The Effect of OSA Severity and CPAP Adherence on Weight Regain After Bariatric Surgery
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This study examined whether weight regain after bariatric surgery is correlated with the severity of obstructive sleep apnea (OSA) or adherence to continuous positive airway pressure (CPAP) therapy. The study reviewed data from 116 patients who underwent bariatric surgery and had preoperative OSA testing. On average, patients lost over 35 kilograms initially but regained around 8 kilograms. There was no significant difference in weight regain between those who used CPAP and those who did not. Additionally, the severity of preoperative OSA was not correlated with the amount of initial weight loss or subsequent weight regain.
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Telecoaching plus a portion control plate
for weight care management: a
randomized trial
Jill M. Huber1, Joshua S. Shapiro2, Mark L. Wieland1, Ivana T. Croghan1, Kristen S. Vickers Douglas3,
Darrell R. Schroeder4, Julie C. Hathaway5 and Jon O. Ebbert1,6*
Abstract
Background: Obesity is a leading preventable cause of death and disability and is associated with a lower health-
related quality of life. We evaluated the impact of telecoaching conducted by a counselor trained in motivational
interviewing paired with a portion control plate for obese patients in a primary care setting.
Methods: We conducted a randomized, clinical trial among patients in a primary care practice in the midwestern
United States. Patients were randomized to either usual care or an intervention including telecoaching with a
portion control plate. The intervention was provided during a 3-month period with follow-up of all patients
through 6 months after randomization. The primary outcomes were weight, body mass index (BMI),waist
circumference, and waist to hip ratio measured at baseline, 6, 12, 18, and 24 weeks. Secondary outcomes included
measures assessing eating behaviors, self-efficacy, and physical activity at baseline and at 12 and 24 weeks.
Results: A total of 1,101 subjects were pre-screened, and 90 were randomly assigned to telecoaching plus portion
control plate (n = 45) or usual care (n = 45). Using last-value carried forward without adjustment for baseline
demographics, significant reductions in BMI (estimated treatment effect -0.4 kg/m2, P = .038) and waist to hip ratio
(estimated treatment effect -.02, P = .037) at 3 months were observed in the telecoaching plus portion control plate
group compared to usual care. These differences were not statistically significant at 6 months. In females, the
telecoaching plus portion control plate intervention was associated with significant reductions in weight and BMI
at both 3 months (estimated treatment effect -1.6 kg, P = .016 and -0.6 kg/m2, P = .020) and 6 months (estimated
treatment effect -2.3 kg, P = .013 and -0.8 kg/m2, P = .025). In males, the telecoaching plus portion control
intervention was associated with a significant reduction in waist to hip ratio at 3 months (estimated treatment
effect -0.04, P = .017), but failed to show a significant difference in weight and BMI.
Conclusion: Telecoaching with a portion control plate can produce positive change in body habitus among obese
primary care patients; however, changes depend upon sex.
Trial registration: ClinicalTrials.gov NCT02373878, 13 February 2015. https://clinicaltrials.gov/ct2/show/
NCT02373878.
Keywords: Obesity, Telecoaching, Portion control plate, Primary care, Patient-centered medical home
* Correspondence: [email protected]
1Division of Primary Care Internal Medicine, Department of Medicine,
Rochester, MN 55905, USA
6Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA
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Enhanced recovery after surgery (eras)
The ERAS protocol was developed in 2001 to improve surgical recovery through evidence-based practices. It utilizes a multidisciplinary team and multimodal interventions including preoperative education and carbohydrate loading, intraoperative fluid management and opioid-sparing techniques, and postoperative early nutrition, ambulation and defined discharge criteria. Implementation of ERAS has been shown to reduce length of hospital stay by 35-40% and complications rates while lowering healthcare costs. While initially developed for colorectal surgery, ERAS has been applied to other specialties and demonstrated benefits but faces barriers to widespread adoption including resistance to changing traditional practices.
Sindrome obesidade hipoventilação tratamento cónico
This document summarizes research on obesity hypoventilation syndrome (OHS). It finds that compared to other obese patient groups, patients with OHS have higher healthcare costs and risks of serious cardiovascular disease leading to early mortality. However, diagnosis and treatment of OHS is often late. Non-invasive ventilation can improve symptoms and gas exchange in OHS, but more research is needed comparing non-invasive ventilation to other treatments like CPAP. Weight loss through bariatric surgery may reverse the effects of OHS, but long-term data is limited. Overall, the document examines the morbidity, mortality and treatment options for OHS.
