreatic islets,
which secrete glucagons and insulin.
Objectives
• Explain how the blood glucose
concentration is regulated by negative
feedback control mechanisms, with
reference to insulin and glucagon.
• Discuss the importance of homeostasis in
mammals, and explain the principles of
homeostasis in terms of receptors,
effectors and negative feedback.
Hormones
• Most hormones circulate in blood, coming
into contact with essentially all cells.
However, a given hormone usually affects
only a limited number of cells, which are
called target cells. A target cell responds
to a hormone because it bears receptors
for the hormone.
• The effector is usually an organ.
Objectives
• Explain the advantages of treating
diabetics with human insulin produced by
genetic engineering.
Blood sugar

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Blood sugar

  • 1. Objectives • Explain what is meant by the term endocrine gland. • Describe the cellular structure of an islet of Langerhans from the pancreas. • Outline the role of the pancreas as an endocrine gland.
  • 2.
  • 4. Pancreas • Exocrine Gland: a gland that secretes externally through a duct • Endocrine Gland: a gland that secretes hormones into the bloodstream.
  • 5. Pancreas • The pancreas has an exocrine portion that secretes digestive enzymes that are carried through a duct to the duodenum. The endocrine portion consists of the pancreatic islets, which secrete glucagons and insulin.
  • 6. Objectives • Explain how the blood glucose concentration is regulated by negative feedback control mechanisms, with reference to insulin and glucagon. • Discuss the importance of homeostasis in mammals, and explain the principles of homeostasis in terms of receptors, effectors and negative feedback.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12. Hormones • Most hormones circulate in blood, coming into contact with essentially all cells. However, a given hormone usually affects only a limited number of cells, which are called target cells. A target cell responds to a hormone because it bears receptors for the hormone. • The effector is usually an organ.
  • 13. Objectives • Explain the advantages of treating diabetics with human insulin produced by genetic engineering.