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Common Medication
Ordering Errors
Niloofar Alikashani RPH, BCPS
Medication Safety Pharmacist
© 2017 Virginia Mason Medical Center
Objectives
Learn about common medication
ordering errors that can be dangerous
to the patient
2
© 2017 Virginia Mason Medical Center
Medication Administration Times
3
© 2017 Virginia Mason Medical Center
Default Start times
4
EXCEPTIONS:
Frequency Defaults to next
administration time
if within
Daily 12 hours
Every morning 12 hours
Every evening 12 hours
Q12 HR 6 hours
Q8 HR 4 hours
© 2017 Virginia Mason Medical Center
Default Start Times
5
© 2017 Virginia Mason Medical Center
Review Requested Start
Date/Time
6
© 2017 Virginia Mason Medical Center
Review Next administration time to
avoid doses being given too close
7
When entering order details, the Requested Start Date/
Time, is by default closed
Clicking within the entry field or clicking the review schedule
link at the top of the details section will expand the
Requested Start Date/ Time to view subsequent
administration times
© 2017 Virginia Mason Medical Center
Medication Priority
8
© 2017 Virginia Mason Medical Center
Medication Priority
• When an order is placed as a STAT or NOW order, a dose
will be timed to be given NOW and the subsequent dose will
be given when the next scheduled administration is due.
This could cause a situation where the patient is over
medicated.
• It is vital that when placing a STAT or NOW order that the
Requested Start Date/Time field is expanded and
addressed.
9
© 2017 Virginia Mason Medical Center
Medication Priority
10
© 2017 Virginia Mason Medical Center
Skip Administration
You will also see a red exclamation mark icon also highlighting
that next dose is too close
The next administration will likely need to be skipped. This
can be indicated in the Request Start Date/ Time window by
checking the box for Skip Administration
11
© 2017 Virginia Mason Medical Center
Medication Priority
12
© 2017 Virginia Mason Medical Center
Medication Administration Times
13
Can change standard administration
times by:
© 2017 Virginia Mason Medical Center
Medication Administration Times
14
© 2017 Virginia Mason Medical Center
Scenarios
What is the default start time?
1. 0800H order Lisinopril 10mg po daily?
0900H
2. 0800H order Lisinopril 10mg po daily NOW
0800H & 0900H
3. 1300H order metoprol 25mg po q12HR?
1300H
4. 2000H order metoprol 25mg po q12HR?
2100H
5. 1900H order insulin glargine 10 units subq bid
before bkfst and dinner
0730H next am
15
© 2017 Virginia Mason Medical Center
Changes in Dose
If a change to a dose is made after the scheduled time, the dose
modification will ONLY be made for doses scheduled in the future.
That past due dose will NOT be modified. If this modification is
meant for that past due dose, you MUST alert the RN
Important to look at MAR to see when the dose was scheduled
16
© 2017 Virginia Mason Medical Center
Changes in Dose
17
Old doseNew dose
© 2017 Virginia Mason Medical Center
Continuous Infusion-Stop orders
• When placing an order for
continuous medications (for example
heparin, eptifibatide, insulin…), the
RN will NOT get an alert/task for the
Stop Date/Time.
• The provider must call RN and
communicate when the continuous
drip should be stopped.
18
© 2017 Virginia Mason Medical Center
How are “Additional Instructions”
seen by MD vs RPH vs RN
MD
19
© 2017 Virginia Mason Medical Center
How are “Additional Instructions”
seen by MD vs RPH vs RN
20
RPH
© 2017 Virginia Mason Medical Center
How are “Additional Instructions”
seen by MD vs RPH vs RN
21
© 2017 Virginia Mason Medical Center
How are “Additional Instructions”
seen by MD vs RPH vs RN
RN
22
© 2017 Virginia Mason Medical Center
How are Order Comments seen by
MD vs RPH vs RN
23
MD
© 2017 Virginia Mason Medical Center
How are Order Comments seen by
MD vs RPH vs RN
24
RPH
© 2017 Virginia Mason Medical Center
How are Order Comments seen by
MD vs RPH vs RN
RN
25
© 2017 Virginia Mason Medical Center
Banner Weight
26
© 2017 Virginia Mason Medical Center
Who can order chemo?
