The Gupta Empire flourished in India from 320 to 550 CE. Key rulers included Chandragupta I, Samudragupta, and Chandragupta II, who expanded the empire and engaged in profitable trade. The empire was characterized by a relatively free society with advances in mathematics, science, arts, and literature. However, the empire declined due to invasions of the Huns, breaking India into separate kingdoms until the arrival of Muslims.