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Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
CHAPTER 19
Nutritional Supplements and Alternative
Medicines
1
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
2
LEARNING OBJECTIVES
 Discussing medical indications for nutritional
supplements.
 Identifying fat-soluble and water-soluble vitamins.
 Identifying minerals that are used as supplements and
for electrolyte replacement.
 Discussing common home remedies used as
alternative medicinal forms.
 Describing the use of herbal medicines.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
3
LEARNING OBJECTIVES (CONT’D.)
 Understanding over-the-counter (OTC) nutritional
supplements and their interactions with therapeutic
prescription medications.
 Describing cultural differences and the use of herbals
and alternative medicines.
 Providing patient education for compliance with
medications used as nutritional supplements and
alternative medicines.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
4
 Intellectual impairment
 Muscle wasting
 Obesity
 Emaciation
 Loss of hair
 Delayed healing of
wounds
NUTRITIONAL IMBALANCE
COMMON SIGNS AND SYMPTOMS
 Nonspecific complaints
 Abnormal bone function
 Neurological damage
 Inability to build, repair
tissue
 Change in energy level
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
NOURISHMENT
The human body requires food, and especially
vitamins, that are not produced by the body.
Vitamins are normally obtained from fluids and plant
and animal products that we ingest.
Nutrients might be “natural,” but they can still have
side effects on the human body when:
 introduced in large amounts
 taken indiscriminately
 interacting with other supplements or drugs
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
6
COMMON SIDE EFFECTS OF VITAMINS,
MINERALS, AND HERBS
 Irritability
 Anorexia
 Headaches, flushing
 Indigestion, nausea, diarrhea, constipation
 Abdominal cramping and pain
 Discolored stools
 Insomnia
 Hypotension
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
7
VITAMINS
 General term for number of organic substances or
nutrients necessary for normal:
 growth
 development
 metabolism
 release of energy from food
 Needed in trace amounts; required amounts vary in
children, elderly, pregnant, or lactating women
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
8
VITAMINS
 Most American diets contain adequate vitamin
amounts.
 Fat-soluble vitamins are stored for long periods.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
9
VITAMINS: PATIENT EDUCATION FOR
COMPLIANCE
 Vitamin supplements - taken in addition to dietary
sources; could be useful during certain times in life
cycle
 Healthy, nonsmoking, nonpregnant adults do not need
vitamin supplements.
 Fortified/enriched foods have synthetic
vitamins added during processing.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
10
VITAMINS: PATIENT EDUCATION FOR
COMPLIANCE
 Overcooking vegetables leads to vitamin loss.
 Over-the-counter vitamins typically have lower vitamin
content than prescription vitamins.
 Humans need 10 to 15 minutes of sunlight exposure
per day, 3 times a week, for normal absorption of
vitamin D.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
11
VITAMINS
 Vitamin A highly teratogenic
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
12
FAT-SOLUBLE VITAMINS
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
13
WATER-SOLUBLE VITAMINS
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
14
WATER SOLUBLE VITAMINS
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
15
VITAMINS
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
16
MINERALS
 Inorganic solid substances
 Usually component of earth’s crust
 Needed in small amounts for body to function
normally
 4% of body weight
 Mineral supplements are needed during rapid growth
periods, for clinical situations (anemia), or during
certain drug therapies (diuretics)
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
17
MINERALS
 Acid—hydrogen ion released in a solution, reacts
with metal to form salts
pH < 7
 Base—combines with hydrogen to form salt
pH > 7 or alkaline
 Salt—any compound of acid and base
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
18
MINERALS
 Electrolytes can conduct electrical charge, form
charged particles (ions).
 Water = solvent; electrolytes = solute
 Together they form an isotonic (0.9%) salt solution.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
19
MAJOR MINERALS
 Calcium (Ca+)
 needed for bone and tooth formation, muscle contraction
and relaxation, blood clotting, nervous system
transmission, insulin secretion
 calcium carbonate (Tums) and Os-Cal good sources
 postmenopausal women need vitamin D for effective
calcium absorption
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
20
MAJOR MINERALS
 Phosphorus (P+)
 needed for bone and tooth formation, energy
 helps in storage of fats and metabolism
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
21
MAJOR MINERALS
 Magnesium (Mg+)
 helps synthesize proteins, stimulates muscle contraction
and nerve transmission, activates enzymes, aids in bone
formation
 supplements found in combinations with other minerals
(calcium)
 Slow Mag, MOM, Epsom salts
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
22
MAJOR MINERALS
 Sodium (Na+)
 regulates body fluid and acid-base balance
 found in table salt
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
23
MAJOR MINERALS
 Potassium (K+)
 maintains cell structure by regulating levels of intracellular
fluid
 regulates muscle function, especially cardiac muscle
 K-Lyte or K-Dur
 Chloride (Cl-)
 serves as buffer, enzyme activator, component of gastric
HCl
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
24
TRACE MINERALS
 Iron (Fe+)
 essential component of blood hemoglobin;
used in antibody formation
 ferrous sulfate darkens stools, causes constipation
 liquid iron preparations should be ingested through a straw
to prevent tooth discoloration
 never mix iron and antacids
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
25
TRACE MINERALS (CONT’D.)
