Submitted to,
Prof.Dilip kumar P G
HOD,Dept. Of Geology
Govt.college Kottayam
Submitted by,
Sreeraj K Babu
2nd Msc.Geology 4th Sem
Govt.college Kottayam
1
 A trace element is a chemical element whose concentration
is very low(a trace amount).
 In analytical chemistry a trace element is one whose average
concentration is less than 100 parts per million measured in
the atomic account or less than 100 micrograms per gram.
 In Geochemistry a trace element is one whose concentation
is less than 1000ppm or 0.1% of a rocks composition. It is
compaitable with either a liquid or solid phase.
2
 In biochemistry an essential trace element is a dietary element
that is needed in very minute quantities for the proper growth
development and physiology of the organism.
 The dietary elements or essential trace elements are those that
are required to perform vital metabolic activities in organisms.
3
 Essential trace eements in animals include:
Fe – Hemoglobin
Cu - Respiratory pigments
Co - Vitamin B12
Mn and Zn – Enzymes
 Essential trace elements for human body:
cobalt,copper,fluorine,iodine,iron,selenium,chromium,manganez
e and zinc.
4
 Although they are essential. they become toxic at high
concentrations.
 Element such as Ag,As,Cd,Cr,Hg,Ni,Pb and Sn have no
known biological function, with toxic effects even at low
concentration.
 We need nine trace elements to be healthy.
5
 Zinc
 Managanese
 Chromium
 Copper
 Cobalt
 Iodine
 Iron
 Molybdenum
 Selenium
6
 Physicological Functions:
 Protein metabolism
 Lipid metabolism
 Carbohydrate metabolism
 Bone metabolism
Syptomps of defficency state:
 first affecting the face
 Stomatitis,glossitis,alopecia,nail
changes,vomiting,fever,delayedwount healing, dwarfisim,
mental symptoms, taste disorder
7
Symptopms of excess state:
 Relative fe-cu defficency
 Vomiting
 Abnormal
pain,melena,hyperamylasemia,somnolence,hypotension
 Lung edema,diarrhea
 Reduced reproductive function
 Dwarfism
 Anemia
8
Physiological functions:
 Hemopoiesis
 Bone metabolism
 Connective tissue metabolism
Defficency state:
 Anemia
 Leukopenia
 Neutropenia
 Bone changes in children,bone radiolucency,bone cortex thinning
9
Excess state:
 Nausea
 Vomiting,heartburn,hypotension,coma
 Melena
 oliguria
10
Physiological functions:
 Carbohydrate metabolism
 Cholesterol metabolism
 Connective tissue metabolism
 Protein metabolism
Defficency state:
 Abnormal glucose tolerance
 Reduced respiratory quotient
 Weight loss
 Abnormal nitrogen balance Metabolic consciousness disturbance
11
Excess state:
 Nausea, vomiting,
 peptic ulcer, CNS disorder, Liver/kidney dysfunction,
 growth retardation
12
Physiological functions:
 Antioxidant action
 Reduced carcinogenicity action
Defficency state:
 Myalgia (lower extremities)
 Cardiomyopathy (myocardial cell collapse, fibrosis)
 Nail bed whitening
13
Excess state:
 Selenosis (alopecia, nail detachment, CNS disorder)
14
Physiological functions:
 Bone metabolism
 Carbohydrate metabolism,Lipid metabolism
 Reproduction,Immunity
Defficency state:
 Reduced serum cholesterol
 Reduced coagulation,Hair reddening
 Dermatitis (miliaria crystallina) Growth retardation
 Increased radiolucency at the epiphyses of long bones
15
Excess state:
 Parkinsonian syndrome
 Impotence, loss of vigor, somnolence, anorexia, edema,
myalgia, headache, excitation, fatigue
 Advanced stage: Extra pyramidal disorder
16
Physiological functions:
 Amino acid metabolism
 Uric acid metabolism
 Sulfuric acid/sulfurousacid metabolism
Defficency state:
 Tachycardia Polypnea
 Night blindness ,Scotoma
 Irritability, Somnolence. Coma
17
Excess state:
 Hyperuricemia
 gout
18
Physiological functions:
 Tissue metabolism
Deficiency state;
 Goiter
 Hypothyroidism
Excess state:
 Goiter, hypothyroidism
 Iodine deficiency was a big problem in the middle of the U.S
until iodine was added to table salt in the 20th century.
19
Physiological functions:
 Hemopoiesis
Defficency state:
 Pernicious anemia
 Methylmalonic acidemia
Excess state:
 Cobalt poisoning
20
Physiological function:
 Hemoglobin and myoglobin.
