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BRUNO OTILIO
Ciência sem Fronteiras
Internship at Mayo Clinic
INTRODUCTION
Places that I lived on
Bloomington, IN
Brookings, SD
Rochester, MN
A brief definition on Ultrasound
What is that?
Internship
Mayo Clinic
Elastography
My fronts
BLOOMINGTON, IN
3
4
5
There were squirrels on everywhere!!
6
BROOKINGS, SD
7
8
9
10
11
12
13
ROCHESTER, MN
14
15
“THE FUN TIME FINISHED AND THE WORK
TIME HAS BEGUN”
Stewie Griffin - Family Guy
16
ULTRA-WHAT?
What is a sound?
17
SOUND
[1] - http://healthstoriesforkids.com/the-journey-of-ear-infections/
[2] - http://hyperphysics.phy-astr.gsu.edu/hbase/sound/tralon.html
[1]
[2]
Mechanical Electric
18
What frequency can humans hear? -> 20Hz - 20kHz
[3] - http://healingsounds.co.za/content/about-sound-1
[3]
Ultrasound = f>20kHz
19
IF HUMANS CANNOT HEAR IT… WHY IS THAT IMPORTANT?
[4] - http://www.raymarine.com/view/?id=3173
History:
– First practical application, 1912 unsuccessful search
for Titanic 

– WWII brought massive military research-SONAR
(SOund Navigation And Ranging) -> SONAR

– Mid-century used for non-destructive testing of
materials 

– First used as diagnostic tool in 1942 for localizing
brain tumors 

– 1950’s 2D gray scale images 

– 1965 real-time imaging 



20
SONOGRAPHY ULTRASOUND IMAGING
➤It uses high-frequency sound waves to view inside
the body.

➤They can also show movement of the body's
internal organs as well as blood flowing through
the blood vessels.

➤Unlike X-ray imaging, there is no ionizing
radiation exposure associated with ultrasound
imaging.

➤A transducer is placed directly on the skin or inside
a body opening. 

➤ Gel is applied to the skin so that the ultrasound
waves are transmitted from the transducer through
the gel into the body.

➤The ultrasound image is produced based on the
reflection of the waves off of the body structures.

➤The strength (amplitude) of the sound signal and
the time it takes for the wave to travel through the
body provide the information necessary to produce
an image.http://www.medicalnewstoday.com/articles/245491.php?page=2
http://www.fda.gov/Radiation-EmittingProducts/RadiationEmittingProductsandProcedures/MedicalImaging/ucm115357.htm
21
HOW IS ULTRASOUND CREATED?
GE LogiQ 7 Transducers
http://www.vaultrasound.com/educational-resources/ultrasound-physics/transducers/
Verasonics
In medicine, ultrasound (f > 1 MHz) is used to detect changes in
appearance, size or contour of organs, tissues, and vessels or detect
abnormal masses, such as tumors.
Radiologyinfo.org
(typically 20–600 V at 1 kHz).
22
TRANSDUCERS AND IMAGING
➤ Transducer element: > 256
elements measuring 1mm X 10
mm each.
➤ Real-Time US -> 16 frames/sec
must be displayed.
➤ Doppler Ultrasound: Doppler
ultrasound, a special application
of ultrasound, measures the
direction and speed of blood cells
as they move through vessels.
Acoustic waves’ velocity depends of the medium.
http://ultrasound-scanner.com/5-2-color-doppler-ultrasound-system.html
23
ULTRASOUND QUANTITIES AND UNITS
➤ Frequency: The range of 2 - 10
MHz.
➤ Propagation Speed: Typically, 1540
m/sec for soft tissue.
➤ Pulsed ultrasound: To achieve the
depth of resolution (milliseconds)
➤ US interaction with tissue:
Attenuation
➤ Angle of Incidence (Snell’s law)
24
Gel is important for that!!
Transducer
High frequency Low frequency
better resolution weak resolution
attenuation attenuation
REFERENCES
➤ John E. Aldrich, PhD. Basic physics of ultrasound imaging
➤ Jens E. Wilhjelm, Andreas Illum, Martin Kristensson and Ole Trier Andersen. Medical diagnostic
ultrasound - physical principles and imaging. Biomedical Engineering, DTU Elektro Technical
University of Denmark
➤ P N T Wells. Ultrasonic imaging of the human body. Department of Medical Physics and
Bioengineering and Centre for Physics and Engineering Research in Medicine, Bristol General
Hospital, Bristol BS1 6SY, UK.
25

