This document summarizes a project to estimate the effects of salinity intrusion due to climate change and sea level rise on the Georgia and South Carolina coasts. The project integrated three models - a global circulation model, a watershed model, and artificial neural network estuary models embedded in decision support systems. The models were calibrated using historical data from two example estuaries - the Pee Dee River basin and Lower Savannah River. The calibrated models were used to predict salinity levels and intrusion events under different climate and sea level rise scenarios to assess vulnerability for coastal utilities. The method developed can help utilities evaluate risks from climate change using existing long-term, site-specific data and modeling tools.