Beclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 plays an important role in tumorigenesis, and neurodegeneration, being implicated in the autophagic programmed cell death. Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors. Anti-Beclin-1 - http://www.stjohnslabs.com/beclin-1-antibody-2?filter_name=stj97761 Join our Antibody Validation Project - http://www.stjohnslabs.com/services/antibody-validation