This document provides information about Colorado's tobacco prevention program. It discusses the program's mission, costs of tobacco use, smoking rates among different demographic groups, youth smoking rates, strategic goals to reduce tobacco use and exposure to secondhand smoke, priority populations, initiatives including policy work and partnerships, a work plan, and some recent progress made in tobacco prevention efforts.
FDLI - Lesson for the US from other jurisdictions - the United Kingdom -29 Oc...Clive Bates
Presentation on the most significant differences between US and UK/EU regulation of tobacco and vaping products. FDLI Tobacco and Nicotine Products Regulation and Policy Conference
India - Economic Times - Consumer Freedom Conclave - 24 Feb 2022Clive Bates
Tobacco harm reduction: the biggest public health win of the 21st Century?
1. Tobacco harm reduction
2. Risk communication
3. Policymaking
4. Cause of opposition
5. Innovation
Albania National Association of Public health - Harm Reduction ConferenceClive Bates
Seven insights into tobacco harm reduction (20 min version) 20th December 2021.
1.The problem is smoking
2. Smoke-free alternatives
3. Quitting smoking with smoke-free alternatives
4. Health concerns
5. Youth vaping
6. Policy and unintended consequences
7. Innovation (and its enemies)
Nicotina - Reducción de riesgos y daños / Nicotine - Risk and Harm ReductionClive Bates
Presentación en línea para el seminario de políticas en Colombia enfocado en políticas de vapeo y consecuencias no deseadas /
Presentation online for policy seminar in Colombia focussed on vaping policy and unintended consequences
Seven insights into tobacco harm reductionClive Bates
1st Tobacco Harm Reduction Malaysia Scientific Meeting
21 November 2021.
1. The problem is smoking
2. Smoke-free alternatives
3. Quitting smoking with smoke-free alternatives
4. Health concerns
5. Youth vaping
6. Policy and unintended consequences
7. Innovation (and its enemies)
E-cigarette Summit - The New Tobacco Wars - 7 December 2021Clive Bates
The presentation gives my take on the conflict raging in tobacco control. It looks at where things are going wrong in science, risk communication, policy, and youth politics. It then looks at causes: institutional and cultural inertia. And finally, finds hope in the basic processes of innovation.
FDLI - Lesson for the US from other jurisdictions - the United Kingdom -29 Oc...Clive Bates
Presentation on the most significant differences between US and UK/EU regulation of tobacco and vaping products. FDLI Tobacco and Nicotine Products Regulation and Policy Conference
India - Economic Times - Consumer Freedom Conclave - 24 Feb 2022Clive Bates
Tobacco harm reduction: the biggest public health win of the 21st Century?
1. Tobacco harm reduction
2. Risk communication
3. Policymaking
4. Cause of opposition
5. Innovation
Albania National Association of Public health - Harm Reduction ConferenceClive Bates
Seven insights into tobacco harm reduction (20 min version) 20th December 2021.
1.The problem is smoking
2. Smoke-free alternatives
3. Quitting smoking with smoke-free alternatives
4. Health concerns
5. Youth vaping
6. Policy and unintended consequences
7. Innovation (and its enemies)
Nicotina - Reducción de riesgos y daños / Nicotine - Risk and Harm ReductionClive Bates
Presentación en línea para el seminario de políticas en Colombia enfocado en políticas de vapeo y consecuencias no deseadas /
Presentation online for policy seminar in Colombia focussed on vaping policy and unintended consequences
Seven insights into tobacco harm reductionClive Bates
1st Tobacco Harm Reduction Malaysia Scientific Meeting
21 November 2021.
1. The problem is smoking
2. Smoke-free alternatives
3. Quitting smoking with smoke-free alternatives
4. Health concerns
5. Youth vaping
6. Policy and unintended consequences
7. Innovation (and its enemies)
E-cigarette Summit - The New Tobacco Wars - 7 December 2021Clive Bates
The presentation gives my take on the conflict raging in tobacco control. It looks at where things are going wrong in science, risk communication, policy, and youth politics. It then looks at causes: institutional and cultural inertia. And finally, finds hope in the basic processes of innovation.
