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TUBERCULOSIS
• Tuberculosis is a infectious bacterial disease
caused by mycobacterium tuberculosis - most
commonly affects the lungs.
• Transmitted from persons to person via
droplets from the throat & lungs of people
with the active respiratory disease.
History:-
• Researchers theories that humans first
acquired it in Africa about 5,000 years ago.
• Development diseases depends upon the
closeness of contact .
• Incubation period may be weeks , months or
years.
EPIDEMIOLOGICAL DETERMINANTS
Susceptible
host
pathogen
Conductive
environment
AGENT FACTORS
Agent:-
• Mycobacterium tuberculosis
• -facultative intracellular parasite, ingested by
phagocytes & resistant to intracellular killing.
Source of infection:-
• Human – human case positive for tubercle bacilli
& who has either received no treatment or has
not been fully treated.
• Bovine – infected milk.
Communicability:
• Patients are infective as long as they remain
untreated.
HOST FACTORS
Age:-
• Affects all ages
• In India , 0 – 14 age group – 2%
15 – 24 age group – 20%
Sex:-
• More prevalent in males
Nutrition:-
• Malnutrition- predisposes to TB
immunity-:-
• Man has no inherited immunity against TB
ENVIRONMENTAL / SOCIAL FACTORS
• Poor quality of life
• Poor housing
• Overcrowding
• Population explosion
• Under nutrition
• Lack of education
• Large families & lack of awareness of causes of
illness
MODE OF TRANSMISSION
• Transmitted by droplet infection and droplet
nuclei by sputum positive patients with
pulmonary TB
• Coughing generates the larger number of
droplets of all sizes.
INCUBATION PERIOD
• Time from receipt of infection to the
development of a positive tuberculosis test
range from 3 to 6 weeks.

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Tuberculosis

  • 2. • Tuberculosis is a infectious bacterial disease caused by mycobacterium tuberculosis - most commonly affects the lungs. • Transmitted from persons to person via droplets from the throat & lungs of people with the active respiratory disease.
  • 3. History:- • Researchers theories that humans first acquired it in Africa about 5,000 years ago. • Development diseases depends upon the closeness of contact . • Incubation period may be weeks , months or years.
  • 5. AGENT FACTORS Agent:- • Mycobacterium tuberculosis • -facultative intracellular parasite, ingested by phagocytes & resistant to intracellular killing. Source of infection:- • Human – human case positive for tubercle bacilli & who has either received no treatment or has not been fully treated. • Bovine – infected milk. Communicability: • Patients are infective as long as they remain untreated.
  • 6. HOST FACTORS Age:- • Affects all ages • In India , 0 – 14 age group – 2% 15 – 24 age group – 20% Sex:- • More prevalent in males Nutrition:- • Malnutrition- predisposes to TB immunity-:- • Man has no inherited immunity against TB
  • 7. ENVIRONMENTAL / SOCIAL FACTORS • Poor quality of life • Poor housing • Overcrowding • Population explosion • Under nutrition • Lack of education • Large families & lack of awareness of causes of illness
  • 8. MODE OF TRANSMISSION • Transmitted by droplet infection and droplet nuclei by sputum positive patients with pulmonary TB • Coughing generates the larger number of droplets of all sizes.
  • 9. INCUBATION PERIOD • Time from receipt of infection to the development of a positive tuberculosis test range from 3 to 6 weeks.