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Zoltán Ruzsa MD PhD
Financial disclosures
No conflict of interest to declare
Access site selection for lower limb interventions
0
50
100
150
200
250
300
350
1 2 3 4 5 6
Femoral
Radial
Brachial
Dual- Radial + Femoral
Dual- Radial + Transpedal
Dual- Femoral + Transpedal
Access: Foundation of Complex Interventions
• Establish “in-line” flow from
aorta to foot…access is key!
– Retrograde access: Discrete
stenotic disease
– Antegrade CFA access:
Ideal for long occlusive disease; retained
‘pushability,’ torque
– Pedal access: Unsuccessful
antegrade approach (AT/PT)
Access sites for lower limb interventions
Conventional access
• Ad 1. Femoral
• Antegrade femoral
• Cross over
• Distal femoral retro
• Ad 2. Popliteal
• Ad 3. Brachial
• Ad 4. Transpedal
Slender technique
• Ad 5. Radial and Ulnar
• Ad 4. Transpedal
Transpedal punction- dist. ATA
Ultrasound guided puncture
Z. Ruzsa et al. Catheter Cardiovasc Interv. 2014 May 1;83(6):997-1007
Seems to be perfect technique, but…….
• High rate of vascular complications
• Femoral artery bleeding (Incidence ≤6%)
• Retroperitoneal haematoma (Incidence ≤3%)
• Pseudoaneurysm (Incidence by US ≤6%)
• AV fistula (Incidence ≤0.4%)
• Ischemia /emboli (Incidence ≤1%)
• Groin infection (Incidence ≤0.2%)
• Increased hospital stay
• The patients does not prefer the technique
Routine access site selection- iliac
- Multilevel disease
Iliac + Femoral + BTK
- Complex CTO
- Distal stenosis
- Non diseased
CFA
Retrograde
femoral
- EIA stenosis close
to the CFA
- Diseased CFA
Cross over Brachial or radial
access
- Scar
- Bypass
- Stents in the iliac
ostium
- Extreme
angulation
- Extreme
tortuosity
Is there a place for primary radial access for iliac artery intervention ???
Iliac artery intervention- Femoral
Advantages
• Easy
• Fast
• Unlimited use of 6-8F
compatible devices
• Good pushability
Disadvantages
• Vascular complications up to 1-5%
• Late mobilisation
• CFA too close to the lesion
• Cross over is sometimes impossible
• Limited use of closure devices
• Difficult reentry in CTO cases
A. B. C.
Transradial iliac intervention
Pts: 156 consecutive pts
Success: 155 (99.4%)
Cross over: 3.8%
Access site complications: 5.1%
Only minor !!
Learning curve: important role
Left or right side: not different
Sheathless guiding
Coronary SG 8.5 F 100 cm
Internal D: 2.28 mm
External D: 2.8 mm
Peripheral SG 6F 120 cm
Internal D: 2.29 mm
External D: 2.8 mm
Methods: Angioplasty technique
• Medical therapy
– Transradial cocktail (NaHeparin 5000 U and Verapamil
– Per os Aspirin and Clopidogrel
– Heparin up to 100 U/kg
• Punction
– Local anestesia and 5F TR sheath
• Diagnostic angiography
– 125 cm Pig tail catheter
Crossing the aortic arch
Easy aortic
arch
Difficult
aortic arch
Methods:
Angioplasty technique
Cannulation
-8.5 F 100 cm or 6F 120 cm Asahi sheathless
guiding over an long Starter or ES 0.035 GW
-Telescoping technique with a MP 125 cm 5F
catheter in CTO cases
Angioplasty
-„Road map imaging”
-Direct stenting with self expandable or balloon
expandable stent
-Pre and postdilatation
-Final angio
Postop treatment
-Non occlusive pressure bandage
-Immediate mobilisation
CTO recanalisation- case 1
A. B. C.
D. E. F.
CTO recanalisation- case 2
A.
B.
C.
D.