Research Poster
This document summarizes and compares two studies on bariatric surgery procedures - Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding. The first study found that gastric banding revision surgery is generally well-tolerated by patients and maintains existing weight loss. The second study found that maintaining a patient database to aid in long-term follow-up after Roux-en-Y gastric bypass surgery helps monitor patients and allows for more aggressive control following surgery, while inability to maintain follow-up is a significant problem. The document recommends nurses incorporate evidence-based research on these procedures to better educate patients and standardize post-operative follow-up protocols.
Evidence based medicine and cosmetic surgery
This document discusses the relationship between evidence-based medicine and aesthetic plastic surgery. It provides definitions of evidence-based medicine and outlines its five primary components. The document then examines several examples of how evidence-based medicine has been applied to topics in aesthetic plastic surgery, including bariatric surgery outcomes, breast augmentation practices like antibiotic use and drain usage, and outcomes of facelifts with or without drain usage. It acknowledges that while plastic surgery literature often contains lower levels of evidence, the field should aim to both appreciate existing evidence and continue raising the overall level of evidence to best serve patients.
Fast-track surgery - the role of the anaesthesiologist in ERAS
A presentation by Narinder Rawal at the 2017 meeting of the Scandinavian Society of Anaestesiology and Intensive Care Medicine.
All available content from SSAI2017: https://scanfoam.org/ssai2017/
Delivered in collaboration between scanFOAM, SSAI & SFAI.
Fast track surgery eras 2
Fast-track or enhanced recovery after surgery (ERAS) protocols aim to reduce the stress response to surgery and speed recovery. This document outlines ERAS protocols for several types of surgeries including colorectal, bariatric, liver, breast and gallbladder surgeries. The protocols emphasize preoperative counseling and nutrition, minimal invasive surgery when possible, multimodal pain control, early feeding and mobilization to reduce hospital length of stay and complications compared to traditional care.
Nejm journal watch practice changing articles 2014
This document provides a compilation of summaries of the latest practice-changing articles from NEJM Journal Watch. It includes summaries of articles on topics such as delayed or no antibiotic prescriptions for respiratory infections, physical therapy being beneficial for knee osteoarthritis, low-dose steroids being better than high-dose for COPD exacerbations, a diagnostic algorithm for upper-extremity deep vein thrombosis, evidence that meniscal tears may not require surgery, improvements in mental health with smoking cessation, doubts cast on flu drugs by meta-analyses, the 2014 recommended childhood immunization schedule, sentinel lymph node biopsies for thin melanomas, age-specific d-dimer cutoffs for pulmonary embolism, evidence that FOD
ibuprofen therapy journal.pptx
This study evaluated the efficacy of a single prophylactic dose of intravenous ibuprofen on the first day of life in closing a patent ductus arteriosus in preterm infants. The study found that a single ibuprofen dose resulted in a higher rate of ductal closure at 24 hours and through the first week compared to infants who did not receive prophylactic treatment. Additionally, infants receiving a single dose had a shorter duration of ventilation and hospitalization with no increase in adverse outcomes. The study concludes that a single ibuprofen dose may effectively close a PDA while avoiding risks associated with multiple dose therapy.
RECENT ADVANCES IN EXERCISE INTERVENTION FOR FATIGUE MANAGEMENT IN PATIENTS W...
This document summarizes recent advances in exercise interventions for managing fatigue in patients with gynecologic cancer. It reviews 3 studies that investigated the effects of different types of exercise on fatigue. A randomized controlled trial found that a 12-week resistance exercise program significantly improved quality of life and reduced fatigue in patients with gynecologic cancer compared to a control group. Another study found that relaxation breathing exercises conducted 4 times daily for 30 minutes significantly reduced fatigue in women receiving chemotherapy, more so than exercises conducted 2 times daily. A systematic review concluded that resistance, aerobic, flexibility, and breathing exercises can all help alleviate fatigue in this patient population, but noted limited evidence and called for additional research.
