The document outlines various data-driven research areas at Rensselaer Polytechnic Institute, focusing on medical applications, predictive modeling, and data integration. It emphasizes the importance of effective data exploration, discovery, and validation, detailing the role of semantics in enhancing data services and interoperability across disciplines. The Rensselaer Idea aims to empower researchers with advanced tools and cognitive computing to improve understanding and modeling of complex systems.