 Zinc (Zn+)
 essential component of DNA and RNA
 necessary for sexual development, wound healing, normal
taste and smell
 Fluorine/Fluorides (Fl)
 protect against dental caries, contribute to bone formation
 present in fluorinated water, tea, seafood
 do not take fluoride drops with milk or dairy products
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
26
USE OF MINERAL SUPPLEMENTS
 Take with care and only under physician advice.
 A healthy person who eats a balanced diet will obtain
sufficient minerals to counteract normal losses of minerals.
 Excessive amounts could easily become toxic,
causing:
 hair loss
 changes in blood, muscles, blood vessels
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
27
ALTERNATIVE MEDICINES
 Products lacking scientific evidence of safety and
efficacy
 some herbal preparations
 copper bracelets for arthritis
 Complementary medicine—alternative techniques
proven effective by scientific research
 acupuncture
 massage therapy
 biofeedback
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
28
HOME AND FOLK REMEDIES
 Treatment devised at home without professional
medical advice
 Passed down from generation to generation
 Questionable therapeutic value
Many home and folk remedies coexist with modern
pharmacological therapy.
In the United States, most cultural groups use some
form of complementary or alternative therapies.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
29
HOME AND FOLK REMEDIES
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
30
SAFETY AND REGULATION OF HERBAL
SUPPLEMENTS
 Considered dietary supplements; not regulated by
FDA
 Always ask patients about their use of herbal
supplements
 Instruct patients to purchase herbs from a reputable
source
 Inform physician of herbal therapy to avoid drug
interactions
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
31
LEADING USES FOR HERBAL PRODUCTS
• Different parts of the herb are used for
medicinal purposes.
Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved.
32
EXAMPLES OF HERBS WITH A POTENTIAL FOR TOXIC
EFFECTS

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Nutritional Supplements and Alternative Medicines

  • 1. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. CHAPTER 19 Nutritional Supplements and Alternative Medicines 1
  • 2. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 2 LEARNING OBJECTIVES  Discussing medical indications for nutritional supplements.  Identifying fat-soluble and water-soluble vitamins.  Identifying minerals that are used as supplements and for electrolyte replacement.  Discussing common home remedies used as alternative medicinal forms.  Describing the use of herbal medicines.
  • 3. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 3 LEARNING OBJECTIVES (CONT’D.)  Understanding over-the-counter (OTC) nutritional supplements and their interactions with therapeutic prescription medications.  Describing cultural differences and the use of herbals and alternative medicines.  Providing patient education for compliance with medications used as nutritional supplements and alternative medicines.
  • 4. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 4  Intellectual impairment  Muscle wasting  Obesity  Emaciation  Loss of hair  Delayed healing of wounds NUTRITIONAL IMBALANCE COMMON SIGNS AND SYMPTOMS  Nonspecific complaints  Abnormal bone function  Neurological damage  Inability to build, repair tissue  Change in energy level
  • 5. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. NOURISHMENT The human body requires food, and especially vitamins, that are not produced by the body. Vitamins are normally obtained from fluids and plant and animal products that we ingest. Nutrients might be “natural,” but they can still have side effects on the human body when:  introduced in large amounts  taken indiscriminately  interacting with other supplements or drugs
  • 6. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 6 COMMON SIDE EFFECTS OF VITAMINS, MINERALS, AND HERBS  Irritability  Anorexia  Headaches, flushing  Indigestion, nausea, diarrhea, constipation  Abdominal cramping and pain  Discolored stools  Insomnia  Hypotension
  • 7. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 7 VITAMINS  General term for number of organic substances or nutrients necessary for normal:  growth  development  metabolism  release of energy from food  Needed in trace amounts; required amounts vary in children, elderly, pregnant, or lactating women
  • 8. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 8 VITAMINS  Most American diets contain adequate vitamin amounts.  Fat-soluble vitamins are stored for long periods.
  • 9. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 9 VITAMINS: PATIENT EDUCATION FOR COMPLIANCE  Vitamin supplements - taken in addition to dietary sources; could be useful during certain times in life cycle  Healthy, nonsmoking, nonpregnant adults do not need vitamin supplements.  Fortified/enriched foods have synthetic vitamins added during processing.
