We are what we eat
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This document discusses the biochemistry of the molecules that make up living things. It focuses on carbohydrates, lipids, and proteins. Carbohydrates like glucose are a source of energy, while lipids store energy and make up cell membranes. Proteins have many roles including structure, transport, and catalyzing reactions as enzymes. The building blocks of proteins are amino acids, while the building blocks of carbohydrates and lipids are carbon-containing molecules. Overall, the document examines the essential macronutrients that power our bodies and allow for life.
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1. Lipids play major roles in cell structure and energy storage. Triacylglycerols are the main form of stored energy in mammals while phospholipids and cholesterol are components of cell membranes.
2. There are two main types of lipids - simple lipids like fats and oils which are esters of fatty acids and alcohols, and compound lipids which also contain phosphate, nitrogenous bases or other groups.
3. Triglycerides from the diet and from adipose tissue are broken down into fatty acids and glycerol. Fatty acids are transported to tissues via the bloodstream bound to albumin or within lipoproteins, then undergo beta-oxidation in the mitochondria to
Concepts in BiochemistryChapter 2Wendy Herndon, BIS, RDH, CD
Concepts in Biochemistry
Chapter 2
Wendy Herndon, BIS, RDH, CDA
Introduction
Dental professionals need to have a basic understanding of biochemistry
It is the foundation for understanding and applying the concepts of nutrition
What is Biochemistry?
It is the study of life at the molecular level
A molecule is:
The smallest particle of a substance that retains all the properties of the substance
A biomolecule is
Any molecule that is produced by a living cell or organism
https://www.youtube.com/watch?v=YO244P1e9QM
Metabolism involves
Production and use of energy which can come from dietary carbs, proteins, and lipids
Bioinformation involves
The transfer of biological information from DNA to RNA to protein which carries out all of the processes of life
DNA is deoxyribonucleic acid
RNA is Ribonucleic acid
3
Fundamentals
Atoms are:
Made of three tiny particles called:
Protons
Neutrons
Electrons
An atom itself is made up of three tiny kinds of particles called subatomic particles: protons, neutrons, and electrons. The protons and the neutrons make up the center of the atom called the nucleus and the electrons fly around above the nucleus in a small cloud. All matter is made up of atoms.
4
Fundamentals
Molecules are:
A group of atoms bonded together
An example is when two atoms of hydrogen bond with one atom of oxygen, it forms a water molecule
A molecule is a group of atoms bonded together
5
Fundamentals
The mass of the human body is made of atoms which form molecules (groups of atoms)
Molecules form cells (made up of billions of molecules)
Cells form tissues
Tissues form organs
Organs work together to form systems
Systems form organisms such as a human
Atomic Bonds
Ionic
Ionic bonds form between a positively charged metal and a negatively charged non-metal
An example of an ionic bond is the hydroxyapatite in enamel which is composed of ionic bonds between calcium and phosphate
Atomic Bonds
Covalent
-A covalent bond occurs when two non-metal atoms equally share electrons
-An example of this would be when nitrogen and oxygen bond together to form nitrous oxide
-Laughing gas
Carbon
Element
Carbon is the fourth most abundant element in the universe and is the building block of life on earth
Cells are made of many complex molecules called macromolecules
These include proteins, nucleic acids (RNA and DNA), carbohydrates, and lipids
The carbon atom has unique properties that allow it to form covalent bonds to as many as four different atoms, making this versatile element ideal to serve as the basic structural component, or “backbone,” of the macromolecules (many complex molecules)
Main Biomolecules in Nutrition
(any molecule formed by a living cell or organism)
The four major biomolecules are:
Carbohydrates
Lipids
Proteins
Nucleic acids
These biomolecules are characterized by the type of polymer or monomer they contain and by their function
A polymer is a large molecule containing repeating units kn ...
Lipids
Lipids are a group of organic compounds that include fats, oils, steroids, and phospholipids. They are insoluble in water and serve important functions in the body such as energy storage, insulation, and cell membrane structure. There are three main classes of lipids: triglycerides which include fats and oils, phospholipids including lecithin, and sterols such as cholesterol. Fats can be saturated, existing as solids at room temperature, or unsaturated and liquid. Hyperlipoproteinemia is a disorder where the body cannot break down lipids properly and is often genetic, leading to high lipid levels in the blood and symptoms like pancreatitis or lipid deposits. It is diagnosed via blood tests
Lipid metabolism
Fats (or triglycerides) within the body are ingested as food or synthesized by adipocytes or hepatocytes from carbohydrate
Fats
Fats, or lipids, are an important part of the human diet and body. They provide stored energy, aid in nutrient absorption, and have structural and regulatory roles. Lipids are composed of fatty acids and glycerol. They are classified and digested differently than carbohydrates or proteins. The body metabolizes lipids through various pathways to produce energy or build cell membranes and hormones.
