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TRANSRADIAL
PERIPHERAL VASCULAR INTERVENTIONS

Cezar Staniloae
NYU Heart and Vascular Institute
Overview
• 1. Why TRA for Peripheral Vascular Interventions?
• 2. Anthropometric Measurements
• 3. Advantages and limitations of TRA in specific
vascular beds
• 4. Current “road blocks” and future needs
Radial Artery is an Ideal Acess Site
•
•
•
•
•
•

Easily accessible even in subjects with severe PVD
Major advantage in terms of bleeding complications1,2
Cannulation benefit for most arterial beds
Improved quality of life3
Time-sparing hemostasis
Same-day discharge

1.

Kiemeneij F, et al. ACCESS Trial. JACC, 1997

2.

RIVAL Trial. Lancet 2011

3.

Cooper CJ, et al. Am Heart J, 1999
ACCUITY - Access
Radial (798)

Femoral (11988)
Anthropometric measurements
R Wrist - R Carotid = 55-65cm
R Wrist - L Carotid (bovine arch) = 55-65cm
Wrist - Subclavian = 50-65cm

L Wrist - Renal A = 90cm
L Wrist - Common Iliac = 105-115cm

L Wrist - CFA = 125-135CM
L Wrist - Popliteal A= 155-170 cm

L Wrist - Foot= 200-230 cm
Subclavian Artery Stenting
Technique
1. Diagnostic imaging: 5Fr MP
2. Exchange for 5-6 Fr 65cm sheath
3. Stable position of the camera - landmarks
4. PTA / Stenting
5. Final imaging
Subclavian Artery Stenting
Ideal guide support

! Useless femoral access
Subclavian Artery Stenting
Catheter in the Aorta

Stenting

Useless catheter from the groin "
Subclavian Artery Stenting
Advantages of Radial Approach
1. Excellent guide support
2. Prevent excessive guide manipulation in the
aortic arch
3. Limited contrast use
4. Absent access-site bleeding complications
5. Immediate ambulation
6. Early discharge
Carotid Artery Stenting
TRA IS the preferred access site for:
1. RICA in the
presence of type
III aortic arch, or
severely disease
arch

2. LICA - when it
arises from the
innominate a
(bovine arch)
LICA in Bovine Arch
Bovine Arch?

1
3
2
4
Carotid Artery Stenting
• RICA in presence of type III aortic arch, or
severely diseased aortic arch
Carotid Artery Stenting
TRA IS NOT the preferred
access site for:
1. LICA - lack of support and
potential for guide prolapse
in the aortic arch
Carotid Artery Stenting
Technical considerations
• 1. Advance the 6Fr Shuttle
sheath in the subclavian a.
• 2. Cannulate the R-CCA (or the
L-CCA when arising from the
innominate artery) using a 5Fr
IM / AR-2 catheter
• 3. Wire the ECA
• 4. Telescope SS over the 5fr IM
Carotid Stenting
Technique
Carotid Artery Stenting
TRA
• Practically, the only approach for bovine arch
• Excellent for the RICA - particularly in type III
arch
• Not preferred for the LICA
Abdominal vessels
Renal Artery Stenting
•

Anatomically, the renal
arteries take off in a
downward fashion therefore, cannulation is
easier from above
Renal Artery Stenting
Technique:
Either 5 Fr / 110 cm Ansel 1 sheath, or
6 fr guiding catheter MP / AR2 / HS
Renal Artery Stenting
• TRA approach - better than femoral:
– In general
– Special circumstances:
• AAA
• Severe PVD
• Steeply angulated renal arteries
Mesenteric Arteries Stenting
• Similar to renal artery stenting
• Usually, better approached from above
• Similar technique:
– 5 Fr / 110 cm Ansel1/2 sheath or,
– 6 Fr guiding catheter (only for the celiac a)
– For SMA, IMA - use 5 Fr /110cm sheath
Iliac Artery Stenting
• L radial is preferred (gain aprox
10 cm)
• 5 Fr / 110 cm introducers
• Any unilateral angioplasty and
stenting can be performed
either with 5Fr compatible selfexpandable stents (Cook
Medical), or balloon expandable
stents
Iliac Artery Stenting
6 Fr 110cm sheath

Post Stenting

330 cm 0.014” Viper wire
Transradial Iliac Stenting
•

80 iliac lesions treated via TRA (28%CTO) or TFA (9%
CTO)

Conclusions:
1. Similar contrast use (238 vs 213 ml)
2. Similar fluoroscopy time (30 vs 27 min)

1.
2.