 RBC transport oxygen from your lungs to the organs and other
tissues.
 Myloglobin transport oxygen to muscle cells.
Excess state:
 Joint pain
 Fatigue
 Weakness
21
 Diabeties
 Impotence
 Heart failure
 Liver failure
Treatement include regularly removing blood from body.
Defficency state:
 Anemia
 Severe blood loss in women during pregnency
22
Trace
element
Mean
daily
intake
“No
adverse
effects” level
(NOAEL)
“Lowest
adverse
effect” level
(LOAEL)
Effective
replenish
ment/
pharmac
ological
dose
Recommende
d dietary
allowance
(RDA)
Reference
dose (RfD) RfD/
RDA
Zinc 7~11 mg 30 mg* 600 mg ~200
mg (immune
functions,
etc.)
9.6 mg 30 mg 3
Copper 1~4mg 9 mg* 10 mg — 1.8 mg 9 mg 5
Chromium
(III)
28~62µg 1,000µg* — 150~1,000µ
g
(diabetes
mellitus,
etc.)
35µg 250µg 7
Selenium 41~168µg 400µg 750µg* ~200µg
(cancer
prevention,
etc.)
55µg 250µg 4.5
Manganese 3~4mg 10 mg* — — 4 mg 10 mg 2.5
Molybdenu
m
135~215µ
g
350µg 7 mg* — 30µg 250µg 8
Iodine 200~30,00
0µg
3,000µg* 23,000µg — 150µg 3,000µg 20
Arsenic 10~34µg 40µg* 700µg — 10–34µg 140µg 4
23
 Chromium is found in small quantities in a wide variety of
foods.-meat,wholegrains,broccoli,potatoes,
apples,bananas,garlic.
 Copper:-organ meats,shellfish,nuts,seeds,cocoa and whole
grains.
 Iodine is found naturally in seafood and plant based foods
grown in iodine rich soils such as the soil found near ocean.
24
 Iron rich foods include organ meats,muscle
meat,poultry,fish,legumes and dark leafy greens.
 Manganese is found in pecans and other nuts,pineapples,sweet
potatoes,seeds,legumes and whole grains.
 Molybdenum found in plant foods especially legumes and nuts
 Selenium –plant based foods such as whole grains,nuts,seeds
and legumes.Brazil nuts contains more selenium
 Zinc-meats,seafoods
25

Trace element ppt

  • 1.
    Submitted to, Prof.Dilip kumarP G HOD,Dept. Of Geology Govt.college Kottayam Submitted by, Sreeraj K Babu 2nd Msc.Geology 4th Sem Govt.college Kottayam 1
  • 2.
     A traceelement is a chemical element whose concentration is very low(a trace amount).  In analytical chemistry a trace element is one whose average concentration is less than 100 parts per million measured in the atomic account or less than 100 micrograms per gram.  In Geochemistry a trace element is one whose concentation is less than 1000ppm or 0.1% of a rocks composition. It is compaitable with either a liquid or solid phase. 2
  • 3.
     In biochemistryan essential trace element is a dietary element that is needed in very minute quantities for the proper growth development and physiology of the organism.  The dietary elements or essential trace elements are those that are required to perform vital metabolic activities in organisms. 3
  • 4.
     Essential traceeements in animals include: Fe – Hemoglobin Cu - Respiratory pigments Co - Vitamin B12 Mn and Zn – Enzymes  Essential trace elements for human body: cobalt,copper,fluorine,iodine,iron,selenium,chromium,manganez e and zinc. 4
  • 5.
     Although theyare essential. they become toxic at high concentrations.  Element such as Ag,As,Cd,Cr,Hg,Ni,Pb and Sn have no known biological function, with toxic effects even at low concentration.  We need nine trace elements to be healthy. 5
  • 6.
     Zinc  Managanese Chromium  Copper  Cobalt  Iodine  Iron  Molybdenum  Selenium 6
  • 7.
     Physicological Functions: Protein metabolism  Lipid metabolism  Carbohydrate metabolism  Bone metabolism Syptomps of defficency state:  first affecting the face  Stomatitis,glossitis,alopecia,nail changes,vomiting,fever,delayedwount healing, dwarfisim, mental symptoms, taste disorder 7
  • 8.
    Symptopms of excessstate:  Relative fe-cu defficency  Vomiting  Abnormal pain,melena,hyperamylasemia,somnolence,hypotension  Lung edema,diarrhea  Reduced reproductive function  Dwarfism  Anemia 8
  • 9.
    Physiological functions:  Hemopoiesis Bone metabolism  Connective tissue metabolism Defficency state:  Anemia  Leukopenia  Neutropenia  Bone changes in children,bone radiolucency,bone cortex thinning 9
  • 10.