Fats
Fats, or lipids, are an important part of the human diet and body. They provide stored energy, aid in nutrient absorption, and have structural and regulatory roles. Lipids are composed of fatty acids and glycerol. They are classified by their structure as saturated, monounsaturated, or polyunsaturated. Dietary lipids undergo digestion and absorption and are used for energy production or storage.
Lipid metabolism
Lipid metabolism involves the breakdown and synthesis of fats and involves several processes. Fats are obtained through food or synthesized in the body from carbohydrates. Hormones signal the need for energy storage or release from fat cells. Fatty acids and glycerol are released from triglycerides and transported to tissues where the liver uses some for energy and resynthesizes others to be stored or used by muscles. Lipid metabolism occurs through several pathways including beta-oxidation of fatty acids, fatty acid synthesis, and cholesterol transport.
lipidmetabolism-180815094346.pdf
Lipid metabolism involves the breakdown and synthesis of fats and involves several processes. Fats are obtained through food or synthesized in the body from carbohydrates. They are either oxidized to produce energy or used to synthesize new lipids. The liver plays a key role by breaking down fats and producing energy or converting them to ketones. Fatty acids are also stored in adipose tissue and mobilized when hormones signal the need for energy.
02 nutrition
The document discusses various topics related to nutrition including macromolecules that provide energy like proteins, carbohydrates, and fats. It describes the roles of the liver, vitamins, minerals, and enzymes in breaking down nutrients. Specific carbohydrates like monosaccharides, disaccharides, and polysaccharides are defined. The document also covers protein structure, fat types, cholesterol, blood sugar regulation, energy requirements, metabolic rate, and eating disorders like anorexia and bulimia.
Lipids.pptx
Lipids are organic compounds that serve important functions in the body. They include fats, oils, waxes, phospholipids, and steroids. Lipids serve as long-term energy stores, cushion and insulate organs, and form cellular membranes. Major types include triglycerides/fats and oils which are made of fatty acid chains, phospholipids which are amphipathic, and steroids including cholesterol. Saturated fats are generally solid while unsaturated fats are usually liquid. Lipids can be identified using an ethanol emulsion test.
Ch 14 Metabolism
The document discusses the digestive system and metabolism. It covers the major nutrients, including carbohydrates, lipids, proteins, vitamins, and minerals. It then discusses metabolism, including catabolism, anabolism, and how the body metabolizes carbohydrates, fats, and proteins. It also discusses the role of the liver in metabolism, including detoxification and producing cholesterol and proteins. Finally, it covers metabolic rate, body temperature regulation, and developmental aspects of the digestive system from fetal development through old age.
12. Nutrients and Metabolism
The document discusses nutrients and metabolism. It defines six categories of nutrients including carbohydrates, lipids, proteins, vitamins, and minerals. It describes the processes of catabolism, which breaks down molecules to produce energy, and anabolism, which uses energy to construct new molecules. Key metabolic pathways discussed include glycolysis, the Krebs cycle, and the electron transport system, which generate ATP through carbohydrate metabolism. Control of metabolic reactions is achieved through enzymes and cofactors.
Sec2topic1orgcompounds
A hotel in northern Germany is charging guests by their weight, with guests paying 50 euro cents per kilogram for their stay. The owner believes this will encourage guests to stay healthier and return more often. A 60kg guest would pay 30 euros, while a 100kg guest would pay 50 euros. The owner weighs guests at check-in, not check-out, so guests have no incentive to lose weight during their stay.
Classification of Lipids By Danish Shafi MIr.pptx
Lipids are a diverse group of compounds that include fats, oils, waxes, sterols like cholesterol, and phospholipids. They serve important structural and storage roles in cells and transport of fat-soluble vitamins and other compounds. Lipids are classified based on their structure as simple, compound, or derived lipids.
Carbohydrates, fats, and proteins
This document summarizes key nutrients that provide calories - carbohydrates, fats, and proteins. It describes the sources and functions of carbohydrates including sugars, starches, and fiber. It also discusses the different types of fats including saturated, unsaturated, and trans fats. Finally, it covers the sources and functions of protein as well as complete and incomplete protein sources and dietary recommendations.
