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Transgenic AnimalsTransgenic Animals
S.Muzammil - 2nd
Bio-Chemistry
TRANSGENESIS
• To get the new or needed character in the
selected animal, we transfer the targeted
gene into its genome. this is known as
transgenesis.
• The transferred gene is called as transgene.
• An animal that gains new
genetic information fromthe
addition of foreign DNA is
DNA Microinjection
DNA can also be injected directly into the nuclei
of both cultured cells and developing embryo
Transgenic cows are genetically modified
(GM) cows that have an extra gene or extra
inserted in their DNA
Transgenic
cows
Benefits of
Genetically modified
cow
 To create cows that produce milk containing a
human protein called lysozyme.
 To produce milk with the same properties as
human breast milk
 Human milk contains high quantities of key
nutrients that can help to boost the immune
system of babies and reduce the risk of
infections
 Lysozyme is an antimicrobial protein naturally
found in large quantities in human breast milk, it
helps to protect infants from bacterial infection
 Transgenic cows that produce another protein from
human milk called lactoferrin, which helps to
boost the numbers of immune cells in babies
 Third human milk protein called Alpha-
lactalbumin was also produced by the cows
 Also Increasing casein content of milk to increase
cheese production
Transgenic cows with extra
casein
 The milk from casein transgenic cows contained
double the levels of Kappa casein than milk from
control cows
 The milk from transgenic cows had slightly
yellowish tinge when compared with normal milk
MODIFIEDMILKFROM
TRANSGENIC COWS COULDBE
USEDTO:
 Benefit animal health , for example by improving growth
and survival of calves,
 Prevent animal disease such as - mastitis,
 Make milk with human health benefits,
 Assist milk processing into dairy products.
S.MUZAMMIL 2ND
BIO-CHEM
THANK YOU

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Transgenic Animals

  • 2. TRANSGENESIS • To get the new or needed character in the selected animal, we transfer the targeted gene into its genome. this is known as transgenesis. • The transferred gene is called as transgene. • An animal that gains new genetic information fromthe addition of foreign DNA is
  • 3. DNA Microinjection DNA can also be injected directly into the nuclei of both cultured cells and developing embryo
  • 4.
  • 5. Transgenic cows are genetically modified (GM) cows that have an extra gene or extra inserted in their DNA Transgenic cows
  • 6. Benefits of Genetically modified cow  To create cows that produce milk containing a human protein called lysozyme.  To produce milk with the same properties as human breast milk  Human milk contains high quantities of key nutrients that can help to boost the immune system of babies and reduce the risk of infections
  • 7.  Lysozyme is an antimicrobial protein naturally found in large quantities in human breast milk, it helps to protect infants from bacterial infection  Transgenic cows that produce another protein from human milk called lactoferrin, which helps to boost the numbers of immune cells in babies  Third human milk protein called Alpha- lactalbumin was also produced by the cows  Also Increasing casein content of milk to increase cheese production
  • 8. Transgenic cows with extra casein  The milk from casein transgenic cows contained double the levels of Kappa casein than milk from control cows  The milk from transgenic cows had slightly yellowish tinge when compared with normal milk
  • 9.
  • 10. MODIFIEDMILKFROM TRANSGENIC COWS COULDBE USEDTO:  Benefit animal health , for example by improving growth and survival of calves,  Prevent animal disease such as - mastitis,  Make milk with human health benefits,  Assist milk processing into dairy products.

Editor's Notes

  1. Fig 22.13 The production of transgenic animals by microinjection of DNA into fertilized eggs.