The WHO FCTC provides solutions to the global tobacco epidemic through six key measures: monitor tobacco use, protect from smoke, offer help to quit, warn about dangers, ban advertising and promotions, and raise taxes. Implementation has led to rapid decreases in smoke exposure and heart attacks. Most countries have implemented some measures, though few have comprehensively adopted all six. Recent developments include new legislation in several countries. The success of the WHO FCTC depends on empowering comprehensive implementation of all effective measures.