Over the past century, industrialized societies have seen a meteoric rise in the so-called diseases of civilization: obesity, cardiovascular disease, osteoporosis, autoimmune disease and cancer. These disorders are often associated with apparent "deficiencies" in critical nutrients such as vitamins, minerals and hormones. This talk will examine the arguments for and against supplementation, together with the evidence from interventional studies. The focus will be on the supplementation with Vitamin C, Vitamin D, and calcium. I will argue that the case for supplementation as a long-term preventive strategy has not be made, and often overlooks the compensating effects of homeostatic regulation.
AHS13 Stephan Guyenet Insulin and Obesity: Reconciling Conflicting Evidence Ancestral Health Society
The pancreatic hormone insulin regulates the trafficking and metabolism of carbohydrate and fat. Since insulin influences fatty acid flux in fat tissue, and manipulating insulin can influence body fatness, this has raised the possibility that insulin plays a role in common obesity. Two competing hypotheses propose that 1) elevated insulin is a compensatory response to insulin resistance that develops with fat gain, or 2) elevated insulin outpaces insulin resistance and favors fat gain. Each hypothesis appears to be supported by a large amount of evidence. This presentation will outline a framework capable of reconciling this seemingly conflicting evidence.
AHS13 Adele Hite - The Real Paleo Challenge: How a Fad on the Fringe Can Beco...Ancestral Health Society
Adele's AHS13 talk, The Real Paleo Challenge: How a Fad on the Fringe Can Become a Force for Change, may be viewed on our youtube channel:
http://youtu.be/l1r8yF02oc8
For complete schedule, bios, abstracts, please see our website:
http://www.ancestralhealth.org/post/ahs13-detailed-schedule
AHS13 Shilpi Mehta — Nutrition for the Eyes, Brain and Heart: An Eye Doctor's...Ancestral Health Society
Ocular health is strongly connected to systemic body health especially in cardiovascular, neuronal, and inflammatory diseases. The eye is the window to the health of the body and inflammation elsewhere can manifest symptoms in the eye. I suggest an anti-inflammatory Paleolithic inspired diet is likely to improve and possibly prevent ocular diseases such as dry eyes, cataracts, macular degeneration, glaucoma, etc. which have inflammatory origins. I will discuss common ocular conditions that have inflammatory causes, an evolutionary perspective on eye diseases, and offer practical recommendations for food and supplements to optimize eye health, which also help the body, especially the heart and brain.
Is the Paleo Diet really the answer to our dieting woes?
The Paleo diet is just like any other diet where you restrict calories and foods and lose weight. The problem with this is that any restrictive diet can lead to feelings of deprivation. When this happens, the dieter is at risk of falling off the diet wagon and regaining the weight fairly quickly.
Permanent weight loss has to be done differently.
Many clients take bone health for granted until they’re presented with a diagnosis of osteoporosis, often following a fracture. Whether your client is nutrient deficient, concerned about bone health, or diagnosed with a metabolic bone disease, adding the right nutrients to a protocol is paramount.
In her latest webinar, Dr Danielle Crida discusses:
- The importance of bone health
- Consequences of low bone mineral density
- The most important nutrients for bone health and their synergistic roles
- Exercise and lifestyle choices for bone strength
- Supplement and dosing recommendations, introducing our new Ca/Mg/D3/K2/Boron product
AHS13 Alyssa Rhoden — Give Them Grains? Analyzing Approaches to World Hunger Ancestral Health Society
Feeding the world is a compelling problem that is expected to worsen. A proposed solution is to increase the number of available calories by diverting more crops from animal feed to direct human consumption. I analyze this approach, taking into account the types of food that can be produced. The results indicate that current crops are rather poor at delivering nutritious food and that repurposing grains is an unlikely solution to world hunger. I will discuss alternative methods by which we can maximize production of nutritious foods and the importance of the ancestral health community’s involvement in the sustainable agriculture movement.
I created and presented a PowerPoint to those attending the CHIP program at the Walla Walla General Hospital. It was about anti-inflammatory diets and was based on current scholarly research articles
AHS13 Stephan Guyenet Insulin and Obesity: Reconciling Conflicting Evidence Ancestral Health Society
The pancreatic hormone insulin regulates the trafficking and metabolism of carbohydrate and fat. Since insulin influences fatty acid flux in fat tissue, and manipulating insulin can influence body fatness, this has raised the possibility that insulin plays a role in common obesity. Two competing hypotheses propose that 1) elevated insulin is a compensatory response to insulin resistance that develops with fat gain, or 2) elevated insulin outpaces insulin resistance and favors fat gain. Each hypothesis appears to be supported by a large amount of evidence. This presentation will outline a framework capable of reconciling this seemingly conflicting evidence.