  • 10. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 10 VITAMINS: PATIENT EDUCATION FOR COMPLIANCE  Overcooking vegetables leads to vitamin loss.  Over-the-counter vitamins typically have lower vitamin content than prescription vitamins.  Humans need 10 to 15 minutes of sunlight exposure per day, 3 times a week, for normal absorption of vitamin D.
  • 11. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 11 VITAMINS  Vitamin A highly teratogenic
  • 12. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 12 FAT-SOLUBLE VITAMINS
  • 13. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 13 WATER-SOLUBLE VITAMINS
  • 14. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 14 WATER SOLUBLE VITAMINS
  • 15. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 15 VITAMINS
  • 16. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 16 MINERALS  Inorganic solid substances  Usually component of earth’s crust  Needed in small amounts for body to function normally  4% of body weight  Mineral supplements are needed during rapid growth periods, for clinical situations (anemia), or during certain drug therapies (diuretics)
  • 17. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 17 MINERALS  Acid—hydrogen ion released in a solution, reacts with metal to form salts pH < 7  Base—combines with hydrogen to form salt pH > 7 or alkaline  Salt—any compound of acid and base
  • 18. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 18 MINERALS  Electrolytes can conduct electrical charge, form charged particles (ions).  Water = solvent; electrolytes = solute  Together they form an isotonic (0.9%) salt solution.
  • 19. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 19 MAJOR MINERALS  Calcium (Ca+)  needed for bone and tooth formation, muscle contraction and relaxation, blood clotting, nervous system transmission, insulin secretion  calcium carbonate (Tums) and Os-Cal good sources  postmenopausal women need vitamin D for effective calcium absorption
  • 20. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 20 MAJOR MINERALS  Phosphorus (P+)  needed for bone and tooth formation, energy  helps in storage of fats and metabolism
  • 21. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 21 MAJOR MINERALS  Magnesium (Mg+)  helps synthesize proteins, stimulates muscle contraction and nerve transmission, activates enzymes, aids in bone formation  supplements found in combinations with other minerals (calcium)  Slow Mag, MOM, Epsom salts
  • 22. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 22 MAJOR MINERALS  Sodium (Na+)  regulates body fluid and acid-base balance  found in table salt
  • 23. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 23 MAJOR MINERALS  Potassium (K+)  maintains cell structure by regulating levels of intracellular fluid  regulates muscle function, especially cardiac muscle  K-Lyte or K-Dur  Chloride (Cl-)  serves as buffer, enzyme activator, component of gastric HCl
  • 24. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 24 TRACE MINERALS  Iron (Fe+)  essential component of blood hemoglobin; used in antibody formation  ferrous sulfate darkens stools, causes constipation  liquid iron preparations should be ingested through a straw to prevent tooth discoloration  never mix iron and antacids
  • 25. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 25 TRACE MINERALS (CONT’D.)  Zinc (Zn+)  essential component of DNA and RNA  necessary for sexual development, wound healing, normal taste and smell  Fluorine/Fluorides (Fl)  protect against dental caries, contribute to bone formation  present in fluorinated water, tea, seafood  do not take fluoride drops with milk or dairy products
  • 26. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 26 USE OF MINERAL SUPPLEMENTS  Take with care and only under physician advice.  A healthy person who eats a balanced diet will obtain sufficient minerals to counteract normal losses of minerals.  Excessive amounts could easily become toxic, causing:  hair loss  changes in blood, muscles, blood vessels
  • 27. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 27 ALTERNATIVE MEDICINES  Products lacking scientific evidence of safety and efficacy  some herbal preparations  copper bracelets for arthritis  Complementary medicine—alternative techniques proven effective by scientific research  acupuncture  massage therapy  biofeedback
  • 28. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 28 HOME AND FOLK REMEDIES  Treatment devised at home without professional medical advice  Passed down from generation to generation  Questionable therapeutic value Many home and folk remedies coexist with modern pharmacological therapy. In the United States, most cultural groups use some form of complementary or alternative therapies.
  • 29. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 29 HOME AND FOLK REMEDIES
  • 30. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 30 SAFETY AND REGULATION OF HERBAL SUPPLEMENTS  Considered dietary supplements; not regulated by FDA  Always ask patients about their use of herbal supplements  Instruct patients to purchase herbs from a reputable source  Inform physician of herbal therapy to avoid drug interactions
  • 31. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 31 LEADING USES FOR HERBAL PRODUCTS • Different parts of the herb are used for medicinal purposes.
  • 32. Copyright © 2012, 2009, 2003 by Saunders, an imprint of Elsevier Inc. All rights reserved. 32 EXAMPLES OF HERBS WITH A POTENTIAL FOR TOXIC EFFECTS