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Benign and malignant
disease of the vulva
Khalid Sait ( FRCSC)
Gynecological Oncology
Professor
Faculty of Medicine
King Abdulaziz University
Symptoms of Vulvar
Disease
•  Itching
•  Burning
•  Dyspareunia
•  Discharge
•  Bleeding
General Pathology Term.
•  Epidermis
•  Acanthosis
•  Parakeratosis
•  Hyperkeratosis
Vestibular
Micropapillomatosis
General Guide to
Diagnosis
•  White Lesions
•  Red Lesions
•  Brown/Bluish Lesions
White Lesions
•  Vitilligo
•  Nonneoplastic epithelial disorders
Nonneoplastic Epithelial
Disorders - Vulva
•  Squamous cell hyperplasia
•  Lichen Sclerosis
•  Other dermatosis
ISSVD 1987
Lichen Sclerosis
•  Steroid
•  Testesterone
•  Progesterone
Squamous cell
hyperplasia
•  Steroid
Red Lesions
•  Infective
•  Dermatitis
•  Psoriasis
•  Pagets
•  VIN/Ca
HPV - Treatment
•  Observation
•  Podophyllin
•  Trichloroacetic acid
•  Interferon
•  Imiquimod ( Aldara)
•  Excision /Laser
Brownish/Bluish Lesions
•  VIN
•  Naevi/Melanoma
•  Carcinoma
Key Points
•  Inspection/ Palpation
•  Biopsy prior to treatment
•  Medical therapy for majority of
benign lesions

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