Cross over cases
Subclavian artery CTO Failed reentry Failed reentry
Coronary and iliac lesion (CCS II angina, IC WD:50 m)
Borderline right iliac artery stenosis
Routine access site selection- femoral
- Multilevel disease
Iliac + Femoral + BTK
- Distal stenosis
- Non diseased
CFA
- Popliteal lesion
Anterograde
femoral
- SFA stenosis close
to the CFA
- Diseased CFA
Cross over
possible
Brachial or Radial
No cross over
- Scar
- Bypass
- Stents in the iliac ostium
- Extreme angulation
- Extreme tortuosity
Is there a place for primary radial access
for iliac artery intervention ???
Cross over
- Complex CTO
(failed antegrade)
Popliteal or Transpedal
yes
No
No No
Radial artery access for femoral interventions
Devices
- 6F Short Radial sheath
- Pig Tail catheter
- 300 cm long Starter GW
- 120 cm long Sheathless guiding
- 300 cm long 0.018 Steelcore GW (0.018)
- Balloon with long shaft (180 cm long shaft, long balloons – 5-6
mm x 120-250 mm)
Strategy
- Long balloons and long inflation time (2-3 min)
- Focal stenting (Optimed stent with 180 cm long)
- Stent only in flow limiting dissections
- Alternative access site is the popliteal or transpedal access for
stenting
- For DEB and DES
- Femoral access site only in bail out cases
Limitations
- No DEB available with this shaft size
- No DES available with this shaft size
CIRSE 2016 Abs No 467
PCR 2017
125 consecutive pts
Cross over to femoral 2.4%
Dual access 8%
Successful procedure 92.5%
CTO success 92.5%
Long term MAE: 3.2%
TLR : 1.6%
Femoral artery
intervention- CASE 1
Femoral artery
intervention- CASE 2
Access ??
- iliac stent
- diseases CFA
-Long SFA CTO
-Popliteal CTO
- ATA and ATP occl
TR access
- 6F SG
- V18 GW 300
- Treasure12 300
- Invatec 5x150 180
- Invatec 6x150 180
- Optimed 6x80 180
Peroneal access
- Cook 4F, Terumo 4F
- Progress40 300
- Fox 4x80
Femoropoliteal
intervention
CASE 3
Primary transpedal-
distal lesion, high patient, long arm
Below-the-knee and CLI
Anterograde BTK recanalisation-
wound releated artery
1. Inflow disease
2. Outflow disease
unsuccessful
Retrograde recanalisation
Transpedal access
(ATA, PTA, proneal)
unsuccessful
Kollateral dilatation
(malleolar)
Femoropopliteal
lesion-occlusion
present
Retrograde
recanalisation
Plantar loop technique
Paralell patent artery and plantar
arch present
Peroneal artery and malleolar
collaterals present
- Balloon angioplasty
- Stent in flow
limiting dissections
or recoil
Success
TCT 2011
Good distal run-off
Patent ATA or PTA
BTK and primary transpedal
(radial angio and TP PTA)
60/40 Hgmm 160/80 Hgmm
How to deal with complications ?
• Vascular
• Spasm
• RA perforation
• RA occlusion
• RA pseudoaneurysm
• Brachial artery dissection
• Non vascular
• Fibrous tissue formation
Kozak et. al. CCI 2003
Potential transpedal complications
• Early
• Dissection (Occlusion)
• Thrombosis (Occlusion)
• Vein puncture (AV fistula, vein closure)
• Later
• Athrosclerosis progression ???
