The document provides instructions for a physical education lesson plan focusing on bending and flexing the knees. It includes warm-up exercises, activities to practice different motions like lunges and marches, and songs to sing while performing actions. The goal is to teach students about proper body mechanics and flexibility through physical movement and routines.
The document outlines several marketing predictions for 2015 based on research from sources like Forbes and thinkelite. It predicts that marketing will shift from globalization to personalization as consumers resist homogenization. There will also be a growing focus on internal communications as a key marketing asset. Additionally, visual storytelling will emerge as a main strategy for growing communities by establishing authenticity with audiences. Leveraging new technologies will help brands stay ahead of the curve.
This document discusses marketing managers and provides examples of good, bad, and ugly marketing managers. It discusses the qualities of a good marketing manager such as being a multi-tasker, customer centric, brand champion, understanding business well, and being a strategic thinker. It then provides examples of a good marketing manager from the "Ab Ki Baar Modi Sarkar" political campaign and a bad marketing manager from the failed launch of Nirma beauty soap. It also discusses an ugly marketing manager from the mistakes made during the overhaul of JC Penney's pricing scheme.
The document outlines several marketing predictions for 2015 based on research from sources like Forbes and thinkelite. It predicts that marketing will shift from globalization to personalization as consumers resist homogenization. There will also be a growing focus on internal communications as a key marketing asset. Additionally, visual storytelling will emerge as a main strategy for growing communities by establishing authenticity with audiences. Leveraging new technologies will help brands stay ahead of the curve.
The document discusses the growth of online retail in India. It notes that increasing internet and smartphone penetration along with rising incomes are driving more online shopping. Selling products exclusively online provides brands several advantages over traditional retail like higher visibility, direct customer access, and lower prices due to reduced costs. It also cites examples like Motorola seeing great success selling over 1 million phones through Flipkart within 5 months. The document concludes by addressing Mr. Karan Mehta, brand manager of Hiro Cycles, informing him that their new MX-1 mountain bike will launch in November 2014 selling only online, and requests a marketing plan be submitted.
The document provides instructions for a physical education lesson plan focusing on bending and flexing the knees. It includes warm-up exercises, activities to practice different motions like lunges and marches, and songs to sing while performing actions. The goal is to teach students about proper body mechanics and flexibility through physical movement and routines.
The document outlines several marketing predictions for 2015 based on research from sources like Forbes and thinkelite. It predicts that marketing will shift from globalization to personalization as consumers resist homogenization. There will also be a growing focus on internal communications as a key marketing asset. Additionally, visual storytelling will emerge as a main strategy for growing communities by establishing authenticity with audiences. Leveraging new technologies will help brands stay ahead of the curve.
This document discusses marketing managers and provides examples of good, bad, and ugly marketing managers. It discusses the qualities of a good marketing manager such as being a multi-tasker, customer centric, brand champion, understanding business well, and being a strategic thinker. It then provides examples of a good marketing manager from the "Ab Ki Baar Modi Sarkar" political campaign and a bad marketing manager from the failed launch of Nirma beauty soap. It also discusses an ugly marketing manager from the mistakes made during the overhaul of JC Penney's pricing scheme.
The document outlines several marketing predictions for 2015 based on research from sources like Forbes and thinkelite. It predicts that marketing will shift from globalization to personalization as consumers resist homogenization. There will also be a growing focus on internal communications as a key marketing asset. Additionally, visual storytelling will emerge as a main strategy for growing communities by establishing authenticity with audiences. Leveraging new technologies will help brands stay ahead of the curve.
The document discusses the growth of online retail in India. It notes that increasing internet and smartphone penetration along with rising incomes are driving more online shopping. Selling products exclusively online provides brands several advantages over traditional retail like higher visibility, direct customer access, and lower prices due to reduced costs. It also cites examples like Motorola seeing great success selling over 1 million phones through Flipkart within 5 months. The document concludes by addressing Mr. Karan Mehta, brand manager of Hiro Cycles, informing him that their new MX-1 mountain bike will launch in November 2014 selling only online, and requests a marketing plan be submitted.
