2. • What Is HIV?
HIV (human immunodeficiency virus) is a virus that attacks
cells that help the body fight infection, making a person more
vulnerable to other infections and diseases.
4. Stages of HIV Infection:
■ Stages of Infection – (assuming no treatment) ...
■ Stage 1: Infection. ...
■ Stage 2: Asymptomatic. ...
■ Stage 3: Symptomatic. ...Over time the immune system
becomes damaged and weakened by HIV and symptoms
develop. Initially they can be mild but they do worsen,
symptoms include fatigue, weight loss, mouth ulcers, thrush
and severe diarrhea
■ 4: AIDS/Progression of HIV to AIDS.
8. Subjective Data:
■ Cough: Insidious onset
■ productive-yellow colored sputum.
■ Blood stained
■ more in recumbent posture
■ Fever : intermittent high grade no chills or rigors
■ Oral lesions- white in color not associated with pain with gradually
increasing in nature.
9. Objective Data:
■ Hb:8.1g%
■ TC : 240ocells cells / cum D
■ C : N68 L28 E3
■ PLATELETS : 3-3 lakhs
■ Mantoux: Negative
■ HIV ( Elisa ):Positive
■ Thro for fungus : negative
■ Sputum for AFB : negative
■ CXR : B / L basal bronchiectasis
CT thorax : B / L bronchiectasis and features of infective bronchiolitis .
B / L hilar and mediastinal lymphadenopathy
11. Past History:
■ Scaly skin lesions over both legs :3 years
■ Recurrent respiratory infections:1 12 years
■ Similar oral lesions: 1Year
■ Loose mucoid stools , on & off : 1 year
■ P/H/ O febrile seizures was on regular AED'S till 3
years of age .
12. Goals of Treatment:
■ People living with HIV should be active participant in their
health management and requires an understanding of the
HIV infection, management and treatment.
■ Attention to growth , nutrition and immunization of child .
■ Treatment and prevention of opportunistic infections
Antiretroviral therapy .
13. Tab. Cotrimoxazole (sulfamethoxazole and trimethoprim):
• INDICATION: treatment for pneumocystis jirovecii pneumonia
• ADR: Nausea, vomiting, anorexia, seizures.
• CONTRAINDICATION: hypersensitivity
• INTERACTION: ACE inhibitors ,amiodarone, anti-diabetic drugs.
• DOSE: 15TMP/kg/day in 2 divided doses for 3 times.
14. Tab. ISONIAZID (10-15mg)
• INDICATION : treatment for TB (highly recommended for all children living
with HIV)
• ADVERSE DRUG REACTION: increased serum transaminase level, anorexia,
dizziness and Hepatotoxicity.
• CONTRAINDICATION: acute liver disease, fatal hepatitis.
• INTERACTION: Antacids, corticosteroids.
15. Tab. Zidovudine (300mg)
• INDICATION : treatment for HIV.
• ADVERSE DRUG REACTION: anorexia, weakness, fever, headache,
nausea, vomiting.
• CONTRAINDICATIONS: fatty liver disease, bone marrow
suppression.
• INTERACTIONS: Probenecid, fluconazole and ganciclovir.