• Pseudoaneurysm
• AV fistula
Angiography 2016.01 due to ALI (rad + ped)
Control angiography
Control retrograd angiograpy
Stent graft
3x24 mm
Conclusion
• Transradial iliac artery intervention is safe technique and can be
used as a primary access or secondary access when the femoral
access can not be obtained
• Transradial SFA intervention can be obtained when the femoral
access is not possible or risky. As a primary access site we need
more data…
• Ideal for restenosis and focal lesion
• For popliteal lesions the transradial technique can be used only
in limited cases, but possible from transpedal access
• For patients with multilevel disease and CLI can be used for
treating the inflow arteries with a combination of the transpedal
and popliteal approach
• For isolated BTK lesions the transpedal technique is optimal, but
for complex BTK lesions the antegrade femoral access is the
preferred technique
02 endovascular Ruzsa aimradial20170921 TRA lower limb

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02 endovascular Ruzsa aimradial20170921 TRA lower limb

  • 2. Financial disclosures No conflict of interest to declare
  • 3. Access site selection for lower limb interventions 0 50 100 150 200 250 300 350 1 2 3 4 5 6 Femoral Radial Brachial Dual- Radial + Femoral Dual- Radial + Transpedal Dual- Femoral + Transpedal
  • 4. Access: Foundation of Complex Interventions • Establish “in-line” flow from aorta to foot…access is key! – Retrograde access: Discrete stenotic disease – Antegrade CFA access: Ideal for long occlusive disease; retained ‘pushability,’ torque – Pedal access: Unsuccessful antegrade approach (AT/PT)
  • 5. Access sites for lower limb interventions Conventional access • Ad 1. Femoral • Antegrade femoral • Cross over • Distal femoral retro • Ad 2. Popliteal • Ad 3. Brachial • Ad 4. Transpedal Slender technique • Ad 5. Radial and Ulnar • Ad 4. Transpedal
  • 8. Z. Ruzsa et al. Catheter Cardiovasc Interv. 2014 May 1;83(6):997-1007
  • 9. Seems to be perfect technique, but……. • High rate of vascular complications • Femoral artery bleeding (Incidence ≤6%) • Retroperitoneal haematoma (Incidence ≤3%) • Pseudoaneurysm (Incidence by US ≤6%) • AV fistula (Incidence ≤0.4%) • Ischemia /emboli (Incidence ≤1%) • Groin infection (Incidence ≤0.2%) • Increased hospital stay • The patients does not prefer the technique
  • 10. Routine access site selection- iliac - Multilevel disease Iliac + Femoral + BTK - Complex CTO - Distal stenosis - Non diseased CFA Retrograde femoral - EIA stenosis close to the CFA - Diseased CFA Cross over Brachial or radial access - Scar - Bypass - Stents in the iliac ostium - Extreme angulation - Extreme tortuosity Is there a place for primary radial access for iliac artery intervention ???
  • 11. Iliac artery intervention- Femoral Advantages • Easy • Fast • Unlimited use of 6-8F compatible devices • Good pushability Disadvantages • Vascular complications up to 1-5% • Late mobilisation • CFA too close to the lesion • Cross over is sometimes impossible • Limited use of closure devices • Difficult reentry in CTO cases A. B. C.
  • 12. Transradial iliac intervention Pts: 156 consecutive pts Success: 155 (99.4%) Cross over: 3.8% Access site complications: 5.1% Only minor !! Learning curve: important role Left or right side: not different
  • 13. Sheathless guiding Coronary SG 8.5 F 100 cm Internal D: 2.28 mm External D: 2.8 mm Peripheral SG 6F 120 cm Internal D: 2.29 mm External D: 2.8 mm
  • 14. Methods: Angioplasty technique • Medical therapy – Transradial cocktail (NaHeparin 5000 U and Verapamil – Per os Aspirin and Clopidogrel – Heparin up to 100 U/kg • Punction – Local anestesia and 5F TR sheath • Diagnostic angiography – 125 cm Pig tail catheter
  • 15. Crossing the aortic arch Easy aortic arch Difficult aortic arch
  • 16. Methods: Angioplasty technique Cannulation -8.5 F 100 cm or 6F 120 cm Asahi sheathless guiding over an long Starter or ES 0.035 GW -Telescoping technique with a MP 125 cm 5F catheter in CTO cases Angioplasty -„Road map imaging” -Direct stenting with self expandable or balloon expandable stent -Pre and postdilatation -Final angio Postop treatment -Non occlusive pressure bandage -Immediate mobilisation
  • 17. CTO recanalisation- case 1 A. B. C. D. E. F.
  • 18. CTO recanalisation- case 2 A. B. C. D.
  • 19.