Shorter time to discharge (14.4 vs 20.9 hrs)
Lower access-site complications (0 vs 7.2%)
Staniloae et al. Cath Cardiovasc interv 2009
Proximal SFA
5 Fr 110 cm sheath

Angioscupt 5.0/40

Edge restenosis post
Viabahn stent
CFA Interventions
• No stent zone
• Frequently - atherectomy + PTA
• Most atherectomy devices require 7 Fr
introducer sheaths
• DB360 - CSI - the only atherectomy
device 6 Fr compatible
CFA Interventions
Left radial access

Right CFA occlusion

Left CFA occlusion
CFA Interventions
Shuttle sheath, 6Fr/ 110cm/ 0.087” via left radial access

CROSSER 14S

Calcified CFA, SFA, PFA
CFA Interventions
DB 360 - 2.0 SC 30
PTA 6.0 mm balloon
CFA Interventions
Post PTA 6.0 at 4 atm

Residual Calcified
Eccentric Stenosis

Residual calcified plaque at the bifurcation
CFA Interventions
Wire in PFA

DB 360 SC

Final result !
New frontiers
SFA / Popliteal
• Currently - severe limitations do to lack
of adequate equipment
• PTA of the very proxymal SFA
• Atherectomy with DB 360 - shaft length
146 cm
TRA is the approach of choice
for stenting of the:
• 1. Subclavian artery
• 2. Right Carotid Artery - in face of a
type 3 arch / diseased arch
• 3. Left Carotid Artery arising from the
innominate artery
• 4. Renal and mesenteric arteries
• 5. Iliac Arteries
Transfemoral access is still
the first choice for:
• 1. Left Carotid Stenting (normal take-off)
• 2. Right Carotid Stenting (normal arch)
• 3. CFA / SFA / BK interventions
Left Radial Artery
•
•
•

1. Gain about 10 cm
2. Avoid the innominate a. tortuosity
3. Avoid catheter manipulation in the aortic arch
Subclavian
1/3 of Carotid

TRA vs TFA

2/3 of Carotids

Renal

CFA

Mesenteric

SFA / Popliteal

Iliac

BK

Transradial

TFA
Limitations of TRA for
Peripheral Interventions
• Lack of adequate transradial training
• Limited equipment
• Paucity of clinical studies
Equipment Shortage
There is a need for:
1. Larger variety of introducer sheaths (90 / 100 / 110 / 125 cm)
2. Ballon catheters with shaft lenghts up to 170-180 cm
3. Longer Guidewires (360-400cm)
4. Stents with shaft lenghts up to 170-180cm
5. CTO / Reentry devices longer and lower profile
TRANSRADIAL
for Vascular Interventions
BASIC EQUIPMENT
Introducer Sheaths: 5 and 6 Fr 90 cm (Terumo); 110 cm (Cook)
Wires: 0.014 / 330 Viper (CSI); 0.035 / 300 Supracor (Abbott); 0.035 hydrophilic coating
(Terumo; Cordis)

Balloons:
up to 5.0 mm diameter - 150 cm shaft (most balloons)
5.5mm and up - longest shaft 135 (Abbott, EV3)

Scoring Balloons:
Angiosculpt - 5 Fr - up to 6.0 - 137-139cm shaft
Cutting Ballons - 6 Fr

Stents:
the only 5 Fr platform - Zilver stent (Cook) -125cm
6 Fr platform - longest shaft 135 (Abbott)
TRANSRADIAL
for Vascular Interventions
ADVANCED EQUIPMENT
•

CTO Devices:
– CROSSER (Bard) - 146 cm shaft - 6Fr (14S)
– Wildcat (Avinger) 6Fr - 110 cm; 5Fr - 140 cm
– Frontrunner (Cordis) - 140 cm

•

Reentry Devices:
– Outback (Cordis) - 6 Fr - 120 cm
– Pioneer (Medtronic) - 6 Fr -

•

Atherectomy:
– DB 360 - 146 cm shaft - all crowns fit in 6 Fr (except 2.25mm)

