Virus
Virus
Laurence N. Ruedas
Advanced Topic in Biology for Teachers
MATS 305
V I R U S
-Non cellular infectious particles
made up of genetic material
packaged in a protein coat that
can invade living cells.
-Comes from the Latin word “virus”
which means “poison”
Are Viruses Living or
Non Living?
Viruses are Non Living
-they are acellular, that is, they contain
no cytoplasm or cellular organelles.
-They carry out no metabolism on
their own and must replicate using
the host cell's metabolic machinery.
-The vast majority of viruses possess
either DNA or RNA but not both.
Viruses are Living
-They reproduce at a fantastic rate,
but only in living host cells.
-They can mutate
Adolf Mayer
Martinus Beijerinck
Structure of virus
DID YOU KNOW THAT . . . .
The tiniest viruses are
only 20 nm in
diameter while the
largest known virus is
1500 nm
Wendell Stanley
Viruses could be
crystallized
It is an infectious
particle consisting of
one or more
molecules of a nucleic
DNA Virus RNA Virus
VIRAL GENOMES
Genomes are usually organized
as a single linear or circular
molecule of nucleic acid.
smallest virus
has 3 genes
(FMDV)
largest virus has
hundred to 2,000
genes (megavirus)
Capsids and Envelopes
Capsid
- protein shell enclosing the
viral genome
-Made up of large number of
large number of protein sub-
units called capsomeres
Capsids and Envelopes
Capsid
- protein shell enclosing the
viral genome
-Made up of large number of
large number of protein sub-
units called capsomeres
Capsids and Envelopes
Viral Envelopes
-Membranous envelope that
surrounds the capsids which
helps viruses in infecting their
host.
-Derived from the membranes of
the host cell; contains
phospholipids and membrane
Bacteriophages
Viruses that infect bacteria
HOST SPECIFICATION
HOST SPECIFICATION
‱All kingdoms can be infected by
viruses
‱Viruses are kingdom specific but
they may or may not be species
specific
‱Spread is specific to the type of virus
VIRAL REPLICATION
VIRAL REPLICATION
Viruses lack metabolic enzymes
and equipment for making
proteins, such as ribosomes.
THEY CAN ONLY REPLICATE
WITHIN A HOST
SIMPLIFIED
VIRAL REPLICATIVE
CYCLES
VIRAL REPLICATIVE CYCLES
LYTIC CYCLE
LYSOGENIC CYCLE
Lytic cycle
A phage replicative cycle
that culminates in death
of the host cell
Virulent phage
A phage that
replicates only by a
LYTIC CYCLE
LYTIC CYCLE
LySOGENIC CYCLE
A phage replicative cycle
that allows replication
without destroying the
host.
Temperate phage
A phage capable of using
both modes of replicating
LYSOGENIC CYCLE
LYSOGENIC CYCLE
Thank you !!!

Virus.pptx