This article analyzes strategies for achieving optimal health in developing countries with high rates of HIV/AIDS. It uses an economic model to study how international goals of zero new HIV infections, zero deaths from AIDS, and zero discrimination in healthcare access can be achieved. The model finds that HIV vaccines may be effective before individuals reach the "seropositivity" threshold, and medical care may slow death rates after individuals pass the HIV threshold but before reaching the AIDS threshold. However, once the AIDS threshold is passed, existing tools are no longer effective at fighting the virus. Overall eradication requires public education to change behaviors and cooperation between governments, international organizations, and low-cost drug companies on prevention and treatment.