AHS13 Adele Hite - The Real Paleo Challenge: How a Fad on the Fringe Can Beco...Ancestral Health Society
Adele's AHS13 talk, The Real Paleo Challenge: How a Fad on the Fringe Can Become a Force for Change, may be viewed on our youtube channel:
http://youtu.be/l1r8yF02oc8
For complete schedule, bios, abstracts, please see our website:
http://www.ancestralhealth.org/post/ahs13-detailed-schedule
AHS13 Shilpi Mehta — Nutrition for the Eyes, Brain and Heart: An Eye Doctor's...Ancestral Health Society
Ocular health is strongly connected to systemic body health especially in cardiovascular, neuronal, and inflammatory diseases. The eye is the window to the health of the body and inflammation elsewhere can manifest symptoms in the eye. I suggest an anti-inflammatory Paleolithic inspired diet is likely to improve and possibly prevent ocular diseases such as dry eyes, cataracts, macular degeneration, glaucoma, etc. which have inflammatory origins. I will discuss common ocular conditions that have inflammatory causes, an evolutionary perspective on eye diseases, and offer practical recommendations for food and supplements to optimize eye health, which also help the body, especially the heart and brain.
Is the Paleo Diet really the answer to our dieting woes?
The Paleo diet is just like any other diet where you restrict calories and foods and lose weight. The problem with this is that any restrictive diet can lead to feelings of deprivation. When this happens, the dieter is at risk of falling off the diet wagon and regaining the weight fairly quickly.
Permanent weight loss has to be done differently.
Many clients take bone health for granted until they’re presented with a diagnosis of osteoporosis, often following a fracture. Whether your client is nutrient deficient, concerned about bone health, or diagnosed with a metabolic bone disease, adding the right nutrients to a protocol is paramount.
In her latest webinar, Dr Danielle Crida discusses:
- The importance of bone health
- Consequences of low bone mineral density
- The most important nutrients for bone health and their synergistic roles
- Exercise and lifestyle choices for bone strength
- Supplement and dosing recommendations, introducing our new Ca/Mg/D3/K2/Boron product
AHS13 Alyssa Rhoden — Give Them Grains? Analyzing Approaches to World Hunger Ancestral Health Society
Feeding the world is a compelling problem that is expected to worsen. A proposed solution is to increase the number of available calories by diverting more crops from animal feed to direct human consumption. I analyze this approach, taking into account the types of food that can be produced. The results indicate that current crops are rather poor at delivering nutritious food and that repurposing grains is an unlikely solution to world hunger. I will discuss alternative methods by which we can maximize production of nutritious foods and the importance of the ancestral health community’s involvement in the sustainable agriculture movement.
I created and presented a PowerPoint to those attending the CHIP program at the Walla Walla General Hospital. It was about anti-inflammatory diets and was based on current scholarly research articles
Nutritional Neuroscience: Thinking Twice about the Foods that Feed your Brain. Rachel V. Gow, PhD
This talk discusses the latest neuroscientific findings on the links between nutrition and mental health, well-being and performance. It provides evidence that specific nutrients are “brain-selective” and can act in comparable ways to pharmaceutical drugs. It also outlines the implications of the change in food production as a result of the agricultural revolution in favor of mass food production and how common nutritional insufficiencies may lead to physical and mental ill-health. The presentation discusses which foods may help optimise brain function with a focus on omega-3 highly unsaturated fatty acids.
Plant-based Eating: Enhancing Health Benefits, Minimizing Nutritional RisksRobin Allen
Learning Objectives
At the end of the session, the participants will be able to:
1. Know there is no single definition of a plant-based diet.
2. Discuss health aspects of vegetarian and vegan diets and quality of evidence supporting health claims.
3. Assess nutritional adequacy/status of vegetarians and/or vegans throughout the life cycle and provide strategies for meeting dietary recommendations for vitamin B12, DHA calcium, and zinc.
Dietitian Shubhra has listed the best Benefits Of Vegan Diet through which we’ll understand how green food is much more beneficial than carnivorous food.
Fat intake US has remained rather stable during the past decades despite many claims. I present here the case based on USDA and NHANES data.
Claiming that fat intake has decreased in US is as silly as advising a dieter: “If you want to follow a low-fat diet just keep your fat intake at the current level and simply increase the consumption of carbs. Then you are on low-fat diet and you will reap all the benefits of the diet”
Dr. Alap Shah from La Grange Family Medicine Residency of Amita Health talks about the importance of plant-based nutrition and tips on billing for it at the 2019 Family Medicine Midwest educational meeting
Nutrition is one of the most important health and lifestyle factors in the determination of health and disease today. This slideshow is about a forgotten way to approach nutrition.
Nutritional Neuroscience: Thinking Twice about the Foods that Feed your Brain. Rachel V. Gow, PhD
This talk discusses the latest neuroscientific findings on the links between nutrition and mental health, well-being and performance. It provides evidence that specific nutrients are “brain-selective” and can act in comparable ways to pharmaceutical drugs. It also outlines the implications of the change in food production as a result of the agricultural revolution in favor of mass food production and how common nutritional insufficiencies may lead to physical and mental ill-health. The presentation discusses which foods may help optimise brain function with a focus on omega-3 highly unsaturated fatty acids.
Plant-based Eating: Enhancing Health Benefits, Minimizing Nutritional RisksRobin Allen
Learning Objectives
At the end of the session, the participants will be able to:
1. Know there is no single definition of a plant-based diet.
2. Discuss health aspects of vegetarian and vegan diets and quality of evidence supporting health claims.
3. Assess nutritional adequacy/status of vegetarians and/or vegans throughout the life cycle and provide strategies for meeting dietary recommendations for vitamin B12, DHA calcium, and zinc.
Dietitian Shubhra has listed the best Benefits Of Vegan Diet through which we’ll understand how green food is much more beneficial than carnivorous food.
