ELEMENTARY PARTICLES OF MATTER
Matter is made up of discrete particles, the main ones are:-
1. Atoms 2. Ions 3. Molecules - (AIM)
DEFINITION OF ATOMS
An atom is the smallest particle of an element which can take part in a chemical reaction
THE CONSTITUENTS OF ATOMS
Rutherford in 1911 threw more light on the nature of the atom. He demonstrated that atom is made up of sub-particles which are called:
1. Proton 2. Neutron 3. Electron.
He discovered that the protons and neutrons are concentrated in the nucleus of an atom, while the electrons are revolving round the nucleus.
J.J THOMPSON’S MODEL
J.J Thompson described the atom as being made up of a mixture of positive (Protons) and negative (Electrons) charges.
LORD RUTHERFORD’S MODEL
Lord Rutherford described the atom as being made up of Positive (Protons) and Neutral (Neutrons) charges in its centre (nucleus) while the negative charges (electrons) rotates around its orbit.
He used the planetary bodies rotating around the sun to describe the structure of atoms.
CHARACTERISTICS OF PROTON, ELECTRON AND NEUTRON
DALTON’S ATOMIC THEORY
In 1808, John Dalton proposed the Atomic Theory which can be summarised as follows:
All elements are made up of small, indivisible particles called atoms.
Atoms can neither be created nor destroyed.
Atoms of the same elements are alike in every aspect, and differ from atoms of all other elements.
When atoms combine with other atoms, they do so in simple ratios.
All chemical changes result from the combination or the separation of atoms.
The Atomic Theory was partially supported by experimental evidences deduced from the Law of Conservation of Mass, the Law of Definite Proportions, the Law of Multiple Proportions and so on. It could not explain electrolysis and certain other phenomena. As a result of new discoveries, Dalton’s original Atomic Theory has undergone several modifications but the principal aspects as outlined above are still useful in the study of chemistry.
MODIFICATIONS OF DALTON’S ATOMIC THEORY
All Elements Are Made Up Of Small Indivisible Particles Called Atoms: This statement has been proven wrong by Rutherford’s discovery – the atom is built up of three main types of sub-particles: the proton, the electron, the neutron. It is not an indivisible solid piece.
The Atom Can Neither Be Created Nor Destroyed: This statement still holds good for ordinary chemical reactions and is embodied in the basic Law of Conservation of Mass. During a nuclear reaction, such as the fission of Uranium – 235, the nucleus is broken up into smaller units which form simpler atoms while a tremendous amount of heat energy is released. These changes that occur during nuclear fission destroy the atoms of the element involved.
The Atoms Of The Same Elements Are Alike In Every Aspect And Differ From Atoms Of All Other Elements: The discovery of isotopes makes this statement unacceptable. Chlorine, for example has two different atom
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
ELEMENTARY PARTICLES OF MATTER
Matter is made up of discrete particles, the main ones are:-
1. Atoms 2. Ions 3. Molecules - (AIM)
DEFINITION OF ATOMS
An atom is the smallest particle of an element which can take part in a chemical reaction
THE CONSTITUENTS OF ATOMS
Rutherford in 1911 threw more light on the nature of the atom. He demonstrated that atom is made up of sub-particles which are called:
1. Proton 2. Neutron 3. Electron.
He discovered that the protons and neutrons are concentrated in the nucleus of an atom, while the electrons are revolving round the nucleus.
J.J THOMPSON’S MODEL
J.J Thompson described the atom as being made up of a mixture of positive (Protons) and negative (Electrons) charges.
LORD RUTHERFORD’S MODEL
Lord Rutherford described the atom as being made up of Positive (Protons) and Neutral (Neutrons) charges in its centre (nucleus) while the negative charges (electrons) rotates around its orbit.
He used the planetary bodies rotating around the sun to describe the structure of atoms.
CHARACTERISTICS OF PROTON, ELECTRON AND NEUTRON
DALTON’S ATOMIC THEORY
In 1808, John Dalton proposed the Atomic Theory which can be summarised as follows:
All elements are made up of small, indivisible particles called atoms.
Atoms can neither be created nor destroyed.
Atoms of the same elements are alike in every aspect, and differ from atoms of all other elements.
When atoms combine with other atoms, they do so in simple ratios.
All chemical changes result from the combination or the separation of atoms.
The Atomic Theory was partially supported by experimental evidences deduced from the Law of Conservation of Mass, the Law of Definite Proportions, the Law of Multiple Proportions and so on. It could not explain electrolysis and certain other phenomena. As a result of new discoveries, Dalton’s original Atomic Theory has undergone several modifications but the principal aspects as outlined above are still useful in the study of chemistry.
MODIFICATIONS OF DALTON’S ATOMIC THEORY
All Elements Are Made Up Of Small Indivisible Particles Called Atoms: This statement has been proven wrong by Rutherford’s discovery – the atom is built up of three main types of sub-particles: the proton, the electron, the neutron. It is not an indivisible solid piece.
The Atom Can Neither Be Created Nor Destroyed: This statement still holds good for ordinary chemical reactions and is embodied in the basic Law of Conservation of Mass. During a nuclear reaction, such as the fission of Uranium – 235, the nucleus is broken up into smaller units which form simpler atoms while a tremendous amount of heat energy is released. These changes that occur during nuclear fission destroy the atoms of the element involved.
The Atoms Of The Same Elements Are Alike In Every Aspect And Differ From Atoms Of All Other Elements: The discovery of isotopes makes this statement unacceptable. Chlorine, for example has two different atom
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
4. Explanation:
Option B is not true as in a molecule of ammonia, there are
1 nitrogen atom and 3 hydrogen atoms.
5. Explanation:
Option A is not true as different compounds have different
mass numbers (different chemical formulae).
Option B is not true as HClO3 does not contain carbon atoms.
Option D is not true as the compounds have different
chemical formulae (different number of electrons).
6. Explanation:
If the diagram shows 1 type of atom, it is an element.
If the diagram shows 2 or more type of atoms chemically
bonded, it is a compound.
Mixture Element
Mixture
Compound
7. Map It Out
Start from here.
The only sub-atomic particle
that has no charge is the
neutron.
8. ChallengeYourself
H2O / CO2 / CO / HCl /
NH3 / NO2 / NO / SO2
H2O / CO2 / NO2 / SO2
Accept any other suitable answers
[1]
[1]
10. Lithium has an atomic number of 3 (number of protons) and
mass number of 7 (3 protons + 4 neutrons). [1]
11. In an atom, the number of protons (positively
charged) is equal to the number of electrons
(negatively charged). [1]
Hence, the positive charge of the protons is balanced
by the negative charge of the electrons. [1]
12. No, atoms do not have a unique number of neutrons. [1]
13. Yes, each atom has a unique number of protons. [1]
Atoms are arranged in ascending order of atomic
number (number of protons) in the PeriodicTable.
14. An atom of gold (Au) has 79 protons, 79 electrons and
118 neutrons. [2]
15. •
Use PeriodicTable and search for
atomic number 53 and 80 number of protons = number of electrons
number of neutrons = mass number atomic number
Atomic number is the number of protons
[1]