•

IVUS:
– Volcano - 150 cm
– Atlantis (Boston Scientific) - 135 cm

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Staniloae C - Transradial peripheral vascular interventions

  • 1. TRANSRADIAL PERIPHERAL VASCULAR INTERVENTIONS Cezar Staniloae NYU Heart and Vascular Institute
  • 2. Overview • 1. Why TRA for Peripheral Vascular Interventions? • 2. Anthropometric Measurements • 3. Advantages and limitations of TRA in specific vascular beds • 4. Current “road blocks” and future needs
  • 3. Radial Artery is an Ideal Acess Site • • • • • • Easily accessible even in subjects with severe PVD Major advantage in terms of bleeding complications1,2 Cannulation benefit for most arterial beds Improved quality of life3 Time-sparing hemostasis Same-day discharge 1. Kiemeneij F, et al. ACCESS Trial. JACC, 1997 2. RIVAL Trial. Lancet 2011 3. Cooper CJ, et al. Am Heart J, 1999
  • 4. ACCUITY - Access Radial (798) Femoral (11988)
  • 5. Anthropometric measurements R Wrist - R Carotid = 55-65cm R Wrist - L Carotid (bovine arch) = 55-65cm Wrist - Subclavian = 50-65cm L Wrist - Renal A = 90cm L Wrist - Common Iliac = 105-115cm L Wrist - CFA = 125-135CM L Wrist - Popliteal A= 155-170 cm L Wrist - Foot= 200-230 cm
  • 6. Subclavian Artery Stenting Technique 1. Diagnostic imaging: 5Fr MP 2. Exchange for 5-6 Fr 65cm sheath 3. Stable position of the camera - landmarks 4. PTA / Stenting 5. Final imaging
  • 7. Subclavian Artery Stenting Ideal guide support ! Useless femoral access
  • 8. Subclavian Artery Stenting Catheter in the Aorta Stenting Useless catheter from the groin "
  • 9. Subclavian Artery Stenting Advantages of Radial Approach 1. Excellent guide support 2. Prevent excessive guide manipulation in the aortic arch 3. Limited contrast use 4. Absent access-site bleeding complications 5. Immediate ambulation 6. Early discharge
  • 10. Carotid Artery Stenting TRA IS the preferred access site for: 1. RICA in the presence of type III aortic arch, or severely disease arch 2. LICA - when it arises from the innominate a (bovine arch)
  • 13. Carotid Artery Stenting • RICA in presence of type III aortic arch, or severely diseased aortic arch
  • 14. Carotid Artery Stenting TRA IS NOT the preferred access site for: 1. LICA - lack of support and potential for guide prolapse in the aortic arch
  • 15. Carotid Artery Stenting Technical considerations • 1. Advance the 6Fr Shuttle sheath in the subclavian a. • 2. Cannulate the R-CCA (or the L-CCA when arising from the innominate artery) using a 5Fr IM / AR-2 catheter • 3. Wire the ECA • 4. Telescope SS over the 5fr IM
  • 17. Carotid Artery Stenting TRA • Practically, the only approach for bovine arch • Excellent for the RICA - particularly in type III arch • Not preferred for the LICA
  • 19. Renal Artery Stenting • Anatomically, the renal arteries take off in a downward fashion therefore, cannulation is easier from above
  • 20. Renal Artery Stenting Technique: Either 5 Fr / 110 cm Ansel 1 sheath, or 6 fr guiding catheter MP / AR2 / HS
  • 21. Renal Artery Stenting • TRA approach - better than femoral: – In general – Special circumstances: • AAA • Severe PVD • Steeply angulated renal arteries
  • 22. Mesenteric Arteries Stenting • Similar to renal artery stenting • Usually, better approached from above • Similar technique: – 5 Fr / 110 cm Ansel1/2 sheath or, – 6 Fr guiding catheter (only for the celiac a) – For SMA, IMA - use 5 Fr /110cm sheath
  • 23. Iliac Artery Stenting • L radial is preferred (gain aprox 10 cm) • 5 Fr / 110 cm introducers • Any unilateral angioplasty and stenting can be performed either with 5Fr compatible selfexpandable stents (Cook Medical), or balloon expandable stents