Spark streaming provides stream processing functionality as an abstraction over core Spark. It processes data in micro-batches, where streaming data is buffered for a given interval and then processed as RDDs by core Spark. The processing time of each micro-batch must be less than the batch interval to avoid bottlenecks. Performance can be tuned by parallelizing data consumption from sources like Kafka, and balancing Spark partitions for parallel processing with available cores.
There are several types of shopping malls categorized based on their size, offerings, target customers, and location. Fashion/specialty centers are smaller high-end malls catering to wealthy customers within 5-15 miles. Community centers are larger than neighborhood centers, have discount department stores and apparel stores, and serve areas within 3-6 miles. Lifestyle centers combine retail with leisure amenities, have a cinema as a major tenant, and are located in affluent suburbs.
This document discusses distributed system models and enabling technologies for scalable computing over the Internet. It covers the evolution of computing from centralized to distributed models utilizing multiple computers over the Internet. Key topics include high-performance computing, high-throughput computing, different levels of parallelism, innovative applications, and new paradigms like the Internet of Things. Computer clusters, virtualization, and their design are also summarized.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Congestive Heart failure is caused by low cardiac output and high sympathetic discharge. Diuretics reduce preload, ACE inhibitors lower afterload, beta blockers reduce sympathetic activity, and digitalis has inotropic effects. Newer medications target vasodilation and myosin activation to improve heart efficiency while lowering energy requirements. Combination therapy, following an assessment of cardiac function and volume status, is the most effective strategy to heart failure care.
CLASSIFICATION OF H1 ANTIHISTAMINICS-
FIRST GENERATION ANTIHISTAMINICS-
1)HIGHLY SEDATIVE-DIPHENHYDRAMINE,DIMENHYDRINATE,PROMETHAZINE,HYDROXYZINE 2)MODERATELY SEDATIVE- PHENARIMINE,CYPROHEPTADINE, MECLIZINE,CINNARIZINE
3)MILD SEDATIVE-CHLORPHENIRAMINE,DEXCHLORPHENIRAMINE
TRIPROLIDINE,CLEMASTINE
SECOND GENERATION ANTIHISTAMINICS-FEXOFENADINE,
LORATADINE,DESLORATADINE,CETIRIZINE,LEVOCETIRIZINE,
AZELASTINE,MIZOLASTINE,EBASTINE,RUPATADINE. Mechanism of action of 2nd generation antihistaminics-
These drugs competitively antagonize actions of
histamine at the H1 receptors.
Pharmacological actions-
Antagonism of histamine-The H1 antagonists effectively block histamine induced bronchoconstriction, contraction of intestinal and other smooth muscle and triple response especially wheal, flare and itch. Constriction of larger blood vessel by histamine is also antagonized.
2) Antiallergic actions-Many manifestations of immediate hypersensitivity (type I reactions)are suppressed. Urticaria, itching and angioedema are well controlled.3) CNS action-The older antihistamines produce variable degree of CNS depression.But in case of 2nd gen antihistaminics there is less CNS depressant property as these cross BBB to significantly lesser extent.
4) Anticholinergic action- many H1 blockers
in addition antagonize muscarinic actions of ACh. BUT IN 2ND gen histaminics there is Higher H1 selectivitiy : no anticholinergic side effects
- Video recording of this lecture in English language: https://youtu.be/RvdYsTzgQq8
- Video recording of this lecture in Arabic language: https://youtu.be/ECILGWtgZko
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
There are a wide variety of vectors used to deliver DNA or oligo nucleotides into mammalian cells, either in vitro or in vivo.
The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Spark streaming provides stream processing functionality as an abstraction over core Spark. It processes data in micro-batches, where streaming data is buffered for a given interval and then processed as RDDs by core Spark. The processing time of each micro-batch must be less than the batch interval to avoid bottlenecks. Performance can be tuned by parallelizing data consumption from sources like Kafka, and balancing Spark partitions for parallel processing with available cores.
