This document summarizes a presentation on how experience with cluster policies can inform the development of smart specialization strategies. It outlines three key differences between cluster policies and smart specialization strategies, but also notes important synergies. Specifically, it discusses how existing clusters can provide insights into analyzing regional contexts, ensuring stakeholder participation in governance, constructing a shared vision, identifying priorities, and integrating monitoring and evaluation. The presentation argues that rather than abandoning existing cluster policies, smart specialization strategies should build upon the experiences and assets developed through long-running cluster initiatives.