This presentation was developed for our CLeaR (local government tobacco control standards) assessment in July 2014. It sets out our vision for tobacco control in Hertfordshire, summarises our strategies and current position and identifies our future work including commitment to harm reduction, getting positive gains from e-cigarettes and driving tobacco related harm down
Innovation for Consumers: E-cigarettes and novel tobacco products - Part of t...Clive Bates
Clive Bates presentation at a seminar in the European Parliament organised by Monika Beňová MEP
European Commission DG SANTE - Matus Ferech
Patient Access Partnership - Dr. Stanimir Hasurdjiev
Vaping and tobacco: six things you need to know about harm reductionClive Bates
1. Smoking has not gone away
2. Technologies to obsolete cigarettes
3. Risks and risk (mis)perceptions
4. The public health mechanism and the pleasure principle
5. The youth vaping epidemic – a harder look
6. Policymaking and perverse consequences
Reduced nicotine rule: a terrible idea to be pursued relentlesslyClive Bates
Presentation to FDLI conference 26th October 2017. For more information and full report see: https://www.clivebates.com/fda-wants-to-reduce-nicotine-in-cigarettes-what-could-possibly-go-wrong-and-right/
NYU College of Global Health - E-cigarette seminar - New YorkClive Bates
E-Cigarettes: The Tectonic Shift in Nicotine and Tobacco Consumption: Opportunity or Threat to Saving Lives?
Clive Bates
Friday, October 19, 2018
NYU School of Law, Greenberg Lounge
40 Washington Square South, New York, New York
What's Your LMSs Status? Online Learning Conference 2013 (#olc13) session 504v2Brandon Williams
Here's an updated version of the LMSs Status preso shared initially at the Training Magazine Conference and Expo in Orlando back in Feb. The organizers of their online conference reached out to ask that we present in Chicago, so I updated the deck with new info and relevant stats. Enjoy!
What's Your LMSs Status? Online Learning Conference 2014Brandon Williams
Has your LMS become irrelevant in your greater learning strategy? Are you employees finding it difficult to use? Do administrators find it old and stodgy or want to get rid of it altogether? Take a look at this presentation (originally prepared for Training Magazine's Online Learning Conference in Chicago on September 23, 2014) for some insight into why you may want to keep your LMS around and how you might be able to transform it into a more useful and usable piece of technology in your portfolio.
Please contact me if you have any questions.
This presentation was developed for our CLeaR (local government tobacco control standards) assessment in July 2014. It sets out our vision for tobacco control in Hertfordshire, summarises our strategies and current position and identifies our future work including commitment to harm reduction, getting positive gains from e-cigarettes and driving tobacco related harm down
Innovation for Consumers: E-cigarettes and novel tobacco products - Part of t...Clive Bates
Clive Bates presentation at a seminar in the European Parliament organised by Monika Beňová MEP
European Commission DG SANTE - Matus Ferech
Patient Access Partnership - Dr. Stanimir Hasurdjiev
Vaping and tobacco: six things you need to know about harm reductionClive Bates
1. Smoking has not gone away
2. Technologies to obsolete cigarettes
3. Risks and risk (mis)perceptions
4. The public health mechanism and the pleasure principle
5. The youth vaping epidemic – a harder look
6. Policymaking and perverse consequences
Reduced nicotine rule: a terrible idea to be pursued relentlesslyClive Bates
Presentation to FDLI conference 26th October 2017. For more information and full report see: https://www.clivebates.com/fda-wants-to-reduce-nicotine-in-cigarettes-what-could-possibly-go-wrong-and-right/
NYU College of Global Health - E-cigarette seminar - New YorkClive Bates
E-Cigarettes: The Tectonic Shift in Nicotine and Tobacco Consumption: Opportunity or Threat to Saving Lives?
Clive Bates
Friday, October 19, 2018
NYU School of Law, Greenberg Lounge
40 Washington Square South, New York, New York
What's Your LMSs Status? Online Learning Conference 2013 (#olc13) session 504v2Brandon Williams
Here's an updated version of the LMSs Status preso shared initially at the Training Magazine Conference and Expo in Orlando back in Feb. The organizers of their online conference reached out to ask that we present in Chicago, so I updated the deck with new info and relevant stats. Enjoy!