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WIEB

  • 1. BRUNO OTILIO Ciência sem Fronteiras Internship at Mayo Clinic
  • 2. INTRODUCTION Places that I lived on Bloomington, IN Brookings, SD Rochester, MN A brief definition on Ultrasound What is that? Internship Mayo Clinic Elastography My fronts
  • 4. 4
  • 5. 5
  • 6. There were squirrels on everywhere!! 6
  • 8. 8
  • 9. 9
  • 10. 10
  • 11. 11
  • 12. 12
  • 13. 13
  • 15. 15
  • 16. “THE FUN TIME FINISHED AND THE WORK TIME HAS BEGUN” Stewie Griffin - Family Guy 16
  • 18. SOUND [1] - http://healthstoriesforkids.com/the-journey-of-ear-infections/ [2] - http://hyperphysics.phy-astr.gsu.edu/hbase/sound/tralon.html [1] [2] Mechanical Electric 18
  • 19. What frequency can humans hear? -> 20Hz - 20kHz [3] - http://healingsounds.co.za/content/about-sound-1 [3] Ultrasound = f>20kHz 19
  • 20. IF HUMANS CANNOT HEAR IT… WHY IS THAT IMPORTANT? [4] - http://www.raymarine.com/view/?id=3173 History: – First practical application, 1912 unsuccessful search for Titanic 
 – WWII brought massive military research-SONAR (SOund Navigation And Ranging) -> SONAR
 – Mid-century used for non-destructive testing of materials 
 – First used as diagnostic tool in 1942 for localizing brain tumors 
 – 1950’s 2D gray scale images 
 – 1965 real-time imaging 
 
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  • 21. SONOGRAPHY ULTRASOUND IMAGING ➤It uses high-frequency sound waves to view inside the body. ➤They can also show movement of the body's internal organs as well as blood flowing through the blood vessels. ➤Unlike X-ray imaging, there is no ionizing radiation exposure associated with ultrasound imaging. ➤A transducer is placed directly on the skin or inside a body opening. ➤ Gel is applied to the skin so that the ultrasound waves are transmitted from the transducer through the gel into the body. ➤The ultrasound image is produced based on the reflection of the waves off of the body structures. ➤The strength (amplitude) of the sound signal and the time it takes for the wave to travel through the body provide the information necessary to produce an image.http://www.medicalnewstoday.com/articles/245491.php?page=2 http://www.fda.gov/Radiation-EmittingProducts/RadiationEmittingProductsandProcedures/MedicalImaging/ucm115357.htm 21
  • 22. HOW IS ULTRASOUND CREATED? GE LogiQ 7 Transducers http://www.vaultrasound.com/educational-resources/ultrasound-physics/transducers/ Verasonics In medicine, ultrasound (f > 1 MHz) is used to detect changes in appearance, size or contour of organs, tissues, and vessels or detect abnormal masses, such as tumors. Radiologyinfo.org (typically 20–600 V at 1 kHz). 22
  • 23. TRANSDUCERS AND IMAGING ➤ Transducer element: > 256 elements measuring 1mm X 10 mm each. ➤ Real-Time US -> 16 frames/sec must be displayed. ➤ Doppler Ultrasound: Doppler ultrasound, a special application of ultrasound, measures the direction and speed of blood cells as they move through vessels. Acoustic waves’ velocity depends of the medium. http://ultrasound-scanner.com/5-2-color-doppler-ultrasound-system.html 23
  • 24. ULTRASOUND QUANTITIES AND UNITS ➤ Frequency: The range of 2 - 10 MHz. ➤ Propagation Speed: Typically, 1540 m/sec for soft tissue. ➤ Pulsed ultrasound: To achieve the depth of resolution (milliseconds) ➤ US interaction with tissue: Attenuation ➤ Angle of Incidence (Snell’s law) 24 Gel is important for that!! Transducer High frequency Low frequency better resolution weak resolution attenuation attenuation
  • 25. REFERENCES ➤ John E. Aldrich, PhD. Basic physics of ultrasound imaging ➤ Jens E. Wilhjelm, Andreas Illum, Martin Kristensson and Ole Trier Andersen. Medical diagnostic ultrasound - physical principles and imaging. Biomedical Engineering, DTU Elektro Technical University of Denmark ➤ P N T Wells. Ultrasonic imaging of the human body. Department of Medical Physics and Bioengineering and Centre for Physics and Engineering Research in Medicine, Bristol General Hospital, Bristol BS1 6SY, UK. 25