  • 24. Iliac Artery Stenting 6 Fr 110cm sheath Post Stenting 330 cm 0.014” Viper wire
  • 25. Transradial Iliac Stenting • 80 iliac lesions treated via TRA (28%CTO) or TFA (9% CTO) Conclusions: 1. Similar contrast use (238 vs 213 ml) 2. Similar fluoroscopy time (30 vs 27 min) 1. 2. Shorter time to discharge (14.4 vs 20.9 hrs) Lower access-site complications (0 vs 7.2%) Staniloae et al. Cath Cardiovasc interv 2009
  • 26. Proximal SFA 5 Fr 110 cm sheath Angioscupt 5.0/40 Edge restenosis post Viabahn stent
  • 27. CFA Interventions • No stent zone • Frequently - atherectomy + PTA • Most atherectomy devices require 7 Fr introducer sheaths • DB360 - CSI - the only atherectomy device 6 Fr compatible
  • 28. CFA Interventions Left radial access Right CFA occlusion Left CFA occlusion
  • 29. CFA Interventions Shuttle sheath, 6Fr/ 110cm/ 0.087” via left radial access CROSSER 14S Calcified CFA, SFA, PFA
  • 30. CFA Interventions DB 360 - 2.0 SC 30 PTA 6.0 mm balloon
  • 31. CFA Interventions Post PTA 6.0 at 4 atm Residual Calcified Eccentric Stenosis Residual calcified plaque at the bifurcation
  • 32. CFA Interventions Wire in PFA DB 360 SC Final result !
  • 33. New frontiers SFA / Popliteal • Currently - severe limitations do to lack of adequate equipment • PTA of the very proxymal SFA • Atherectomy with DB 360 - shaft length 146 cm
  • 34. TRA is the approach of choice for stenting of the: • 1. Subclavian artery • 2. Right Carotid Artery - in face of a type 3 arch / diseased arch • 3. Left Carotid Artery arising from the innominate artery • 4. Renal and mesenteric arteries • 5. Iliac Arteries
  • 35. Transfemoral access is still the first choice for: • 1. Left Carotid Stenting (normal take-off) • 2. Right Carotid Stenting (normal arch) • 3. CFA / SFA / BK interventions
  • 36. Left Radial Artery • • • 1. Gain about 10 cm 2. Avoid the innominate a. tortuosity 3. Avoid catheter manipulation in the aortic arch
  • 37. Subclavian 1/3 of Carotid TRA vs TFA 2/3 of Carotids Renal CFA Mesenteric SFA / Popliteal Iliac BK Transradial TFA
  • 38. Limitations of TRA for Peripheral Interventions • Lack of adequate transradial training • Limited equipment • Paucity of clinical studies
  • 39. Equipment Shortage There is a need for: 1. Larger variety of introducer sheaths (90 / 100 / 110 / 125 cm) 2. Ballon catheters with shaft lenghts up to 170-180 cm 3. Longer Guidewires (360-400cm) 4. Stents with shaft lenghts up to 170-180cm 5. CTO / Reentry devices longer and lower profile
  • 40. TRANSRADIAL for Vascular Interventions BASIC EQUIPMENT Introducer Sheaths: 5 and 6 Fr 90 cm (Terumo); 110 cm (Cook) Wires: 0.014 / 330 Viper (CSI); 0.035 / 300 Supracor (Abbott); 0.035 hydrophilic coating (Terumo; Cordis) Balloons: up to 5.0 mm diameter - 150 cm shaft (most balloons) 5.5mm and up - longest shaft 135 (Abbott, EV3) Scoring Balloons: Angiosculpt - 5 Fr - up to 6.0 - 137-139cm shaft Cutting Ballons - 6 Fr Stents: the only 5 Fr platform - Zilver stent (Cook) -125cm 6 Fr platform - longest shaft 135 (Abbott)
  • 41. TRANSRADIAL for Vascular Interventions ADVANCED EQUIPMENT • CTO Devices: – CROSSER (Bard) - 146 cm shaft - 6Fr (14S) – Wildcat (Avinger) 6Fr - 110 cm; 5Fr - 140 cm – Frontrunner (Cordis) - 140 cm • Reentry Devices: – Outback (Cordis) - 6 Fr - 120 cm – Pioneer (Medtronic) - 6 Fr - • Atherectomy: – DB 360 - 146 cm shaft - all crowns fit in 6 Fr (except 2.25mm) • IVUS: – Volcano - 150 cm – Atlantis (Boston Scientific) - 135 cm