Lipids
Lipids are classified based on their solubility properties. They are soluble in nonpolar solvents but insoluble in water. Lipids serve important functions like energy storage, forming cell membranes, and regulating cell activities. They can be classified as saponifiable or non-saponifiable based on whether they undergo alkaline hydrolysis. Fatty acids are the main constituents of lipids and contain a polar carboxyl group and a nonpolar hydrocarbon chain. Triacylglycerols are composed of fatty acids esterified to glycerol and can be solid fats or liquid oils. Polar lipids like glycerophospholipids and sphingolipids contain a polar head and nonpolar tails, making them essential components of
nutrition final.docx
The document defines key nutritional terms like nutrients, calories, carbohydrates, proteins, fats, vitamins, minerals, and fiber. It discusses micronutrients and macronutrients, classifying carbohydrates as simple or complex. It also outlines recommendations for daily intake of fibers, proteins, and vitamins/minerals. The document provides a case study on a 65-year-old male patient and recommends a healthy lifestyle to control his high cholesterol, blood pressure, blood sugar and weight, including reducing saturated fats, increasing fiber and physical activity, and weight loss.
Macromolecules Presentation.pptx
Macromolecules like carbohydrates, lipids, proteins, and nucleic acids are essential to human body functioning. Carbohydrates provide the main energy source, lipids provide stored energy reserves, proteins help form muscles and fight disease, and nucleic acids control our genetic structure. Enzymes play an important role in breaking down macromolecules into smaller units that the body can use. Carbohydrates break down into simple sugars, proteins into amino acids, lipids into fatty acids and glycerol, and nucleic acids store and carry genetic information in the form of DNA and RNA.
LIPID METABOLISM.pptx
Lipid metabolism involves the breakdown of fats into fatty acids to produce energy or the synthesis of new lipids from smaller molecules. Fats can be obtained from food or synthesized in the liver or adipose tissue. Lipids are stored as triglycerides in adipose tissue and mobilized for energy through lipolysis. The liver plays a key role in lipid metabolism by breaking down fats and producing energy, cholesterol, and phospholipids. Lipids are essential for many bodily functions when consumed in proper amounts.
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We are what we eat
- 1. We are what we eat: the biochemistry of life (or the biochemistry of the “operación bikini”)
- 3. Carbon-Based Molecules: The Basis for All Life Where do the carbon-containing molecules come from? Carbon atoms are central to all organisms because they’re found in carbohydrates, proteins, nucleic acids, and lipids — otherwise known as the structural materials of all living things Food
- 4. Providing energy: Carbohydrates The basic formula for carbohydrates is CH2O Carbohydrates are energy-packed compounds Source of near-immediate energy Hunger
- 5. Types of Carbohydrates Monosaccharides Polysaccharides Non digestible, dietary fiber Sugar, sweet and soluble glucose 4 calories/g
- 6. Supplying structure, energy, and more: Lipids High energy density (the ability to store lots of calories in a small space) Store energy Cushions and insulates the body and nerves.
- 7. Phospholipids: they’re part of the membranes of cells Steroids: generally used to create hormones Triglycerides: These fats and oils, which are made up of three fatty acid molecules and a glycerol molecule, are important for energy storage and insulation Types of lipids Cholesterol is a steroid molecule used to make testosterone and estrogen In people, fats form from an excess of glucose
- 8. A little bit more about triglycerides… Triglycerides composed of unsaturated fatty acids melt at lower temperatures than those with saturated fatty acids. most known for raising your LDL cholesterol (“bad” cholesterol) lower LDL cholesterol and raise HDL cholesterol ("good" cholesterol)
- 9. Making life possible: Proteins Amino acids are the building blocks of proteins All living organisms have only 20 different amino acids to form all the proteins Multiple functions: structural, transport, or signaling roles.
- 10. 20 Amino acids
- 11. Enzymes are proteins that speed up the rate of chemical reactions. Structural proteins reinforce cells and tissues. (i.e. colagen) Transport proteins move materials around cells and around the body. (i.e. hemoglobin) Types of proteins
- 12. Eating: the fire analogy 1 23
- 13. Eating: some famous diets Low carb diet High protein diet
- 14. Non fat milk Reduced fat milk 2% milkfat
- 16. Calories (100g)= 421 kcal Proteins: 27,5g Carbohydrates: 1,4g Fats: 34,0g Calories (100g)= 109,5 kcal Proteins: 18,6g Carbohydrates: 0,9g Fats: 3,5g Calories (100g)= 258 kcal Proteins: 12,0g Carbohydrates: 26,0g Fats: 11,8 g
- 17. Calories (100g)= 96 kcal Proteins: 1g Carbohydrates: 20,8g Fats: 0,2g Calories (100g)= 661 kcal Proteins: 12g Carbohydrates:10,5g Fats: 61,6g