Clinical prediction rule in spinal pain
This lecture is on spinal pain and the clinical methods used in treating the pain. Clinical prediction rules is a research method done systematically describing when to use which method of treatment approach
Similar to The Effect of OSA Severity and CPAP Adherence on Weight Regain After Bariatric Surgery (20)
Using Enhanced Recovery After Surgery (ERAS) to Enhance Postoperative Outcomes
Using Enhanced Recovery After Surgery (ERAS) to Enhance Postoperative Outcomes
UOG Journal Club: Prevention of postpartum hemorrhage and hysterectomy in pat...
UOG Journal Club: Prevention of postpartum hemorrhage and hysterectomy in pat...
Intra Abdominal Hypertension and Abdominal Compartment Syndrome in Children
Intra Abdominal Hypertension and Abdominal Compartment Syndrome in Children
Next day discharge following elective caesarean section
Next day discharge following elective caesarean section
Analysis of Spinal Decompression via Surgical Methods and Traction Therapy
Analysis of Spinal Decompression via Surgical Methods and Traction Therapy
RESEARCH Open AccessTelecoaching plus a portion control pl.docx
RESEARCH Open AccessTelecoaching plus a portion control pl.docx
Sindrome obesidade hipoventilação tratamento cónico
Sindrome obesidade hipoventilação tratamento cónico
Fast-track surgery - the role of the anaesthesiologist in ERAS
Fast-track surgery - the role of the anaesthesiologist in ERAS
Nejm journal watch practice changing articles 2014
Nejm journal watch practice changing articles 2014
RECENT ADVANCES IN EXERCISE INTERVENTION FOR FATIGUE MANAGEMENT IN PATIENTS W...
RECENT ADVANCES IN EXERCISE INTERVENTION FOR FATIGUE MANAGEMENT IN PATIENTS W...
More from Brian Locke
End of Response issues - Code and Rapid Response Workshop
https://reblocke.github.io/talks/2024-Code-RR
Personnel and Equipment - Code and Rapid Response Workshop
https://reblocke.github.io/talks/2024-Code-RR
Locke arrhythmia
This document provides an overview of arrhythmias for medical residents. It outlines an approach to classifying arrhythmias based on rate, regularity, and QRS width. Specific arrhythmias covered include sinus bradycardia, atrial fibrillation, atrial flutter, AV nodal reentrant tachycardia, ventricular tachycardia, and various types of heart block. The document also discusses how to determine if a wide complex tachycardia requires cardioversion or defibrillation versus medical treatment. Examples of EKGs are provided for different arrhythmias.
Locke intro ekg
This document provides an introduction to EKG interpretation and outlines the systematic approach of evaluating an EKG. It covers the key components to assess, including rate, rhythm, axis, conduction abnormalities, and morphology. Specific conditions are reviewed such as sinus rhythm, bundle branch blocks, AV blocks, ischemia, and infarction. Examples are provided throughout to demonstrate application of the principles. The overall goal is to understand the fundamentals of the EKG and systematically analyze it following the standard approach of rate, rhythm, axis, conduction, morphology.
Locke chf greatest hits
This document provides an overview of congestive heart failure, including definitions, types, classification, time course, and treatment strategies. It defines CHF as a syndrome most commonly caused by cardiomyopathy. It describes types as right or left heart failure, and with reduced or preserved ejection fraction. Treatment objectives for acute CHF are to decrease congestion and increase perfusion, while chronic CHF aims to slow functional decline. Key medications that improve mortality in chronic CHF include ACE inhibitors, beta blockers, aldosterone antagonists, and ARNI.
Locke test chars
This document discusses key concepts for understanding medical tests, including sensitivity, specificity, predictive values, and how to construct a contingency table. It begins by defining sensitivity as the percentage of true positives among those with the disease, and specificity as the percentage of true negatives among those without the disease. Prevalence affects the numbers in the contingency table. Positive and negative predictive values depend on prevalence in addition to sensitivity and specificity. Examples are used to illustrate these concepts for different diseases and testing scenarios.
Ebm seminar b locke 5-16-20
This document provides an overview of an evidence-based medicine seminar. It discusses using medical literature to help make better clinical decisions. The learning objectives are to understand EBM, ask clinical questions, understand different types of medical literature and validity, apply Bayes' theorem to diagnosis, understand metrics for treatment effects, and access secondary sources. It emphasizes using a structured approach to ask, acquire, assess, and apply evidence to answer clinical questions.