Fat intake US has remained rather stable during the past decades despite many claims. I present here the case based on USDA and NHANES data.
Claiming that fat intake has decreased in US is as silly as advising a dieter: “If you want to follow a low-fat diet just keep your fat intake at the current level and simply increase the consumption of carbs. Then you are on low-fat diet and you will reap all the benefits of the diet”
Dr. Alap Shah from La Grange Family Medicine Residency of Amita Health talks about the importance of plant-based nutrition and tips on billing for it at the 2019 Family Medicine Midwest educational meeting
Nutrition is one of the most important health and lifestyle factors in the determination of health and disease today. This slideshow is about a forgotten way to approach nutrition.
AHS13 Paul Ralston — The Effect of Diet on Chronic Spinal Pain Disorders Ancestral Health Society
Despite the high frequency of spinal related pain disorders, few patients or physicians understand or even acknowledge the role nutrition plays in pain perception. This presentation will explain the anatomy of the most common spinal structures responsible for being sources of pain. The lecture will also examine the robust role diet plays in increasing or decreasing the perception of pain.
Miki Ben-Dor — Interdisciplinary Reconstruction of the Paleolithic Diet (AHS13)Ancestral Health Society
Several anthropologist have stated that there were many Paleolithic diets, presumably questioning the meat/fat centric Paleo practice or the ancestral paradigm altogether. A review of recent findings relating to the reconstruction of Paleolithic diets from various scientific areas of enquiry will be presented and likely ratios of animal to plant sourced food will be discussed. It will be argued that despite the apparent variability in Paleolithic diets, valid practical dietary guidance can be gained from their study.
AHS12 Robb Wolf, BS — City Zero: How Markets and Evolution Can Revolutionize ...Ancestral Health Society
Robb Wolf, B.S. presenting at the Ancestral Health Symposium 2012 (AHS12)
City Zero: How Markets and Evolution Can Revolutionize Medicine
Abstract:
An investigation of how markets influence medical innovation and a case history of how the Ancestral Health model has been implemented at the city level.
Bio:
Robb Wolf, a former research biochemist, is the New York Times Best Selling author of The Paleo Solution: The Original Human Diet.
Robb has functioned as a review editor for the Journal of Nutrition and Metabolism, is co-founder of the nutrition and athletic training journal, The Performance Menu, and co-owner of NorCal Strength & Conditioning, one of the Men's Health Top 30 Gyms in America.
Dr. Lassek's talk may be viewed here:
http://www.youtube.com/watch?v=gJhT_ANNy4E
Abstract: One puzzle is why human males have such a strong preference for women with hourglass figures and low weights that can compromise fertility. The second is why slender young women typically have about one third of their weight in body fat, more than bears starting to hibernate, and why human infants are also very fat. Finally, why do women typically gain another twenty pounds or more during their reproductive years? The answer may lie in the roles that fat plays in providing essential fatty acids needed for the growth of a very large brain and in regulating overall fetal growth.
AHS13 Jeffrey Rothschild — Time-restricted Feeding, an Overview of the Curren...Ancestral Health Society
Time-restricted feeding is a method of intermittent fasting which allows ad libitum energy intake within a window of 4-12 hours, inducing a 12-20h daily fasted window. A wide variety of health benefits have been seen in animal and human trials, this presentation will review the current research and suggest practical applications.
AHS13 Grayson Wheatley - What is Optimal Health? Complexity Science, Chaos Th...Ancestral Health Society
An ancestral lifestyle relies on alignment of nutrition, physical activity and sleep for achieving optimal health and well-being. New research in complexity science - a rapidly evolving body of work that studies dynamic networking systems - has cast doubt on the effectiveness of how we measure expected outcomes in health and medicine. Complex systems may better explain human health by focusing not on single data elements as “cause-and-effect” but on the interactions among complex biological systems. The implications of complexity science and chaos theory on leading an ancestral lifestyle and achieving optimal health will be discussed.
ASH13 Scott Hall and Robb Wolf — Evaluation of the Impact of a Paleolithic Di...Ancestral Health Society
Traditional cardiovascular risk factors including cholesterol may not provide the best tools for predicting individuals at risk for future cardiovascular disease and current insulin resistance. Novel and emerging evaluations of lipoproteins may provide a more accurate assessment of future cardiovascular risk. In an observational study of a small group of law enforcement officers, we studied the changes in both traditional and nontraditional risk factors when instructed in a “paleo” diet over 6 months. Overall, we found an encouraging impact on both traditional and nontraditional risk factors over the course of the study. It is proposed that a “paleo” diet supplemented with exercise has a positive effect on cardiovascular risk factors and may be a treatment recommendation for individuals at risk.
In recent years, and partially driven through the Ancestral Health movement, high-intensity interval training (HIIT – in its various guises) has become the training mode de jour. But are we over-prescribing the dose of this training? A review of the current research literature on this suggests that high-intensity interval and sprint-type sessions induce a large amount of fatigue in the autonomic nervous system (ANS). Such ANS fatigue can have detrimental effects ranging from sleep disturbances through to HPA axis and stress-related issues. This session discusses the optimal dose for such forms of intense training.