There are several types of shopping malls categorized based on their size, offerings, target customers, and location. Fashion/specialty centers are smaller high-end malls catering to wealthy customers within 5-15 miles. Community centers are larger than neighborhood centers, have discount department stores and apparel stores, and serve areas within 3-6 miles. Lifestyle centers combine retail with leisure amenities, have a cinema as a major tenant, and are located in affluent suburbs.
This document discusses distributed system models and enabling technologies for scalable computing over the Internet. It covers the evolution of computing from centralized to distributed models utilizing multiple computers over the Internet. Key topics include high-performance computing, high-throughput computing, different levels of parallelism, innovative applications, and new paradigms like the Internet of Things. Computer clusters, virtualization, and their design are also summarized.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Congestive Heart failure is caused by low cardiac output and high sympathetic discharge. Diuretics reduce preload, ACE inhibitors lower afterload, beta blockers reduce sympathetic activity, and digitalis has inotropic effects. Newer medications target vasodilation and myosin activation to improve heart efficiency while lowering energy requirements. Combination therapy, following an assessment of cardiac function and volume status, is the most effective strategy to heart failure care.
CLASSIFICATION OF H1 ANTIHISTAMINICS-
FIRST GENERATION ANTIHISTAMINICS-
1)HIGHLY SEDATIVE-DIPHENHYDRAMINE,DIMENHYDRINATE,PROMETHAZINE,HYDROXYZINE 2)MODERATELY SEDATIVE- PHENARIMINE,CYPROHEPTADINE, MECLIZINE,CINNARIZINE
3)MILD SEDATIVE-CHLORPHENIRAMINE,DEXCHLORPHENIRAMINE
TRIPROLIDINE,CLEMASTINE
SECOND GENERATION ANTIHISTAMINICS-FEXOFENADINE,
LORATADINE,DESLORATADINE,CETIRIZINE,LEVOCETIRIZINE,
AZELASTINE,MIZOLASTINE,EBASTINE,RUPATADINE. Mechanism of action of 2nd generation antihistaminics-
These drugs competitively antagonize actions of
histamine at the H1 receptors.
Pharmacological actions-
Antagonism of histamine-The H1 antagonists effectively block histamine induced bronchoconstriction, contraction of intestinal and other smooth muscle and triple response especially wheal, flare and itch. Constriction of larger blood vessel by histamine is also antagonized.
2) Antiallergic actions-Many manifestations of immediate hypersensitivity (type I reactions)are suppressed. Urticaria, itching and angioedema are well controlled.3) CNS action-The older antihistamines produce variable degree of CNS depression.But in case of 2nd gen antihistaminics there is less CNS depressant property as these cross BBB to significantly lesser extent.
4) Anticholinergic action- many H1 blockers
in addition antagonize muscarinic actions of ACh. BUT IN 2ND gen histaminics there is Higher H1 selectivitiy : no anticholinergic side effects
- Video recording of this lecture in English language: https://youtu.be/RvdYsTzgQq8
- Video recording of this lecture in Arabic language: https://youtu.be/ECILGWtgZko
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
There are a wide variety of vectors used to deliver DNA or oligo nucleotides into mammalian cells, either in vitro or in vivo.
The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
Allopurinol, a uric acid synthesis inhibitor acts by inhibiting Xanthine oxidase competitively as well as non- competitively, Whereas Oxypurinol is a non-competitive inhibitor of xanthine oxidase.
Can Traditional Chinese Medicine Treat Blocked Fallopian Tubes.pptxFFragrant
There are many traditional Chinese medicine therapies to treat blocked fallopian tubes. And herbal medicine Fuyan Pill is one of the more effective choices.
