1) The document presents a technique for automatically correcting for ion travel time when mass calibrating a single quadrupole mass spectrometer. This allows a single calibration to be used over all mass ranges and scan speeds. 2) By deriving an equation for ion transmission time as a function of mass and scan speed, the mass shift due to varying scan speeds can be calculated and subtracted from acquired data. 3) Empirical testing showed the technique reduced initial mass shifts by at least 85% for all masses and scan speeds, with no residual shift over 0.1 m/z. The combined calibration provides effective mass calibration across an instrument's operating ranges.