The human digestive system is approximately 30 feet long and converts food into nutrients and energy. It includes the mouth, esophagus, stomach, small and large intestines, liver, gallbladder and pancreas. Food is broken down mechanically and chemically as it passes through these organs, with enzymes and acids breaking it into smaller molecules that can be absorbed. Nutrients then enter the bloodstream to nourish cells while waste is excreted as feces through the anus.
Human have a special digestive system than the other animals. We have to know how our body digest our food after having a meal. So, let's check it out.
Human have a special digestive system than the other animals. We have to know how our body digest our food after having a meal. So, let's check it out.
Solution of the Special Case "CLP" of the Problem of Apollonius via Vector Ro...James Smith
Using ideas developed in detail in http://www.slideshare.net/JamesSmith245/rotations-of-vectors-via-geometric-algebra-explanation-and-usage-in-solving-classic-geometric-construction-problems-version-of-11-february-2016, this document solves one of the special cases of the famous Problem of Apollonius. A new Appendix presents alternative solutions.
See also:
http://www.slideshare.net/JamesSmith245/solution-of-the-ccp-case-of-the-problem-of-apollonius-via-geometric-clifford-algebra
http://www.slideshare.net/JamesSmith245/rotations-of-vectors-via-geometric-algebra-explanation-and-usage-in-solving-classic-geometric-construction-problems-version-of-11-february-2016
http://www.slideshare.net/JamesSmith245/resoluciones-de-problemas-de-construccin-geomtricos-por-medio-de-la-geometra-clsica-y-el-lgebra-geomtrica-vectorial
Rebranding of "Bro-Ties" : How "Guerrilla Marketing" can be a solution Farzana Yasmin
The problems why "Bro-Ties" could not become a successful business and how "Guerrilla Marketing" can solve that. The slide also covers the importance of guerrilla marketing as well.
OB case study ( Politics of Perfomance appraisal )Farzana Yasmin
The slide which is a OB group presentation, is about on the case; "Politics of performance appraisal" in Eckel Industries based on four managers : Tom, Jim, Lynne and Max and what they feel about the evaluation process that goes on in the company, what are the outcomes and how the process can be modified.
Explain how the structure and function are linked together for the f.pdfhainesburchett26321
Explain how the structure and function are linked together for the following organs of the
digestive system:
1) Mouth
2) Oesophagus
3) Stomach
4) Small intestine
5)Large intestine
6)Rectum
7) Anuss
Solution
I.Mouth:
It is the first organ of the digestive system and food is first taken into the body via the mouth. It
consists of tongue, teeth and saliva. These three elements work together to aid the procedure of
swallowing. Teeth are used for the process of mastication to make the food smaller is size which
is softened by the saliva and turned into bolus by the tongue for aiding the process of
swallowing. Saliva is used for softening the food and digesting starch by the salivary amylase.
Swallowing occurs bytwo involuntary actions - the soft palate, the back of the roof of the mouth,
closes off the nasal cavity, and the epiglottis, a flap of cartilage, tilts downwards to seal the
trachea.
II.II. Oesophagus – the food passes through the throat and enters the food pipe or trachea. The
walls of the oesophagus are muscular and elastic and helps propel the food towards the stomach
by rhythmic muscular contractions called peristalsis. Just before the opening to the stomach is an
important ring-shaped muscle called the lower esophageal sphincter (LES). This sphincter opens
to let food pass into the stomach and closes to keep it there. LES prevents regurgitation.
III.Stomach – the food is propelled into the stomach where it stays for upto five hours. The food
along with the gastric juices of the stomach is converted to chyme by the churning action of the
stomach walls. The stomach walls secrete strong acid (HCl) to make the food acidic in order for
the enzyme pepsin to work. Pepsin is important for the breakdown of proteins. Once the contents
of the stomach are properly processed they are released into the upper small intestine through the
pyloric sphincter.
IV.Small intestine – Small intestine is the longest organ of the digestive system and its composed
of three segments called the Duodenum, Jejunum and ileum. The food is released into the
duodenum from the pyloric sphincter where the pancreatic juices are released along with bile
juice from the bile duct. The bile turns the food alkaline so that the pancreatic enzymes can
process the food. These enzymes require a alkaline medium to digest the fats and lipids. Contents
of the small intestine start out semi-solid, and end in a liquid form after passing through the
organ. Water, bile, enzymes, and mucous contribute to the change in consistency. The duodenum
is largely responsible for the continuous breaking-down process, with the jejunum and ileum
mainly responsible for absorption of nutrients into the bloodstream. Once the nutrients have been
absorbed and the leftover-food residue liquid has passed through the small intestine, it then
moves on to the large intestine, or colon. The small intestine has a folded lining to absorb
nutrients; the lining of the large intestine is flatter
V.Large intestine -.
anatomy: Human digestive system and its partsdrparul6375
Your digestive system is a network of organs that help you digest and absorb nutrition from your food. It includes your gastrointestinal (GI) tract and your biliary system. Your GI tract is a series of hollow organs that are all connected to each other, leading from your mouth to your anus. Your biliary system is a network of three organs that deliver bile and enzymes through to your GI tract your bile ducts.
Peritoneum, abdomen, quadrant and regions.
a) Alimentary digestive organs: Oral cavity, pharynx, esophagus,
stomach, location and parts of stomach, parts of small and large
intestine, villi.
b) Accessory digestive organs: Salivary gland, liver, gall bladder,
pancreas.