What's Your LMSs Status? Online Learning Conference 2014Brandon Williams
Has your LMS become irrelevant in your greater learning strategy? Are you employees finding it difficult to use? Do administrators find it old and stodgy or want to get rid of it altogether? Take a look at this presentation (originally prepared for Training Magazine's Online Learning Conference in Chicago on September 23, 2014) for some insight into why you may want to keep your LMS around and how you might be able to transform it into a more useful and usable piece of technology in your portfolio.
Please contact me if you have any questions.
10 provocations on why FDA's regulation of tobacco and nicotine is failing the American public. My presentation to the US E-cigarette Summit 2022 in Washington DC, with bonus content of additional background slides added in.
Circles of San Antonio Community Coalition Staff conducted a presentation for the Prevention Resource Center, Region 8 on why Alcohol is the # 1 drug of concern in San Antonio and Texas.
In 2011, the Chicago Department of Public Health created an Office of Adolescent & School Health. Here's an update presented to the Chicago Board of Health
Barriers and unintended consequences How poor regulation of low-risk alternat...Clive Bates
A shirt presentation to Georgian health experts on the dangers of excessive regulation of safer alternatives to smoking causing perverse unintended consequences.
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Smoking & Tobacco Use
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HomeOffice on Smoking and Health (OSH)How OSH Serves StatesNational Tobacco Control Program FundingState Fact SheetsFunding Opportunity AnnouncementsPublic Health Approaches for Ensuring Quitline CapacityFrequently Asked Questions and AnswersInteragency Committee on Smoking and HealthOverviewMembership RosterMeeting Summaries05/31/2017 [PDF—935 KB]08/23/2016 [PDF—806 KB]12/16/2014 [PDF—542 KB]05/13/2014 [PDF—443 KB]01/29/2013 [PDF—124 KB]Meeting ThemesNewsroomStay ConnectedOrganizationQuit SmokingHow to QuitBenefits of QuittingQuit Smoking ResourcesCessation Materials for State Tobacco Control ProgramsNational Quitline Data WarehouseBasic InformationHealth EffectsCancerHeart Disease and StrokeChronic Obstructive Pulmonary Disease (COPD)Smoking During PregnancySecondhand SmokeSmokeless ProductsElectronic CigarettesAbout Electronic Cigarettes (E-Cigarettes)Quick Facts on the Risks of E-cigarettes for Kids, Teens, and Young AdultsYouth Tobacco PreventionTobacco ProductsTobacco Ingredient ReportingHealthy PeopleTobacco Use Goals and Key AreasLeading Health Indicators and ObjectivesMidcourse ReviewTobacco Use ToolkitOnline ResourcesStay ConnectedContact InformationRelated ResourcesClinician ResourcesGovernment AgenciesOther U.S. OrganizationsInternational OrganizationsTobacco-Related DisparitiesAfrican Americans and Tobacco UseAmerican Indians/Alaska Natives and Tobacco UseAsian Americans, Pacific Islanders, Native Hawaiians and Tobacco UseHispanics/Latinos and Tobacco UseLesbian, Gay, Bisexual, and Transgender Persons and Tobacco UseCigarette Smoking and Tobacco Use Among People of Low Socioeconomic StatusTobacco Use by Geographic RegionTobacco Use Among Adults with Mental and Substance Use DisordersPromising Policies And Practices To Address Tobacco Use By Persons With Mental And Substance Use DisordersNew York Implements Tobacco-Free Campus PoliciesOklahoma Awards Grant Funds to Screen for Tobacco UseHawaii Trains Treatment Providers to Counsel Clients to QuitTexas Provides Free NRT to Treatment ProvidersNew York’s and Oklahoma’s Medicaid Programs Pay for MedicationStates Take More Steps to Quit Smoking for Behavioral Health ConditionsData and StatisticsFast Facts and Fact SheetsSurveysNational Youth Tobacco Survey (NYTS)National Adult Tobacco Survey (NATS)Youth Tobacco Survey (YTS)Alaska Native Adult T.