    Excess state:  Nausea Vomiting,heartburn,hypotension,coma  Melena  oliguria 10
  • 11.
    Physiological functions:  Carbohydratemetabolism  Cholesterol metabolism  Connective tissue metabolism  Protein metabolism Defficency state:  Abnormal glucose tolerance  Reduced respiratory quotient  Weight loss  Abnormal nitrogen balance Metabolic consciousness disturbance 11
  • 12.
    Excess state:  Nausea,vomiting,  peptic ulcer, CNS disorder, Liver/kidney dysfunction,  growth retardation 12
  • 13.
    Physiological functions:  Antioxidantaction  Reduced carcinogenicity action Defficency state:  Myalgia (lower extremities)  Cardiomyopathy (myocardial cell collapse, fibrosis)  Nail bed whitening 13
  • 14.
    Excess state:  Selenosis(alopecia, nail detachment, CNS disorder) 14
  • 15.
    Physiological functions:  Bonemetabolism  Carbohydrate metabolism,Lipid metabolism  Reproduction,Immunity Defficency state:  Reduced serum cholesterol  Reduced coagulation,Hair reddening  Dermatitis (miliaria crystallina) Growth retardation  Increased radiolucency at the epiphyses of long bones 15
  • 16.
    Excess state:  Parkinsoniansyndrome  Impotence, loss of vigor, somnolence, anorexia, edema, myalgia, headache, excitation, fatigue  Advanced stage: Extra pyramidal disorder 16
  • 17.
    Physiological functions:  Aminoacid metabolism  Uric acid metabolism  Sulfuric acid/sulfurousacid metabolism Defficency state:  Tachycardia Polypnea  Night blindness ,Scotoma  Irritability, Somnolence. Coma 17
  • 18.
  • 19.
    Physiological functions:  Tissuemetabolism Deficiency state;  Goiter  Hypothyroidism Excess state:  Goiter, hypothyroidism  Iodine deficiency was a big problem in the middle of the U.S until iodine was added to table salt in the 20th century. 19
  • 20.
    Physiological functions:  Hemopoiesis Defficencystate:  Pernicious anemia  Methylmalonic acidemia Excess state:  Cobalt poisoning 20
  • 21.
    Physiological function:  Hemoglobinand myoglobin.  RBC transport oxygen from your lungs to the organs and other tissues.  Myloglobin transport oxygen to muscle cells. Excess state:  Joint pain  Fatigue  Weakness 21
  • 22.
     Diabeties  Impotence Heart failure  Liver failure Treatement include regularly removing blood from body. Defficency state:  Anemia  Severe blood loss in women during pregnency 22
  • 23.
    Trace element Mean daily intake “No adverse effects” level (NOAEL) “Lowest adverse effect” level (LOAEL) Effective replenish ment/ pharmac ological dose Recommende ddietary allowance (RDA) Reference dose (RfD) RfD/ RDA Zinc 7~11 mg 30 mg* 600 mg ~200 mg (immune functions, etc.) 9.6 mg 30 mg 3 Copper 1~4mg 9 mg* 10 mg — 1.8 mg 9 mg 5 Chromium (III) 28~62µg 1,000µg* — 150~1,000µ g (diabetes mellitus, etc.) 35µg 250µg 7 Selenium 41~168µg 400µg 750µg* ~200µg (cancer prevention, etc.) 55µg 250µg 4.5 Manganese 3~4mg 10 mg* — — 4 mg 10 mg 2.5 Molybdenu m 135~215µ g 350µg 7 mg* — 30µg 250µg 8 Iodine 200~30,00 0µg 3,000µg* 23,000µg — 150µg 3,000µg 20 Arsenic 10~34µg 40µg* 700µg — 10–34µg 140µg 4 23
  • 24.
     Chromium isfound in small quantities in a wide variety of foods.-meat,wholegrains,broccoli,potatoes, apples,bananas,garlic.  Copper:-organ meats,shellfish,nuts,seeds,cocoa and whole grains.  Iodine is found naturally in seafood and plant based foods grown in iodine rich soils such as the soil found near ocean. 24
  • 25.
     Iron richfoods include organ meats,muscle meat,poultry,fish,legumes and dark leafy greens.  Manganese is found in pecans and other nuts,pineapples,sweet potatoes,seeds,legumes and whole grains.  Molybdenum found in plant foods especially legumes and nuts  Selenium –plant based foods such as whole grains,nuts,seeds and legumes.Brazil nuts contains more selenium  Zinc-meats,seafoods 25