Sorghum and pearl millet are staple crops grown for subsistence in tropical countries. Less than 5% of annual production is commercially processed due to low productivity, high costs, and lack of processor awareness. Efforts to promote commercialization face challenges. Rural populations have low incomes and awareness. Marketing strategies must address awareness, acceptability, and availability of biofortified staple crops through opinion leaders, demonstrations, education, and ensuring hybrid varieties with higher nutrients are available at affordable prices through expanded distribution networks. The private sector aims to commercialize these crops but rural consumers are diverse with challenges around poverty, infrastructure, and health.