AHS13 Tony Federico — Processed Foods and Processed Friends: Is Facebook a Ne...Ancestral Health Society
Human beings crave social connection in much the same way that we crave sugary, salty, and fatty foods. In this sense, smartphone enabled social media use parallels the fast food drive-through. Chronic daily use of social media can create dependency and is a threat to emotional and psychological well-being just as over consumption of energy dense foods can lead to diabetes, heart disease, and other diseases of civilization. Moderating the consumption of "processed friends" is just as important as moderating the consumption of processed foods for maintaining and improving total health and wellness.
An overview of science and the scientific method or discipline, to include the principle of falsifiability for scientific propositions. This is then applied to my own years of self experimentation in a context of weight gain/loss and degraded/improved health and fitness.
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Interaction of vitamins. WAQAR-2222.pptx2018n18210
This research paper examines the long-term causal relationship between the quality of education and technological readiness. It focuses on Northern Europe, where the quality of education is strongly supported by government policies and/or a high level of intellectual independence, distinguishable from that in the US and Continental Europe (Acemoglu, 2012).
Information technology is increasingly becoming a requirement for the success of modern education. From the point of enrolment in educational institutions up to the point of exit, various technologies are implemented to enhance the smooth running of educational processes such as registration, classroom/online teaching, administration and so on. The implementation of technology in education is aimed at improving the quality, effectiveness, and efficiency of education delivery. Technology, in this regard, covers various teaching and learning aids that are established on the bedrock of an information technology infrastructure (Peña-López, 2016)
. Correspondingly, education combines all available resources to ensure the effective delivery or transfer of knowledge from a teacher to a learner. The end product of education, as suggested by many scholars in education, is “a change in the behavior of the learner” (Mayer-Mihalski & DeLuca, 2014). As education is a key determinant of the social, technological, economic, and political development of any nation, in order to improve and expand access to technology schools are making efforts to increase allocation of technological resources and thus improve the quality of education
Innovation in education can be a major driver behind more equally distributed income among a country’s population. Innovations to improve educational quality can provide long-term benefits in terms of creating a more equal society, which in turn can generate widespread innovative and creative thinking. According to a 2016 OECD report, innovation in educational systems can add value in different ways. First, it can improve learning outcomes and educational processes; for example, personalized learning can be created for each student. Second, education is a means of improving equity and equality; in this sense, innovation can enhance equity in access to education and promote equality in learning outcomes. Third, the educational sector in general introduces changes in response to societal needs. In this context, efficient educational systems should adopt teaching and learning practices that help to foster skills for innovation.
The open educational system in Nordic countries encourages use of technology and a high quality of education. Schleicher (2012) states that good policy in relation to open educational resources can make technology usage more effective in education. According to Schleicher (2012), open platforms can connect teachers experiencing the same difficulties in education and encourage a more collaborative teaching culture, which, in turn, can foster innovation and acq
Did you know custom-formulated dietary supplement can be made product based on plant-based ingredients, including whole foods, extracts and phytochemicals just for you based on Your DNA?.
Current Thoughts on Nutrition With Emphasis on Treating the Cause of Degenera...Visionary Ophthamology
Current Thoughts on Nutrition
With Emphasis on Treating the Cause of Degenerative Eye Disease, Safety Issues, B Vitamins and Essential Fatty Acids and Dry Eyes
Ellen Troyer, MT MA
Similar to AHS13 Todd Becker -The Case Against Nutritional Supplements (AHS13) (20)
AHS13 Tim Gerstmar - It Ain't Your Great-Grandparents World: Environmental To...Ancestral Health Society
Humanity has released approximately 100,000 new chemical compounds into the environment, mostly in the past 100 years. Compounds our bodies have never seen before and weren't designed to deal with. In this talk we will discuss some of the common environmental toxins and how they have been shown to be harmful to human health. We will also discuss: testing methods for quantifying toxicity, how the body detoxifies (the seven organs involved) and provide simple methods audience members can take to reduce their toxic burden, as well as briefly discuss more intensive, physician practices for detoxification for people who need it.
AHS13 Hamilton Stapell — The End of Paleo: Is the Ancestral Health Movement G...Ancestral Health Society
Hamilton's talk may be viewed at http://youtu.be/ArcSIg3cYcw
Complete abstracts along with presenter bios and photos, are available on our website:
http://www.ancestralhealth.org/post/2013-ancestral-health-symposium-ahs13
Abstract:
The current Ancestral Health movement is often thought to be on the verge of going mainstream. Many within the movement believe this would lead to positive health (and financial) outcomes for both individuals and society as a whole. However, the transition from a small, highly-devoted group of adherents to a mass following will be far more difficult than commonly assumed. In addition, this presentation will gauge the current size of the Ancestral Health movement by examining empirical data. It also identifies the two types of individuals that typically go paleo. The key commonality between both groups is a very high level of motivation, which also suggests limited penetration of the Ancestral Health movement in the future.
Depression is an insidious issue in the US and elsewhere. Lifestyle habits that are very different from our ancestral environment may be to blame, and one particularly problematic area is food choice. Depressive symptoms share much in common with the adaptive features of sickness behavior, which is functional when operating in an environment of ancestrally normal immune stressor. Modern diets likely activate the immune system (primarily the inflammatory response) and induce the cascade of adaptive responses that collective make up sickness behavior. Due to their similarities, these may then diagnosed as depression. In this talk, I discuss the links among diet, depression, and inflammation, as well as highlighting some specific dietary components that contribute to this response.
