Total parenteral nutrition (TPN) involves delivering nutrients intravenously to a patient who cannot eat or absorb enough nutrients by mouth. TPN provides nutrients like glucose, amino acids, lipids, vitamins and minerals to meet nutritional needs. It is used when the gastrointestinal tract is not functioning or absorbing properly due to issues like bowel obstruction or disease. Common side effects include mouth sores, vision changes and infections, so clean equipment and monitoring is important for safety.