Cardiovascular System: Mediastinum, divisions of mediastinum,
anatomy of heart, chambers of heart, opening and valves of the heart,
circulatory system
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
2. The Digestive System
The Digestive system is a series of tube-like organs that
converts our meal into body fuel. In a normal adult, the size is
about 30 feet or 9 meters long.
The parts of Digestive System are :
Mouth, Pharynx, Esophagus, Stomach,
Small Intestines, Large Intestine, Rectum,
Anus.
Key organs that has valuable participation in digestion
process includes, Liver, Gall Bladder, and Pancreas.
3. 1. MOUTH
The mouth is the beginning of the
digestive tract. Digestion Start in your
mouth as soon as you take the first bite
of your food. The Process is called
Ingestion
Chewing mechanically break foods
into pieces that helps for easy
digestion. During chewing food is
mixed with saliva. Saliva is excreted
from salivary gland located on the
lower jaw between the tongue and
teeth.
Saliva converts starch in the food into
sugar and also soften the food.
4. Tongue
Is a fleshy muscular organ that is attached to the floor of
buccal cavity. The taste of food is determined by the taste
bud receptors present in the tongue.
It moves the food freely inside the oral cavity.
It pushes the bolus toward the Pharynx and
into the esophagus when swallowing.
5. 2. PHARYNX
Food is pushed to the
pharynx by the tongue. Tongue
blocks the mouth and soft
palate closes off nose.
Larynx or the Adam’s apple rises
so that the flap-like tissue called
epiglottis can close the opening
of the trachea to prevent food
entering to the lungs.
6. 3. ESOPHAGUS
Esophagus is a muscular tube extending from the pharynx to
the stomach. It is about 10 inches long in a normal adult.
The esophagus delivers food to the stomach by the process
of peristalsis it is the series of smooth muscle contraction
Peristalsis propels food and liquid slowly down the
esophagus and the stomach.
The food travels 4-8 second from the mouth to the stomach.
8. STOMACH
The stomach is a J shaped sac-like organ with strong muscular
walls.
In addition to holding the food, it's also a mixer and grinder.
The stomach secretes acid and powerful enzymes that
continue the process of breaking down the food.
The acid also kills bacteria that is present in the food.
When it leaves the stomach, food is the consistency of a liquid
or paste. From there the food moves to the small intestine.
10. SMALL INTESTINE
Small Intestine are made up of duodenum, jejunum, and ileum
It is a long tube loosely coiled that is about 20 inches long.
The small intestine continues the process of breaking down
food by using enzymes released by the pancreas and bile
from the liver. Bile is a compound that aids in the digestion of
fat and eliminates waste products from the blood.
Peristalsis is also at work in this organ.
The duodenum is largely responsible for continuing the process
of breaking down food.
The Jejunum and ileum being mainly responsible for the
absorption of nutrients into the bloodstream
11. Small Intestine
It takes 4 to 8 hrs. to complete its journey in the small Intestine.
3 organs that play pivotal role in helping the stomach and small
Intestine I digesting foods.
Pancreas – secretes enzymes in the small intestines, the
enzymes breakdown protein, carbohydrates and fats from the
food we eat.
Liver – 2 main function is to make and secret bile and to
cleanse and purify blood coming from small intestine
containing nutrients.
Gall Bladder – pear- shapes located under the liver and stores
bile. Bile is made in the liver travels to the gall bladder via
cystic duct.
During meal, the gall bladder contracts sending bile to the
small Intestine. Once the nutrient have been absorbed and
the left over liquid has passed through the small intestine, what
is left is handed by the Large Intestine other known as Colon.
12. 6. LARGE INTESTINE ( COLON )
It is also known as colon.
It is 5 to 6 foot long muscular tube
that connect cecum to the
rectum. Cecum is the first part of
the large intestine while the rectum
is the distal part.
Stool or waste over the digestion
process is passed through the
colon by means of peristalsis first in
the liquid state and then through
solid form. A stool is stored in the
sigmoid colon for about 10-12
hours until mass movement
empties it into the rectum.
13. Large Intestine
The stool is mostly debris and bacteria.
These bacteria serves several important function
such as synthesizing various vitamins, processing
waste product and food particles and protecting
against harmful bacteria.
When the descending colon becomes full of stool
or feces it empties itself in the rectum to begin the
process of elimination.
14. 7. RECTUM
It is an 8 inches chamber
that connect colon to
the anus.
The job of the rectum is
to receive stools from
the colon to be
evacuated.
When gas or stool
comes to the rectum,
sensory receptors will
send message to the
brain, the brain then
decides if the contents
can be release or not. If
the contents cannot be
expelled, the sphincters
contract and the
rectum accommodates,
so that the sensation
temporarily goes away.
15. 8. ANUS
The anus is the opening where the
gastrointestinal tract ends and exits
the body.
It is the last part of the Digestive
system where the stool/ feces exist.
The anus starts at the bottom of the
rectum, the last portion of the colon.
The anarectal line separates the anus
from the rectum.
Circular muscles called the external
sphincter of ani form the wall of the
anus and hold it closed. Glands
release fluid into the anus to keep its
surface moist.
A plate-like band of muscles, called
the levator ani muscles, surround the
anus and form the floor of the pelvis.
A network of veins lines the skin of the
anus.