Platelet and coagulation post graduate lecture Monkez M Yousif
This lecture is prepared for postgraduate students in Internal medicine. It presents a physiologic and basic background of the process of homeostasis followed by a practical approach to diagnosis and brief information of different causes of bleeding disorders
Platelet and coagulation post graduate lecture Monkez M Yousif
This lecture is prepared for postgraduate students in Internal medicine. It presents a physiologic and basic background of the process of homeostasis followed by a practical approach to diagnosis and brief information of different causes of bleeding disorders
Hemostasis, Coagulation, Intrinsic, Extrinsic & common Pathways of Clotting, Common bleeding disorders & their investigations, BT, CT, PT, APTT, TT, Blood & its products, Blood transfusion & its complication.
Hello Docs ! My name is Maharshika It's my small presentation on hemorrhagic syndromes, hemostasis and It's Disorder i hope you guys likes it. Please like it and share it and keep studying 🙂
Hemostasis
Seminar Prepared by :-
Mohammed Saadi
Mohammed Musa
Hussein Jassam
Mahmoud Ahmed
Internal Medicine
College of Medicine - University of Kirkuk
Hemostasis, Coagulation, Intrinsic, Extrinsic & common Pathways of Clotting, Common bleeding disorders & their investigations, BT, CT, PT, APTT, TT, Blood & its products, Blood transfusion & its complication.
Hello Docs ! My name is Maharshika It's my small presentation on hemorrhagic syndromes, hemostasis and It's Disorder i hope you guys likes it. Please like it and share it and keep studying 🙂
Hemostasis
Seminar Prepared by :-
Mohammed Saadi
Mohammed Musa
Hussein Jassam
Mahmoud Ahmed
Internal Medicine
College of Medicine - University of Kirkuk
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Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
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## Introduction to Eating Disorders
Welcome to this comprehensive presentation on Eating Disorders, a critical and often misunderstood area of mental health. This presentation is designed to provide in-depth knowledge and insights into the various aspects of eating disorders, making it valuable for both postgraduate medical aspirants preparing for the INI-CET and the general public seeking to understand these complex conditions.
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3. **Clinical Features and Diagnosis**: Learn about the clinical features, diagnostic criteria, and the importance of early detection.
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---
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8. “group of disorders occouring due to
heriditary deficiency of coagulation”
Characterized by bleeding tendency &
increased clotting time.
Hemoplilia A – 83% cases
* FactorVIII (Classic Hemophilia)
Hemophilia B – 15% cases
* Factor IX (Christmas disease)
Hemophilia C – 2% cases
* Factor XI (PTA deficiency)
9.
10.
11.
12.
13. TESTSTHAT DETECT
DEFECTS INTHP
Bleeding time
Capillary fragility test
Platelet aggregation test
Platelet adhesiveness test
TESTSTHAT DETECT
DEFECTS IN DHP
Clotting time
Prothrombin time
Prothrombin
consumption time
Partial thromboplastin
time (PTT)
Activated partial
thromboplastin time
(aPTT)
Thrombin time
Clot retraction time
14. Time lapse between the skin prick and
arrest of bleeding
Estimated by Duke’s method & Ivy’s
method
Normal values
by Duke’s method – 1-6 min.
by Ivy’s method – 3-6 min.
BT is prolonged in Purpura & normal in
Hemophilia
15. Time between skin prick & formation of
first fibrin thread
Estimated by Capillary tube method & Lee-
White method
Normal values
by capillary tube method is 3-6 min.
by lee-white method is 8-12 min.
Prolonged in hemophila
16. Quick’s one stage method
Commercially available tissue
thromboplastin & CaCl2 is added to
oxalated or citrated plasma – incubated at
37oC
Normal value is 11-16 sec.
Extrinsic system is tested here.(no platelets
involved)
Used to monitor anti-coagulant therapy
Increased in liver failure, vit K deficiency
17. Also known as KCCT – Kaolin cephalin
clotting time.
Detects minute coagulation defects
Normal is 40 sec.
Measures intrinsic pathway
Used to monitor Heparin therapy
Is prolonged in Hemophilia, vWD
18. Measures final step in coagulation i.e,
availability of functional fibrinogen
Normal is 10 sec.
Is prolonged in hypofibrinogenemia,
dysfibrinogenemia, DIC & hepain therapy.
19. Measures time needed for contraction of an
undisturbed clot.
Indicates function & number of platelets
Normally begins within 2 hours and
completed within 24 hours
Is retarded in thrombocytopenia
Clot is small & soft in thromboasthenia