Persistent lack of progress by mainstream (non-evolutionary) medicine suggests evolutionary thinking is necessary for progress, but many examples – involving Weston Price, sleep, depression, weight control, omega-3, acne, depression, and fermented foods -- suggest it is far from sufficient. Evolutionary thinking helps solve health problems because it greatly narrows the possibilities worth study but it does not narrow the possibilities far enough (there is too much uncertainty) to by itself produce practical solutions. For example, evolutionary thinking helped me find a new theory of weight control but I had learn more to find a practical way to lose weight.
Dry Eye Disease (DED) has become a substantial economic burden to industrialized society. It is estimated to cost as much as $18K/year/patient in lost productivity for a total of $55B/year in the United States alone. Severe, untreated dry eye disease can result in significant morbidity and potential loss of vision. The role that diet plays in the inflammation and lipid abnormalities associated with dry eye disease has only recently been discovered and is still not widely accepted in the medical community.
AHS13 Colin Champ — Intermittent Fasting and Carbohydrate Restriction in Canc...Ancestral Health Society
Dietary manipulation, including intermittent fasting, carbohydrate restriction, and ketogenic diets, all ancestral in etiology, appear to increase the efficacy of radiation therapy for cancer treatment in preclinical and clinical trials. Clinical trials incorporating such dietary manipulation are necessary.
AHS13 Anastasia Boulais — Is Sun Worshipping Increasing Your Risk of Melanoma? Ancestral Health Society
Those of us familiar with the evolutionary medicine model have come to question many of the conventional public health recommendations and, along with them, the complete sun avoidance. Dr Anastasia Boulais will describe the delicate balance between the benefits and risks of sun worshipping based on current evidence. The talk will focus on particular patterns of sun exposure which may increase the risk of formation of cutaneous melanoma. Other factors, such as diet, vitamin D status and even training patterns, contributing to that risk will be discussed. Anastasia will conclude with an overview of protective lifestyle factors.
AHS13 Russ Crandall and Paul Jaminet — The Perfectly Healthy Meal: How Ancest...Ancestral Health Society
We examine the principles of recipe and meal design in three approaches – standard Paleo, traditional cuisines, and Perfect Health Diet – to evaluate their similarities and differences. We then compare and contrast how various traditional recipes are implemented in the three approaches, and discuss the relative merits of each approach. Our goal is to answer the question: how can we synthesize the best of each approach to design the most healthful, satisfying, nourishing, delicious food possible?
The Consuming Instinct: What Juicy Burgers, Ferraris, Pornography and Gift Giving Reveal About Human Nature
Gad Saad, Ph.D.
I offer a synopsis of my work in the evolutionary consumption area. This will be achieved by discussing key tenets from my books (The Consuming Instinct and The Evolutionary Bases of Consumption) including that: (1) many consumption acts can be mapped onto four key Darwinian modules (survival, mating, kin selection, and reciprocal altruism); and (2) cultural products (e.g., song lyrics, movie plotlines) are fossils of the human mind that highlight a shared biological-based human nature.
AHS13 Jeff Leighton — The Role of Omega 3 Oils in the Treatment of Chronic In...Ancestral Health Society
Inflammation is associated with virtually all chronic, progressive diseases such as heart disease, vascular disease, asthma, IBS, autoimmune diseases, rheumatoid arthritis, osteoarthritis and even chronic neurological diseases such as Alzheimer’s disease. The signals that induce inflammation are multifactorial. High dose omega 3 has the potential to be as or more effective than pharmaceutical therapies. We will report on a series of omega 3 studies that compared dose response, dose timing, (e.g. once a day or twice a day), and food intake (with or without) in four separate cohorts.
Many people who try an Ancestral Diet don’t get adequate relief for their digestive complaints. A key reason why may be the presence of SIBO. This presentation will discuss symptoms, causes, pathophysiology, diagnosis and treatment of SIBO. A simple breath test can diagnose SIBO and treatments include diet, antibiotics, herbal antibiotics, elemental diet, and probiotics. Central in all treatment of SIBO is a low- carbohydrate, grain-free diet (Specific Carbohydrate Diet, Gut and Psychology Diet, modified Low Fodmaps Diet). Discussion will include why an ancestral diet can benefit digestion and how the SIBO diets differ from standard Paleo/Primal diets.
AHS13 James Steel — An Ancient Perspective on Deconditioning in Low Back Pain Ancestral Health Society
Low back pain (LBP) is a multifactorial issue that is prevalent across most human populations, westernised, rural and indigenous. Deconditioning of the lumbar extensor musculature is a commonly associated factor and has been shown prospectively to be a risk factor for development of LBP. Here an explanation concerning lumbar spine and pelvic anatomic evolution is offered in attempt to integrate these findings. It appears that anatomically modern humans may be predisposed to LBP as a consequence of their evolutionary heritage; the compromise of relatively strong hip/trunk extensors and relatively weak lumbar extensors in combination with a long flexible lumbar spine.