Resident research pp final
This document provides guidance to residents on productive scholarly work and mentorship. It outlines the scholarly activity requirement, importance of mentorship, timeline for research projects, and types of projects residents should consider. These include case reports, quality improvement projects, retrospective research, reviews, editorials, and education/teaching projects. Choosing a project aligned with career goals and that has support from a mentor will maximize the chances of a successful scholarly experience.
Locke vasopressor ppt
This document discusses the fundamentals of using vasopressors. It outlines the steps to determine when to start vasopressors: 1) Is the patient's blood pressure too low? 2) Why is the blood pressure low? 3) How to raise the blood pressure? Norepinephrine is generally the first-line vasopressor. Adjuncts like vasopressin and steroids may be considered if norepinephrine dose is high. Peripheral intravenous lines can be used for vasopressors in the short term but central lines are preferable at higher doses due to risk of extravasation from peripheral lines.
Virtual noon conf template
This document outlines the structure and approach for presenting and discussing a patient case, including defining the problem representation, generating a differential diagnosis, presenting pertinent history, exam findings, labs/imaging, investigations, diagnosis, and management. Key aspects include updating the problem representation and differential with each new piece of information, and separating the diagnostic "signal" from irrelevant "noise".
Tti top 10 on call anton locke 4-11-20
The document provides guidance for medical residents on handling on-call duties, including tips for sign-out, answering calls, and protocols for managing the five most common and five scariest call scenarios. It outlines approaches for prioritizing tasks, responding to and triaging calls, and standardized processes for issues like insomnia, nausea, pain, constipation, high blood pressure, NPO restrictions, patients leaving AMA, abnormal heart rhythms, and managing insulin. The goal is to equip residents with effective strategies and decision-making frameworks for their on-call responsibilities.
Locke covid transmission 101
This document discusses SARS-CoV-2 transmission and characteristics. It addresses how the virus can spread through small aerosols or large droplets, and the protective measures appropriate for each. It also examines the virus's ability to spread before symptoms appear and challenges for contact tracing. Additionally, it covers the reproductive number of the virus and importance of identifying mild and asymptomatic cases.
Scarce resources
This document discusses challenges related to rationing care and crisis standards during the COVID-19 pandemic. It presents two cases where a hospital is at capacity and needs to decide whether to remove a patient from a ventilator or withhold intubation to reallocate the ventilator to other patients with better prognoses. It also discusses the ethics of prioritizing the needs of individual patients versus the wider population and proposes establishing crisis triage teams to make difficult resource allocation decisions impartially. The document further examines precedents for rationing healthcare resources like dialysis and transplants as well as who should receive priority for scarce COVID vaccines. It also outlines Utah's crisis standards of care plan implemented by the governor during public health emergencies
Covid diagnostics users guide
This document provides a guide to COVID-19 testing. It discusses PCR testing and its sensitivity of over 85%. Sensitivity measures how often a test correctly identifies those with the disease, while positive predictive value depends on disease prevalence. Likelihood ratios are used to determine pre-test and post-test probability. Examples are given of using test results and likelihood ratios to determine the probability a patient has COVID-19. CT scans are not recommended for diagnosing COVID-19 due to their low sensitivity. Symptoms and risk factors should be used to determine pre-test probability to correlate with test results.
Covid imaging users guide
The document provides guidance on using imaging for COVID-19, including when it is useful, what findings to look for on chest x-ray and CT scan, and why clinical history is important. It discusses that imaging is not recommended for screening but can help evaluate symptoms. Chest x-ray may show patchy, peripheral, bilateral opacities while CT scan commonly shows peripheral ground glass opacities. Radiologists need full clinical history to properly interpret imaging studies.
Pancpleural fistula am report locke
This document discusses the analysis and management of pleural fluid and pancreaticopleural fistulas. It outlines criteria for distinguishing transudative, exudative, and lymphatic pleural effusions. It notes that amylase-rich pleural fluid could indicate a pancreatic or cancerous origin, and diagnostic testing of pleural fluid has about a 50% yield for detecting cancer. Management options for pancreaticopleural fistulas include observation for spontaneous resolution in 40-60% of cases within 6 weeks, octreotide to lower output, enteral feeding, and stent placement which can resolve the fistula in 55-90% of cases.