Initiated by an authorized prescriber
• Attendings
• Physician’s assistants, ARNPs, and
pharmacists with appropriate
privileging
NOT MEDICAL INTERNS OR
RESIDENTS
27
© 2017 Virginia Mason Medical Center
Transitioning patients on Direct Oral
Anticoagulants to Heparin Infusion
• At VMMC, we monitor heparin infusion
using anti-Xa (goal: 0.3-0.7)
• Patients who are on Xa inhibitor DOACs
(apixaban, rivaroxaban & edoxaban) and
transitioned to heparin infusion end up
having high anti-Xa levels resulting in the
RN stopping the drip & calling provider for
next step
• Patients on either apixaban, rivaroxaban
or edoxaban need to be transitioned to
PTT monitored heparin to avoid lab
interference 28
© 2017 Virginia Mason Medical Center
Heparin Weight Based Order Set
29
© 2017 Virginia Mason Medical Center
Transitioning patients on Direct Oral
Anticoagulants to Heparin Infusion
• Pharmacist orders baseline PTT
• Based on renal function, timing of last
dose & indication, determines when to
start heparin gtt and when to transition
back to anti-Xa monitoring heparin
protocol
• Expect to see a pharmacy progress note
on start of heparin gtt and transition to
anti-Xa monitoring heparin infusion
• Rate adjusted by RN using the infusion
adjustment chart
30
© 2017 Virginia Mason Medical Center
Why transitioning back to anti-Xa
monitoring ASAP?
• Anti-Xa is more accurate
• No validated heparin reagent curve so goal PTT is an estimate of
therapeutic values
• PTT can be prolonged by
 Lupus anticoagulant positive
 Liver disease
 DIC
 Factor deficiencies
 Von Willebrand disease
 Circulating factor inhibitors
• PTT response to UFH may be reduced by
 inflammation
 elevated factor VIII levels due to malignancy, acute
thrombosis and major surgery
• PTT may be shortened by Antithrombin deficiency
31
© 2017 Virginia Mason Medical Center
Pharmacy to Dose Vancomycin
Choose the appropriate goal and renal function
32
© 2017 Virginia Mason Medical Center
Summary
• When placing orders, review start time and next
administration time
• Can skip administration times & determine
associated administration time with each
frequency
• Additional Instructions->RN
• Order Comments->Pharmacist
• When transitioning patients from factor Xa
inhibitor DOACs to heparin infusion, consult
pharmacy
• When having to dose meds based on weight,
double check weight history. Do not rely on
banner weight
33
© 2017 Virginia Mason Medical Center
Questions
34
Medication Ordering Errors

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Medication Ordering Errors

  • 1. Common Medication Ordering Errors Niloofar Alikashani RPH, BCPS Medication Safety Pharmacist
  • 2. © 2017 Virginia Mason Medical Center Objectives Learn about common medication ordering errors that can be dangerous to the patient 2
  • 3. © 2017 Virginia Mason Medical Center Medication Administration Times 3
  • 4. © 2017 Virginia Mason Medical Center Default Start times 4 EXCEPTIONS: Frequency Defaults to next administration time if within Daily 12 hours Every morning 12 hours Every evening 12 hours Q12 HR 6 hours Q8 HR 4 hours
  • 5. © 2017 Virginia Mason Medical Center Default Start Times 5
  • 6. © 2017 Virginia Mason Medical Center Review Requested Start Date/Time 6
  • 7. © 2017 Virginia Mason Medical Center Review Next administration time to avoid doses being given too close 7 When entering order details, the Requested Start Date/ Time, is by default closed Clicking within the entry field or clicking the review schedule link at the top of the details section will expand the Requested Start Date/ Time to view subsequent administration times
  • 8. © 2017 Virginia Mason Medical Center Medication Priority 8
  • 9. © 2017 Virginia Mason Medical Center Medication Priority • When an order is placed as a STAT or NOW order, a dose will be timed to be given NOW and the subsequent dose will be given when the next scheduled administration is due. This could cause a situation where the patient is over medicated. • It is vital that when placing a STAT or NOW order that the Requested Start Date/Time field is expanded and addressed. 9
  • 10. © 2017 Virginia Mason Medical Center Medication Priority 10
  • 11. © 2017 Virginia Mason Medical Center Skip Administration You will also see a red exclamation mark icon also highlighting that next dose is too close The next administration will likely need to be skipped. This can be indicated in the Request Start Date/ Time window by checking the box for Skip Administration 11
  • 12. © 2017 Virginia Mason Medical Center Medication Priority 12
  • 13. © 2017 Virginia Mason Medical Center Medication Administration Times 13 Can change standard administration times by:
  • 14. © 2017 Virginia Mason Medical Center Medication Administration Times 14
  • 15. © 2017 Virginia Mason Medical Center Scenarios What is the default start time? 1. 0800H order Lisinopril 10mg po daily? 0900H 2. 0800H order Lisinopril 10mg po daily NOW 0800H & 0900H 3. 1300H order metoprol 25mg po q12HR? 1300H 4. 2000H order metoprol 25mg po q12HR? 2100H 5. 1900H order insulin glargine 10 units subq bid before bkfst and dinner 0730H next am 15
  • 16. © 2017 Virginia Mason Medical Center Changes in Dose If a change to a dose is made after the scheduled time, the dose modification will ONLY be made for doses scheduled in the future. That past due dose will NOT be modified. If this modification is meant for that past due dose, you MUST alert the RN Important to look at MAR to see when the dose was scheduled 16
  • 17. © 2017 Virginia Mason Medical Center Changes in Dose 17 Old doseNew dose
  • 18. © 2017 Virginia Mason Medical Center Continuous Infusion-Stop orders • When placing an order for continuous medications (for example heparin, eptifibatide, insulin…), the RN will NOT get an alert/task for the Stop Date/Time. • The provider must call RN and communicate when the continuous drip should be stopped. 18
  • 19. © 2017 Virginia Mason Medical Center How are “Additional Instructions” seen by MD vs RPH vs RN MD 19
  • 20. © 2017 Virginia Mason Medical Center How are “Additional Instructions” seen by MD vs RPH vs RN 20 RPH
  • 21. © 2017 Virginia Mason Medical Center How are “Additional Instructions” seen by MD vs RPH vs RN 21
  • 22. © 2017 Virginia Mason Medical Center How are “Additional Instructions” seen by MD vs RPH vs RN RN 22
  • 23. © 2017 Virginia Mason Medical Center How are Order Comments seen by MD vs RPH vs RN 23 MD
  • 24. © 2017 Virginia Mason Medical Center How are Order Comments seen by MD vs RPH vs RN 24 RPH
  • 25. © 2017 Virginia Mason Medical Center How are Order Comments seen by MD vs RPH vs RN RN 25
  • 26. © 2017 Virginia Mason Medical Center Banner Weight 26
  • 27. © 2017 Virginia Mason Medical Center Who can order chemo? Initiated by an authorized prescriber • Attendings • Physician’s assistants, ARNPs, and pharmacists with appropriate privileging NOT MEDICAL INTERNS OR RESIDENTS 27
  • 28. © 2017 Virginia Mason Medical Center Transitioning patients on Direct Oral Anticoagulants to Heparin Infusion • At VMMC, we monitor heparin infusion using anti-Xa (goal: 0.3-0.7) • Patients who are on Xa inhibitor DOACs (apixaban, rivaroxaban & edoxaban) and transitioned to heparin infusion end up having high anti-Xa levels resulting in the RN stopping the drip & calling provider for next step • Patients on either apixaban, rivaroxaban or edoxaban need to be transitioned to PTT monitored heparin to avoid lab interference 28
  • 29. © 2017 Virginia Mason Medical Center Heparin Weight Based Order Set 29
  • 30. © 2017 Virginia Mason Medical Center Transitioning patients on Direct Oral Anticoagulants to Heparin Infusion • Pharmacist orders baseline PTT • Based on renal function, timing of last dose & indication, determines when to start heparin gtt and when to transition back to anti-Xa monitoring heparin protocol • Expect to see a pharmacy progress note on start of heparin gtt and transition to anti-Xa monitoring heparin infusion • Rate adjusted by RN using the infusion adjustment chart 30
  • 31. © 2017 Virginia Mason Medical Center Why transitioning back to anti-Xa monitoring ASAP? • Anti-Xa is more accurate • No validated heparin reagent curve so goal PTT is an estimate of therapeutic values • PTT can be prolonged by  Lupus anticoagulant positive  Liver disease  DIC  Factor deficiencies  Von Willebrand disease  Circulating factor inhibitors • PTT response to UFH may be reduced by  inflammation  elevated factor VIII levels due to malignancy, acute thrombosis and major surgery • PTT may be shortened by Antithrombin deficiency 31
  • 32. © 2017 Virginia Mason Medical Center Pharmacy to Dose Vancomycin Choose the appropriate goal and renal function 32
  • 33. © 2017 Virginia Mason Medical Center Summary • When placing orders, review start time and next administration time • Can skip administration times & determine associated administration time with each frequency • Additional Instructions->RN • Order Comments->Pharmacist • When transitioning patients from factor Xa inhibitor DOACs to heparin infusion, consult pharmacy • When having to dose meds based on weight, double check weight history. Do not rely on banner weight 33
  • 34. © 2017 Virginia Mason Medical Center Questions 34