A new theory suggests that acid reflux is caused by carbohydrate malabsorption, small intestinal bacterial overgrowth (SIBO) and microbe-induced gas pressure. The pressure drives acid reflux much like dropping a Mentos in a bottle of coke. Difficult-to-digest Carbohydrates lactose, fructose, resistant starch, fiber and sugar alcohols are most likely to cause malabsorption and symptoms of SIBO-related conditions such as GERD and IBS. A novel calculation called fermentation potential (FP) can measure the gut symptom potential of any food. The low FP approach was successfully tested in a small clinical study in the Boston area.
Peter Attia, MD presenting at the Ancestral Health Symposium 2012 (AHS12)
The Straight Dope on Cholesterol
Abstract:
Cholesterol is one of the most misunderstood molecules in the human body. Much like fire, it can be an essential tool for life, if used properly, or a destructive force if allowed to run amok. In this presentation, Peter Attia will explain how the body creates, moves, and utilizes this vital molecule and how what you eat can tip the balance in your favor. By the end of this talk you'll know more about cholesterol than 99% of the physicians in this country.
Bio:
Peter Attia is the President and co-founder of the Nutrition Science Initiative (NuSI), a California-based 501(c)(3). Peter is also a physician and former McKinsey & Company consultant, where he was a member of both the corporate risk and healthcare practices. Peter earned his M.D. from Stanford University and holds a B.Sc. in mechanical engineering and applied mathematics from Queen's University in Kingston, Ontario, Canada, where he also taught and helped design the calculus curriculum.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
How STIs Influence the Development of Pelvic Inflammatory Disease.pptx
AHS13 Todd Becker -The Case Against Nutritional Supplements (AHS13)
1. The case against
nutritional supplements
Todd Becker
gettingstronger.org
Ancestral Health Symposium
August 17, 2013
2. How did our ancestors thrive without supplements?
Do we really need them?
3. Main Thesis
• For most* people, routine supplementation with
vitamins, minerals and essential fatty acids is
unnecessary and may be counterproductive
• A paleo diet and lifestyle – enhanced by hormesis –
reduces or eliminates the need for supplementation
* Caveat: Short term supplementation may be advisable in cases of
malnutrition, infection, illness, pregnancy or special athletic goals.
4. Outline
• The case for nutritional supplements
• General doubts and objections
• Four examples
– Antioxidants
– Vitamin D
– Calcium
– Omega-3 fatty acids
• The role of hormesis
5. The “paleo” case for nutritional supplements
• Inability to synthesize (vitamin C)
• Inefficient synthesis (vitamin D, omega-3)
• Deficient soils and oceans (minerals, omega-3)
6. General doubts and objections
1. You are not what you eat
You are what your body does with what you eat
This applies to macronutrients
• Excess glucose triglycerides
• Excess protein glucose
• Soluble fiber short chain fatty acids
7. General doubts and objections
1. You are not what you eat
You are what your body does with what you eat
But it also applies to micronutrients
• Malabsorption / excretion (calcium)
• Oxidation (antioxidants, fatty acids)
• Hormone signaling (vitamin D)
• Gene expression (antioxidants, vitamin D)
8. General doubts and objections
2. Nutrients are regulated homeostatically
Exogenous nutrients
can downregulate
endogenous defenses
Examples
– Antioxidants
– Vitamin D
9. The case for antioxidants
• Reactive oxygen species (ROS)
• Can’t synthesize our own vitamin C
• Mega doses suggested for:
– Common cold
– Infections
– Cancer
• Other antioxidants
• Vitamin A
• Vitamin E
• Beta carotene
• Co-Q10
• Alpha lipoic acid
10. Fruits & vegetables
• Health benefits of fruits and vegetables
“ associated” with antioxidant content
?
11. Interventional studies show no benefit
…or even positive harm
AMA (2004):
Meta-analysis 20 studies: C, E beta carotene
> No reduction in CVD, stroke or mortality
Cochrane (2008):
Meta-analysis 67 studies: A, C, E, selenium
> No reduction in mortality
Antioxidants adversely impact exercise!
Ristow (2009):
Vitamins C and E + exercise for 4 weeks
> decreased insulin sensitivity improvement
> reduced antioxidant enzyme levels
Before
exercise
After
exercise
12. What could be going wrong?
• Oxidative “stress” by ROS is not always bad!
• ROS are essential for cell signaling, exercise regulation,
and fighting infection
• Moderate ROS plays a hormetic role in improving
mitochondrial function and upregulating endogenous
antioxidant enzymes
• Antioxidant supplements indiscriminately suppress cell
signaling and downregulate endogenous antioxidant enzymes
13. Endogenous Antioxidants
• The xenobiotic metabolism produces Phase II antioxidant
enzymes to catalytically neutralize chemical toxins:
– Superoxide dismutase (SOD), glutathione reductase (GSH), etc.
• We have co-evolved with certain edible plants to tolerate
modest amounts their polyphenolic “toxins”
• Exposure to these polyphenolic “hormetins” activate the Nrf2
pathway, which produces the endogenous antioxidants
• Hormetins are abundant in pigmented, bitter plants and herbs
• Resveratrol
• Sulforaphane
• Curcumin
• Green tea
14. Supplements vs. Hormetins
Supplements: Antioxidants, minerals,
vitamins and essential fatty acids taken to
correct apparent deficiencies
Hormetins: Spices, herbs, phytonutrients
that activate and strengthen the body’s
endogenous processes of defense, repair,
and tolerance and performance.