Pneumocystis PNa and HyperCa
A 74-year-old woman on immunosuppressive medications for oral lichen planus presented with worsening respiratory failure after being treated for hypercalcemia. Initial tests showed increased oxygen needs and abnormal chest x-ray. She was diagnosed with Pneumocystis jirovecii pneumonia (PJP) based on a positive PCR test of her lungs. PJP is a fungal infection that causes pneumonia in immunocompromised patients. While her symptoms began with hypercalcemia, it is possible the underlying cause was an atypical infection like PJP leading to abnormal vitamin D activation. She was treated successfully for PJP with antibiotics and steroids.
More from Brian Locke (20)
End of Response issues - Code and Rapid Response Workshop
End of Response issues - Code and Rapid Response Workshop
Personnel and Equipment - Code and Rapid Response Workshop
Personnel and Equipment - Code and Rapid Response Workshop
Leadership Style - Code and Rapid Response Workshop
Leadership Style - Code and Rapid Response Workshop
Pulse Check Decisions - RRT and Code Blue Workshop
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Phenomics assisted breeding in crop improvement
As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
Randomised Optimisation Algorithms in DAPHNE
Slides from talk:
Aleš Zamuda: Randomised Optimisation Algorithms in DAPHNE .
Austrian-Slovenian HPC Meeting 2024 – ASHPC24, Seeblickhotel Grundlsee in Austria, 10–13 June 2024
https://ashpc.eu/
Thornton ESPP slides UK WW Network 4_6_24.pdf
ESPP presentation to EU Waste Water Network, 4th June 2024 “EU policies driving nutrient removal and recycling
and the revised UWWTD (Urban Waste Water Treatment Directive)”
20240520 Planning a Circuit Simulator in JavaScript.pptx
Evaporation step counter work. I have done a physical experiment.
(Work in progress.)
Nucleophilic Addition of carbonyl compounds.pptx
Nucleophilic addition is the most important reaction of carbonyls. Not just aldehydes and ketones, but also carboxylic acid derivatives in general.
Carbonyls undergo addition reactions with a large range of nucleophiles.
Comparing the relative basicity of the nucleophile and the product is extremely helpful in determining how reversible the addition reaction is. Reactions with Grignards and hydrides are irreversible. Reactions with weak bases like halides and carboxylates generally don’t happen.
Electronic effects (inductive effects, electron donation) have a large impact on reactivity.
Large groups adjacent to the carbonyl will slow the rate of reaction.
Neutral nucleophiles can also add to carbonyls, although their additions are generally slower and more reversible. Acid catalysis is sometimes employed to increase the rate of addition.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...
The pygmy halfbeak Dermogenys colletei, is known for its viviparous nature, this presents an intriguing case of relatively low fecundity, raising questions about potential compensatory reproductive strategies employed by this species. Our study delves into the examination of fecundity and the Gonadosomatic Index (GSI) in the Pygmy Halfbeak, D. colletei (Meisner, 2001), an intriguing viviparous fish indigenous to Sarawak, Borneo. We hypothesize that the Pygmy halfbeak, D. colletei, may exhibit unique reproductive adaptations to offset its low fecundity, thus enhancing its survival and fitness. To address this, we conducted a comprehensive study utilizing 28 mature female specimens of D. colletei, carefully measuring fecundity and GSI to shed light on the reproductive adaptations of this species. Our findings reveal that D. colletei indeed exhibits low fecundity, with a mean of 16.76 ± 2.01, and a mean GSI of 12.83 ± 1.27, providing crucial insights into the reproductive mechanisms at play in this species. These results underscore the existence of unique reproductive strategies in D. colletei, enabling its adaptation and persistence in Borneo's diverse aquatic ecosystems, and call for further ecological research to elucidate these mechanisms. This study lends to a better understanding of viviparous fish in Borneo and contributes to the broader field of aquatic ecology, enhancing our knowledge of species adaptations to unique ecological challenges.
BREEDING METHODS FOR DISEASE RESISTANCE.pptx
Plant breeding for disease resistance is a strategy to reduce crop losses caused by disease. Plants have an innate immune system that allows them to recognize pathogens and provide resistance. However, breeding for long-lasting resistance often involves combining multiple resistance genes
SAR of Medicinal Chemistry 1st by dk.pdf
In this presentation include the prototype drug SAR on thus or with their examples .
Syllabus of Second Year B. Pharmacy
2019 PATTERN.
bordetella pertussis.................................ppt
Bordettela is a gram negative cocobacilli spread by air born drop let
Equivariant neural networks and representation theory
Or: Beyond linear.