  • 20. Cross over cases Subclavian artery CTO Failed reentry Failed reentry
  • 21. Coronary and iliac lesion (CCS II angina, IC WD:50 m)
  • 22. Borderline right iliac artery stenosis
  • 23. Routine access site selection- femoral - Multilevel disease Iliac + Femoral + BTK - Distal stenosis - Non diseased CFA - Popliteal lesion Anterograde femoral - SFA stenosis close to the CFA - Diseased CFA Cross over possible Brachial or Radial No cross over - Scar - Bypass - Stents in the iliac ostium - Extreme angulation - Extreme tortuosity Is there a place for primary radial access for iliac artery intervention ??? Cross over - Complex CTO (failed antegrade) Popliteal or Transpedal yes No No No
  • 24. Radial artery access for femoral interventions Devices - 6F Short Radial sheath - Pig Tail catheter - 300 cm long Starter GW - 120 cm long Sheathless guiding - 300 cm long 0.018 Steelcore GW (0.018) - Balloon with long shaft (180 cm long shaft, long balloons – 5-6 mm x 120-250 mm) Strategy - Long balloons and long inflation time (2-3 min) - Focal stenting (Optimed stent with 180 cm long) - Stent only in flow limiting dissections - Alternative access site is the popliteal or transpedal access for stenting - For DEB and DES - Femoral access site only in bail out cases Limitations - No DEB available with this shaft size - No DES available with this shaft size CIRSE 2016 Abs No 467 PCR 2017 125 consecutive pts Cross over to femoral 2.4% Dual access 8% Successful procedure 92.5% CTO success 92.5% Long term MAE: 3.2% TLR : 1.6%
  • 27. Access ?? - iliac stent - diseases CFA -Long SFA CTO -Popliteal CTO - ATA and ATP occl TR access - 6F SG - V18 GW 300 - Treasure12 300 - Invatec 5x150 180 - Invatec 6x150 180 - Optimed 6x80 180 Peroneal access - Cook 4F, Terumo 4F - Progress40 300 - Fox 4x80 Femoropoliteal intervention CASE 3
  • 28. Primary transpedal- distal lesion, high patient, long arm
  • 29. Below-the-knee and CLI Anterograde BTK recanalisation- wound releated artery 1. Inflow disease 2. Outflow disease unsuccessful Retrograde recanalisation Transpedal access (ATA, PTA, proneal) unsuccessful Kollateral dilatation (malleolar) Femoropopliteal lesion-occlusion present Retrograde recanalisation Plantar loop technique Paralell patent artery and plantar arch present Peroneal artery and malleolar collaterals present - Balloon angioplasty - Stent in flow limiting dissections or recoil Success TCT 2011 Good distal run-off Patent ATA or PTA
  • 30. BTK and primary transpedal (radial angio and TP PTA) 60/40 Hgmm 160/80 Hgmm
  • 31. How to deal with complications ? • Vascular • Spasm • RA perforation • RA occlusion • RA pseudoaneurysm • Brachial artery dissection • Non vascular • Fibrous tissue formation Kozak et. al. CCI 2003
  • 32. Potential transpedal complications • Early • Dissection (Occlusion) • Thrombosis (Occlusion) • Vein puncture (AV fistula, vein closure) • Later • Athrosclerosis progression ??? • Pseudoaneurysm • AV fistula
  • 33. Angiography 2016.01 due to ALI (rad + ped)
  • 34.
  • 35.
  • 37.
  • 39.
  • 40.
  • 42.
  • 43. Conclusion • Transradial iliac artery intervention is safe technique and can be used as a primary access or secondary access when the femoral access can not be obtained • Transradial SFA intervention can be obtained when the femoral access is not possible or risky. As a primary access site we need more data… • Ideal for restenosis and focal lesion • For popliteal lesions the transradial technique can be used only in limited cases, but possible from transpedal access • For patients with multilevel disease and CLI can be used for treating the inflow arteries with a combination of the transpedal and popliteal approach • For isolated BTK lesions the transpedal technique is optimal, but for complex BTK lesions the antegrade femoral access is the preferred technique