Ray Baxter from Kaiser Permanente's Community Benefit presented at the Bay Area Open Space Council's 2011 conference. More about the conference here: http://openspacecouncil.org/upload/page.php?pageid=53
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. Top Row:
Dee Thomas –
Enforcement Program Coordinator
Emma Goforth –
Adult Cessation Coordinator
Celeste Schoenthaler –
Unit Manager
Gracie Cash –
Tobacco Program Generalist
Bottom Row:
Jennie Munthali –
Stephanie Walton – Youth Policy Coordinator
Jill Bednarek – Secondhand Smoke Coordinator
Not pictured:
Sharon Tracey – Youth and Young Adult Initiatives Coordinator
Jennifer Schwartz – Tobacco Initiatives Work Lead
3. Tobacco Program Mission
In partnership with communities, youth and
stakeholders, our team provides leadership for
tobacco prevention by promoting and
implementing evidence-based, data-driven
strategies across Colorado.
4.
5. Tobacco use is costly for everyone
Cost to United States economy each year in
healthcare costs and lost productivity:
$193 billion
Cost to Colorado each year in healthcare costs and
lost productivity:
$2.4 billion*
Annual U.S. Medicaid costs due to smoking:
$30.9 billion
Annual Colorado Medicaid costs due to smoking:
$319 million
6. Adult current smoking by demographic group
Cover this blue placeholder Note: * Estimates for education are based on adults aged 20 years and older. Estimates for racial/ethnic groups
with your program logo are based on combined 2009 and 2010 data. Source: CDC Behavioral Risk Factor Surveillance System
8. Tobacco Use in Medicaid Population
~500,000 individuals receive Medicaid each year in CO
40%
35%
30%
25%
20% 38%
15%
10% 18%
5%
0%
Medicaid Colorado Adults
Tobacco Use TABS 2008
9. Middle School & High School Students Ever Smoking-Colorado
100.0%
80.0%
60.0%
2001
2006
40.0%
2008
54.2%
20.0% 43.2%
36.8%
25.7%
16.7% 14.4%
0.0%
Middle School High School
Source: Colorado Healthy Kids Colorado Survey on Tobacco and Health, 2001, 2006, and 2008
10. ~90% of adult smokers first try tobacco before the age of 18†
Each Year in the Unites States…
Approximately 400,000 kids become regular smokers*
6 Million kids will die prematurely from their addiction*
Each Year in Colorado…
4,900 youth become regular smokers*
92,000 kids will die prematurely from smoking*
That is more than twice the entire population of Grand Junction!
† Surgeon General’s Report: Preventing Tobacco Use Among Young People, 1994.
* CDC: Best Practices for Tobacco Control Programs, 2007.
11. 6 out of 10 Colorado high school students attempting to
purchase cigarettes are successful
12.
13. Youth vs. Adult Smokeless Tobacco Use
25.0%
Male Smokeless Tobacco Use
20.0%
15.0%
10.0% 2008
12.9%
5.0% 9.5%
7.3%
4.1% 1.8%
0.0%
High School 18-24 years 25-44 years 45-64 years 65+ years
old old old old
Colorado Healthy Kids Colorado Survey on Tobacco and Health, 2008 & Tobacco
Attitudes and Behavior Survey, 2008
14. Strategic Plan Goals
2020 Goals
1. The cessation success gap affecting low SES youth and adult smokers
decreases by 50 percent
2. A majority of people and health care systems in Colorado recognize
and treat tobacco dependence as a chronic condition
3. A majority of Coloradans live, learn, work and play in communities
that have effective policies and regulations that reduce youth and
adult use and access to tobacco
4. Tobacco prevalence and initiation among young adults, especially
straight-to-work, decreases by 50 percent
5. Initiation among youth, especially high burden and low SES
populations, decreases by 50 percent
6. Exposure to secondhand smoke with an emphasis on low SES
populations decreases by 50 percent
7. Colorado is among the 10 states with the highest price for tobacco
products
15. Tobacco Program Initiatives
• Amendment 35
• State Policy
– Youth Access/Point-of-sale
– Monitor and Sustain CCIAA
– Health Systems
• Federal Partnerships
– CDC
– FDA/Synar
– Healthy Housing
– Medicaid
• Data/Surveillance
• Partnerships/Communication
16. Priority Populations
• Low SES
• Disparately Affected Populations
• Young Adult non-Students
• Youth
17. PSD Work Plan
• Prevent initiation among youth and young
adults
• Promote quitting among adults and youth
• Eliminate exposure to secondhand smoke
• Identify and reduce tobacco-related
disparities among population groups
• Create strategic alignment among A35 review
committees
18. Progress…
