Suzanne Ginsburg discusses strategies for addressing the fragmentation in smartphone app development, distinguishing between web and native apps. She outlines considerations for designers, such as the need for device access, multitasking, and monetization strategies, and presents three approaches: the 'one trick pony', 'o.k. corral', and 'trojan horse'. The talk emphasizes the importance of understanding user needs and platform differences while considering both native and web app options.