BBB and BCF
control the entry of compounds into the brain and
regulate brain homeostasis.
restricts access to brain cells of blood–borne compounds and
facilitates nutrients essential for normal metabolism to reach brain cells
Wavefront-LASIK (Custom LASIK) - The Latest Advance in Laser Eye Surgery - Stanford Eye Laser Center
1. Wavefront-LASIK (Custom LASIK) - The Latest Advance in
Laser Eye Surgery - Stanford Eye Laser Center
Now you have more options than ever before
Wavefront-LASIK (Custom LASIK)
The Latest in Laser Eye Surgery
Custom LASIK is the most advanced laser technology available. Custom LASIK laser treatments are
based upon the unique visual characteristics of your eye. Up until now, with glasses, contacts and
conventional LASIK surgery, corrections were quite similar for each type of prescription. Custom
LASIK involves measuring the eye from front to back with a special laser, using what's called
"wavefront" technology, to create a three-dimensional (3-D) image of the eye. The information
contained in the wavefront-map guides the laser in customizing the treatment to your individual
visual system.
Possible Benefits of Custom LASIK
Custom LASIK wavefront technology is revolutionary because it has the potential to improve not only
the quantity of your vision (i.e. the visual acuity measured by the standard 20/20 Snellen eye chart),
but also the quality of how well you can see (i.e. visual acuity measured in terms of contrast
sensitivity and fine vision). This may translate into a reduced risk of post-LASIK untoward side-
effects, such as difficulty with night vision.
How much you see depends on what lower-order and higher-order aberrations you have; lower-order
aberrations are also called refractive errors (i.e nearsightedness, farsightedness and astigmatism).
Conventional LASIK treats these lower-order aberrations. How well you see can also depends on
what higher-order aberrations you have; higher-order aberrations are irregularities other than
refractive errors, and can cause such problems as decreased contrast sensitivity or night vision,
glare, shadows and halos. Higher-order aberrations do not always affect vision. Custom LASIK has
the potential to treat both lower- and higher-order aberrations. Some of the potential advantages of
wavefront LASIK are:
· Potentially a greater chance of achieving 20/20 vision without glasses
· Potentially a greater chance of achieving better than 20/20 vision
· A potential reduction in the chance of losing best-spectacle corrected vision
· A potential reduction in the chance of losing visual quality or contrast sensitivity
· A potential reduction in the chance of night-vision disturbances
· The potential to use wavefront-LASIK to treat eyes that have previously had laser surgery and
suffer from untoward side-effects (Off-label use of technology)
2. Visx CustomVue WaveScan
Wavefront-guided excimer laser technology
The Visx Wavescan system was the first laser to be approved by the U.S FDA for the treatment of
nearsightedness and astigmatism. The VISX WaveScan system is made up of the Star S4 laser and
the WaveScan wavefront device. The company calls its custom LASIK procedure "CustomVue." The
FDA approval is for eyes with up to -11 diopters of myopia, with or without up to -3 diopters of
astigmatism. Surgeons can, for the lasik eye surgery cost covered insurance first time, measure and
treat visual disorders that previously could not be detected.
In the U.S. FDA clinical trials, 94% of patients who had the Visx CustomVue procedure achieved
20/20 or better vision. The trial participants were four times more likely to say they were "very
satisfied" with their night vision following CustomVue than they were with their night vision with
their glasses or contacts.
How Custom LASIK Works
The surgeon will begin by using the wavefront device to transmit a safe ray of light into your eye.
The light is then reflected back off the posterior portion of the eye, out through the pupil, and into
the abberometry device. The reflected wave of light is received and arranged into a unique pattern
that measures both lower- and higher-order aberrations.
All of these visual measurements are then displayed as a 3-D map, referred to as a wavefront map.
This information is then electronically transferred to the laser, and computer-matched to the eye's
position, enabling the surgeon to customize the LASIK procedure to your unique visual
requirements.
Getting Custom LASIK
Like conventional LASIK, custom LASIK is a surgical procedure and has risks associated with it. It's
important to discuss its applications and potential complications with your eye doctor to determine if
you are a good candidate for this procedure.
3. View an article on Custom LASIK in the Stanford Report ,
and read more about Custom LASIK at the official VISX website for this procedure.
http://eyelaser.stanford.edu/procedures/wavefront-2.html