This document discusses the rational for using theories, frameworks, and models in implementation science. It provides examples of commonly used theories like the Diffusion of Innovation Theory and the Theory of Planned Behavior. Frameworks like PARIHS and CFIR are also explained. The document emphasizes that theories can help guide research, identify important factors, and explain outcomes. Choosing a theory involves considering its origins, concepts, logical structure, generalizability, testability, and usefulness. Theories can inform implementation planning and tailoring of strategies.