This document discusses benign and malignant diseases of the vulva. It begins by outlining common symptoms of vulvar diseases such as itching, burning, and bleeding. It then provides an overview of the general pathology and terminology used to describe vulvar diseases. The document categorizes vulvar lesions as white, red, or brown/bluish and discusses specific conditions that present with each color, including vitiligo, lichen sclerosis, squamous cell hyperplasia, infections, dermatitis, and various precancers and cancers. Treatment options are provided for some conditions like HPV. Throughout, it emphasizes the importance of inspection, palpation, biopsy prior to treatment, and using medical therapy for benign lesions.

1. Benign and malignant
disease of the vulva
Khalid Sait ( FRCSC)
Gynecological Oncology
Professor
Faculty of Medicine
King Abdulaziz University

2. Symptoms of Vulvar
Disease
• Itching
• Burning
• Dyspareunia
• Discharge
• Bleeding

4. General Pathology Term.
• Epidermis
• Acanthosis
• Parakeratosis
• Hyperkeratosis

17. Vestibular
Micropapillomatosis

19. General Guide to
Diagnosis
• White Lesions
• Red Lesions
• Brown/Bluish Lesions

20. White Lesions
• Vitilligo
• Nonneoplastic epithelial disorders

22. Nonneoplastic Epithelial
Disorders - Vulva
• Squamous cell hyperplasia
• Lichen Sclerosis
• Other dermatosis
ISSVD 1987

25. Lichen Sclerosis
• Steroid
• Testesterone
• Progesterone

28. Squamous cell
hyperplasia
• Steroid

33. Red Lesions
• Infective
• Dermatitis
• Psoriasis
• Pagets
• VIN/Ca

41. HPV - Treatment
• Observation
• Podophyllin
• Trichloroacetic acid
• Interferon
• Imiquimod ( Aldara)
• Excision /Laser

51. Brownish/Bluish Lesions
• VIN
• Naevi/Melanoma
• Carcinoma

57. Key Points
• Inspection/ Palpation
• Biopsy prior to treatment
• Medical therapy for majority of
benign lesions