Typically hormetins work synergistically
and at low dose
15. Hormetins are agents of hormesis
• Dose-response effect
• Stressors we’ve evolved with
• Activate Defense & repair mechanisms
Edward Calabrese
Suresh Rattan
17. Vitamin C recycling
• Vitamin C (ascorbate) neutralizes oxidants 1-for 1
• Dehydroascorbate (oxidized vitamin C) is readily recycled
thousands of times by endogenous glutathione reductase
• Elevated blood glucose inhibits reuptake and recycling of
dehydroascorbate
ROS
18. Vitamin C storage
• Advocates of mega dose vitamin C note that most primates
(simians) consume 10-20X the RDA of vitamin C
• But humans can efficiently store 10-100X the blood levels of
vitamin C in adrenal, thymus, pituitary and other glands –
enough to ward of scurvy for 3-8 months
Antioxidants: Take home message
• Based upon adequate storage and catalytic recycling, a low
glycemic diet rich in hormetic polyphenols greatly decreases
the daily need for dietary and supplemental vitamin C
19. The case for vitamin D
• From diet or action of UV on skin
• D3 itself is not biologically active
– Requires liver & kidney conversions
– Active form (1,25-D) binds VDR
receptor
• Vitamin D has a dual function
– Low dose: calcium absorption
– Higher dose: immune function (VDR)
20. Correlation and causation
• Low vitamin D3 levels correlate with higher heart
disease, stroke, immune problems, infection & overall
mortality
• But is low vitamin D3 a cause – or a consequence – of
ill health?
– Healthy people may get more sun and exercise,
elevating D3
– People with low D3 often have elevated 1,25-D
• Could 25-D be a mere “biomarker” for health status?
21. Vitamin D risks & questions
• Interventional studies show no benefit, possible harm:
– AMA(2010): Supplements for 5 years in women over 70
produced 15% more falls and 26% more fractures
– NCI (2012): Elevated 25-D linked to aggressive prostate cancer
• Vitamin D is a secosteroid – binds the VDR receptor
– VDR activation dampens the innate immune response
– Provides short term control of infection and autoimmunity
– Long term supplementation with the inactive 25-D might
inhibit 1,25-D action and/or down-regulate VDR function
22. An alternative to vitamin D?
• Can we get the benefits of Vitamin D without the
risks of daily supplementation or sun exposure?
• Hoyer-Hansen studied the pathways activated by the
VDR receptor and noted that
“Autophagy could be a general mediator of the
health-promoting effects of 1,25-(OH)2 (D3).
Accordingly, there is a striking overlap among
the diseases promoted by VD deficiency and
defective autophagy.”
23. Autophagy
• A cellular housecleaning process
– Recycles damaged cytoplasmic matter
– Activated by calorie restriction and exercise
• Regulates the same pathways as vitamin D receptor
– Inhibits mTOR, bcl-1, bcl-2
– Inhibition of carcinogenesis and tuberculosis
Take home message – Vitamin D
• Be wary of supplementing , especially at high doses
• Consider that intermittent fasting and exercise might
activate the same metabolic benefits
24. The case for calcium supplements
• Strong bone formation requires an adequate supply
of calcium
• Deficiencies of calcium (and vitamin D) lead to rickets
and osteoporosis
25. What do interventional studies show?
• Harvard study of 77,761 nurses for 12 years showed
no protection from bone fractures at any dose of
calcium (from dairy or supplements)
• Confirmed by similar studies in Australia and the UK
26. Is calcium getting to where it is needed?
• Blood levels of calcium are tightly regulated
• High levels of vitamin D deplete vitamin K2 and
promote calcification of vascular tissue
• On a standard diet high in grains, phytates bind
calcium, leading to poor absorption
• High blood glucose and insulin levels “leach” calcium
from bones
• In short, taking calcium supplements doesn’t ensure
it will get into bones
27. A better way to build bones
• The solution is not supplementation, but a whole
food diet of “available” calcium, with vits. D, A, K2
• Weight bearing exercise is the most practical way
to stimulate uptake of calcium into bones
28. The case for omega-3 supplements
• EPA and DHA are long chain essential N-3 fatty
acids (EFAs), critical to brain, eye and heart
function
• A low n-3/n-6 ratio has been linked to CVD,
Alzheimer’s, depression, autoimmune disorders
• Most Westerner’s show poor enzymatic
conversion of shorter chain n-3s to the EFAs
• EFAs from consumption of fatty fish is inadequate
Hence, dietary supplementation is recommended
29. Stillwell, William. “The role of polyunsaturated lipids in membrane raft
function”, Scandinavian Journal of Food and Nutrition, 2006; 50 (S2): 107 -113.
30. However EFA supplements have a downside
• A 2013 JAMA study of 2000 men found that men
with the highest blood levels of EPA and DHA had
– 71% higher risk of aggressive prostate cancer
– 44% higher risk of low-grade prostate cancer
• These results replicate earlier findings from a
2011 study
• Under-reported: The increased risk appears
associated only with the more easily oxidized
DHA, not EPA (Nina Bailey)
31. Diet impact on DHA “survival”
• Low carbohydrate diets
dramatically increase “end product”
DHA in muscle membranes
– This improves insulin sensitivity and
inhibits lipogenesis
• This happens despite reduced
enzymatic synthesis of DHA under
carbohydrate restriction
• Low carb diets appear to help
“preserve” DHA by suppressing
ROS-driven lipid peroxidation
From Volek and Phinney, “The Art and Science of Low Carbohydrate Living” (2011)
32. Diet controls fate of EFAs
• DHA is less stable than EPA to lipid peroxidation. The
higher association of DHA with cancer may reflect
this fact.