Department leadership talking about licensing and tax
BOH resolution around dissolvables
4 communities with licensing/youth access policies
Over 7,000 inspections for compliance with FDA laws (since 2010)
Over 600 youth participating in NOT (FY)
Enhancement of interagency tobacco team
Over 17,000 calls to the Colorado QuitLine (FY)
Facebook and Twitter pages for QuitLine
2 new local policies to enhance CCIAA
3 new local policies to reduce SHS exposure in multi unit housing
Healthy Housing Coalition formed
New strategic plan for tobacco
Full funding return to A35
RFA released, new funding framework
…. and much much more on the horizon
Editor's Notes
Items for the Notes section:Past 20 year prevalence trend – peaked over 24% in 1994 currently at 16% an all time low in Colorado.1.5 billion fewer cigarettes smoked per year in the past decadeProgress has been made, but more to be done.Nationally and in Colo data show that there is a stall in the decrease for both youth and adults
*(2nd Row)$579 per Colorado Household Smoking harms others and costs everyone money. Tobacco addiction results in chronic disease that is expensive to treat and contributes to the ever-increasing medical costs that healthcare reform can’t fully solve. And exposure to second-hand smoke kills others. In fact, it has been shown to contribute to infant SIDS deaths.There are a number of things we are doing at CDPHE to address tobacco use. The one that citizens are most familiar with is Amendment 35.$193 billion – MMWR (2008) 57(45);1226-1228.$2306 million – CDC (2007) Best Practices…Medicare and Medicaid fed stat: Campaign for Tobacco Free KidsState Medicaid _ 2007 CDC Best Practices2nd-hand smoke stat: 2006 Surgeon General’s report on 2nd hand smoke – pg. 5-6.
Adult prevalence has declinedCan see disparities among certain groups ethnicity, age and education (why?)Smoking rate is inversely proportional to educational atainment
Looking more closely at 18-24, highlighting the education disparity.
As you can see from this figure, the rate of ever smoking among both middle and high school students has decreased since 2001. The prevalence of high school ever smokers is twice that of middle school students. While we don’t have income data on youth smoking (don’t ask for it), we know based on other research that kids who smoke are more likely to be low-income, based in part on what we infer from other data about low-income smokers.We know that kids who have friends or family who smoke, who don’t have a trusted adult tell them not to use tobacco, and that are exposed to higher levels of advertising, which is more prominent in low-income neighborhoods, are more likely to try tobacco.
And – a key reason we are all here today – according to the Healthy Kids Colorado survey, 60% of the smokers under 18 who tried to buy tobacco illegally, tell us that the were successful in their attempt. 60 percent!Furthermore, the rate of successful attempts INCREASED 24% between 2006 and 2008.In addition, 53% of youth in grades 6 – 12 said it would be “very easy” or “pretty easy” to get cigarettes if they wanted. *We conducted key informant interviews with several parents. It doesn’t have the statistical validity of the youth survey, but gave us some insights on what parents might think. Most of the parents agreed that it is not hard for underage youth to get cigarettes, and most felt that the current laws are not adequately enforced.When we met with the Youth Partnership for Health, a youth advisory board to the Health Dept, and asked for their opinions, they mirrored the parents. Youth and parents overwhelmingly stated that current laws prohibiting sales to kids under 18 are meaningless if they are not effectively enforced. The retailers – to a lesser extent – agreed that enforcing current laws would make them more effective.
This graph represents current smokeless tobacco among males from high school to adulthood. Often the perception of smokeless tobacco is that the prevalence is higher among older male adults; however, as seen in this graphic, the prevalence currently peaks in high school. Moving forward, the high prevalence among high school students could lead to problems as these males age over time. Again, it is important to remember that we simply don’t know if this data will be reflective of youth use of the newer tobacco products like dissolvables.