Abstract: Equivariant neural networks are neural networks that incorporate symmetries. The nonlinear activation functions in these networks result in interesting nonlinear equivariant maps between simple representations, and motivate the key player of this talk: piecewise linear representation theory.
Disclaimer: No one is perfect, so please mind that there might be mistakes and typos.
dtubbenhauer@gmail.com
Corrected slides: dtubbenhauer.com/talks.html
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Applied Science: Thermodynamics, Laws & Methodology.pdf
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
Nucleic Acid-its structural and functional complexity.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
The binding of cosmological structures by massless topological defects
Assuming spherical symmetry and weak field, it is shown that if one solves the Poisson equation or the Einstein field
equations sourced by a topological defect, i.e. a singularity of a very specific form, the result is a localized gravitational
field capable of driving flat rotation (i.e. Keplerian circular orbits at a constant speed for all radii) of test masses on a thin
spherical shell without any underlying mass. Moreover, a large-scale structure which exploits this solution by assembling
concentrically a number of such topological defects can establish a flat stellar or galactic rotation curve, and can also deflect
light in the same manner as an equipotential (isothermal) sphere. Thus, the need for dark matter or modified gravity theory is
mitigated, at least in part.
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mô tả các thí nghiệm về đánh giá tác động dòng khí hóa sau đốt
mô tả các thí nghiệm về đánh giá tác động dòng khí hóa sau đốt
20240520 Planning a Circuit Simulator in JavaScript.pptx
20240520 Planning a Circuit Simulator in JavaScript.pptx
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...
Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...
bordetella pertussis.................................ppt
bordetella pertussis.................................ppt
Equivariant neural networks and representation theory
Equivariant neural networks and representation theory
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...
Applied Science: Thermodynamics, Laws & Methodology.pdf
Applied Science: Thermodynamics, Laws & Methodology.pdf
Nucleic Acid-its structural and functional complexity.
Nucleic Acid-its structural and functional complexity.
The binding of cosmological structures by massless topological defects
The binding of cosmological structures by massless topological defects
The Effect of OSA Severity and CPAP Adherence on Weight Regain After Bariatric Surgery
- 1. Non-Cognitive Predictors of Student Success: A Predictive Validity Comparison Between Domestic and International Students Weight regain after bariatric surgery was not correlated with OSA severity or CPAP Adherence BACKGROUND 1 in 5 patients undergoing bariatric surgery regain significant weight after their initial weight loss. Many of these patients have obstructive sleep apnea (OSA), which is known to cause worsening adrenergic tone, inflammation, and insulin resistance. METHODS 1. All patients undergoing bariatric surgery at University of Utah (Apr 2011 to Jan 2016) required preoperative sleep disordered breathing evaluation. 2. Retrospective chart review of weight and CPAP-machine adherence tracking 3. All adult patients undergoing bariatric surgery and had OSA testing or treatment at U of U were included 4. Unadjusted comparison of patients who had any CPAP adherence to those with none 5. Unadjusted linear regression of diagnostic AHI and maximum weight loss and regain PATIENTS • N=116 patients met inclusion criteria • Preoperative BMI 45.7 ± 8.2 • Preoperative AHI 34.9 ± 31.7 /hour. • 81 of 116 had any post-op CPAP usage • Of patients with usage , average adherence in available downloads was 66.8 ±% days with 4 or more hours of use. OUTCOMES • Weights were available up to 36.1 ± 16.5 months after surgery • Weight nadir occurred 16.8 ± 12.7 months • N=35 patients with no usage lost 37.8 ± 20.2 kg, followed by 6.1 ± 7.7 kg regain • N=81 patients with CPAP usage lost 35.97 ± 16.3 kg followed by 8.2 ± 9.0 kg regain. (p=0.19 for difference, Main Figure) • No relation between diagnostic AHI and initial weight loss or weight regain (below) STRENGTHS/LIMITATIONS • High adherence among CPAP users • Differential follow-up between groups, healthy adherer bias Take a picture to download the abstract PRESENTER: Brian W Locke, MD Weight Regain After Bariatric Surgery Impact of OSA Severity and CPAP Adherence Brian W Locke, MD Jaewhan Kim, PhD Jeffrey Bennion Colline Prasad, RN Eric Volckmann, MD Krishna Sundar, MD