• Low carb/paleo/non-inflammatory diets result in a
reduced dietary requirement for EFAs because they
are better “preserved” against oxidative damage and
inter-conversion is optimized
• Thus, a non-inflammatory diet may be critical to
getting EFA benefits without the risks posed by
unstable and “damaged” DHA
33. Parting thoughts
• Recommended Daily Allowances for supplements
came from studies of people eating Western diets
• Those diets oxidize nutrients, impair absorption
and recycling, and downregulate endogenous
defenses
• A low insulinogenic, non-inflammatory, whole food
diet greatly improves micronutrient utilization
• Phytonutrients and hormesis can boost
endogenous antioxidants and other defenses
34. For further reading
Related articles on my blog
gettingstronger.org
“The case against antioxidants”
“Why I don’t take vitamin D supplements”
“An alternative to vitamin D supplements”
35. References
Antioxidants
1. Kris-Etherton, Penny M. et al, “Antioxidant vitamin supplements and cardiovascular disease”
Circulation 2004, 110: 637-641.
2. Bjelakovic, Goran et al, “Antioxidant supplements for prevention of mortality in healthy
participants and patients with various diseases”. Cochrane Database of Systematic Reviews 3:
John Wiley & Sons, 2008 and updated 2012.
3. Cheung, M.C. et al, “Antioxidant supplements block the response of HDL to simvastatin-niacin
therapy in patients with coronary artery disease and low HDL” Arterioscler Thromb Vasc Biol,
2001, Aug; 21 (8) 1320-6,
4. Ristow, Michael et al., “Antioxidants prevent health-promoting effects of physical exercise in
humans” PNAS 2009 ; published ahead of print May 11, 2009, doi:10.1073/pnas.0903485106
5. Mendriatta, S. et al. “Erythrocyte ascorbate recycling: antioxidant effects in blood”, Free Radic
Biol Med. 1998, 24 (5): 789-97.
6. Wang, Yaohui et al. “Ascorbate recycling in human neutrophils: Induction by bacteria” Proc. Nat
Acad Sci of U.S.A., 1997, 94 (25) 13816-9.
7. Li, Guolin, “The Positive and Negative Aspects of Reactive Oxygen Species in Sports
Performance”, Ch. 6 in Michael Hamlin et al., ed, Current Issues in Sports and Exercise
Medicine, ISBN 978-953-51, 2013, -1031-6,, 2013
36. References
8. Rountree, Robert, “Beyond Antioxidants: Nutrigenomic Regulation of the Adaptive Stress
Response.” Integrative Practitioner, 2010.
http://www.integrativepractitioner.com/article.aspx?id=17183
Vitamin D
9. Sanders, K.M. et al., “Annual High-Dose Oral Vitamin D and Falls and Fractures in Older
Women: A Randomized Controlled Trial. JAMA 2010, 303 (18) , 1815-1822.
10. Masterjohn, C. “Vitamin D toxicity redefined: vitamin K and the molecular mechanisms” Med
Hypotheses 2007, 8 (5): 1026-34.
11. Agus, David B., The End of Illness. New York: Simon & Schuster, 2011.
12. Hoyer-Hansen, M.D. “Autophagy as a basis for the health-promoting effects of vitamin D”.
Trends in Molecular Medicine (2010) 16:7, 295-302
Calcium
13. Feskanich, D. et al. “Milk, dietary calcium and bone fractures in women: a 12-year prospective
study” Am J Public Health, 1997, 87 (6) 992-7.
37. References
Omega-3 fatty acids
14. Stillwell, William. “The role of polyunsaturated lipids in membrane raft function”, Scandinavian
Journal of Food and Nutrition, 2006; 50 (S2): 107 -113.
15. Brasky, T. M. et al. “Plasma Phospholipid Fatty Acids and Prostate Cancer Risk in the SELECT
Trial” Journal of the National Cancer Institute, Aug 7; 105 (15) 1132-1141, 2013
16. Bailey, Nina. “DHA, not EPA, responsible for omega-3 prostate cancer risk. Igennus Healthcare
Nutrition blog, http://www.igennus-hn.com/dha-not-epa-responsible-for-omega-3-prostate-
cancer-risk-by-dr-nina-bailey/
17. Volek, Jeff S. and Stephen D. Phinney. The Art and Science of Low Carbohydrate Performance: A
Revolutionary Program to Extend your Physical and Mental Performance Envelope.
Createspace.com, Chapter 9 and references, 2012
Hormesis
18. Calabrese, Edward J., and Linda A. Baldwin. "Hormesis: The Dose-Response Revolution." Annu.
Rev. Pharmacol. Toxicol. 43: 175-97, 2003.
19. Rattan, Suresh I and Dino Demirovic. “Hormesis Can and Does Work in Humans.” Dose-
Response. 8(1): 58-63, 2010.