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!
!
EXPONENTIAL DISRUPTION
!
!
SALIM ISMAIL
@salimismail
// Global Ambassador, Founding Executive Director
Singularity University

// Co-Founder
Angstro
Confabb
PubSub
!
// Vice President
Yahoo
Digitize
Disrupt
Demonetize
Democratize
Information Layers
New 
Breakthroughs
Singularity University was founded in Sept 2008
by Drs. Ray Kurzweil & Peter Diamandis
Accelerating
Technologies
Al
Robotics
Biotech
Nanotech
Medicine
Neuroscience
Energy
Computing
www.singularityu.org
Other Notable:
•Sebastian Thrun, Stanford AI, GoogleX; Founder – Udacity
•Saul Griffith, PhD, Eyeglasses, Squid Labs, Instructables.com,
Makani Power
•Dan Kammen, PhD – Lead Author, 2007 Nobel Peace Prize-winning
IPCC report; Faculty, UC Berkeley
•Bob Metcalfe, PhD, Founder, 3Com; co-inventor of Ethernet
•Chris DiBona, Open Source Program Manager, Google Inc.
•Larry Smarr, PhD, California Inst. for Telecom & IT
•Chris deCharms, PhD, Founder Omneruon
•Tim Ferriss, Author- 4-hour Workweek
Sonia Arrison
Senior Fellow, Pacific Research
Institute
Aubrey de Grey, PhD
Chairman & CSO, SENS
Foundation
Vint Cerf
Chief Internet Evangelist,
Google
Will Wright
Creator – SimCity, Spore;
Founder, Maxis (EA)
George Smoot, PhD
UC Berkeley; 2006 Nobel Prize
in Physics
Tina Seelig
Exec Dir Stanford Tech
Ventures
Justin Rattner
CTO, Intel Labs
Yvonne Cagel, M.D.
Astronaut, Colonel- USAF
Dean Kamen
Inventor,
Founder DEKA
Craig Venter
Founder, CEO Synthetic Genomics
EXAMPLES OF ADVISORY FACULTY & SPEAKERS

“You’re not really a university, and you’re not really
about the Singularity, so what are you?”
!
Garrett Lisi, Quantum Physicist
Innovation Engine
10 Week Program phases:
SU EPO11 Participant Feedback
1.4 billion in extreme poverty
1 billion with no access to all-season roads
Grand Challenge
1 billion with no access to all-season roads
It will take Africa 50 years to catch up
Executive program overview
Executive Program
Participants: 
!
Entrepreneurs, CEOs, CTOs,
investors, inventors, government
leaders, and policy experts from
around the world
www.singularityu.org
CURRENT PROGRAMS AND VISION
1.	
  Educa)on	
  Forums 2.	
  	
  Online	
  Pla6orm
3.	
  Singularity	
  Labs
4.	
  Interna)onal
Graduate Studies Program
10 Weeks
Executive Programs
7 Days
FutureMed
5 Days
Custom
1 -3 Days
Future X
3-5 Days
Innova&on	
  Hubs
Global	
  Impact	
  Compe&&ons
Global	
  Community
Incubator	
  &	
  Entrepreneurship
Innova&on	
  Hubs
SU	
  Ventures
Singularity	
  Hub
Online	
  Educa&on
Community	
  Tools
- -
Before: 75% had little or zero
awareness of breakthroughs
Current IPP Partners
- -
After:
!
Game-changing
impact (80% in 2
yrs, 100% in 5 yrs)
!
100% said they
had immediate
action items
Differentiation
Disruptive
Stress/
Opportunity
Exponential
Thinking 109+Grand
Challenges
Incredible
People
Curriculum Planning Meetings
Digitize
Disrupt
Demonetize
Democratize
Information Layers
New 
Breakthroughs
Rate of Change Increasing
Exponential computing
1900 1925 1950 1975 ‘01 ’10 ’23 2050 2075
...one insect brain
...one mous brain
...one human brain
...all human brains
10
1
10
10
10
10
-10
10
20
30
40
Plotted by number of calculations per sec
per $1,000
HOLLERITH TABULATOR
UNIVAC 1
APPLE
MAC II
= COMPUTER TYPE
E X P O N E N T I A L L Y 
!
S M A L L E R 
C H E A P E R 
B E T T E R
F A S T E R
Internet of Things 
50B devices by 2020
Google Confidential and Proprietary
M2M communication will be 
> 50% 
of data traffic by 2030
1 trillion 
connected devices 
using low bandwidth
Oculus Rift
Google Glass
Decoding the human intonation * * It’s all in our head, really
18 years of research
Over 60,000 subjects world-wide
4 active researches
4 approved US patents 

(and two more on the way…)
Major awards
Dr. Yoram Levanon
Decision Making, Physics
Dr. Lan Lossos
Neuropsychology
Father teaches daughter a lesson
Moodies
Digitize
Disrupt
Demonetize
Democratize
Information Layers
New 
Breakthroughs
Why information » exponential
// zero friction to move/copy
// zero marginal cost
// apply computation
// data correlations
// machine learning
// modeling
// simulations
!
// 100% democratization
of effort/innovation
Why information » exponential
3D printing / Digital fabrication
3d printed car
Michael Curry
3D printing - makeup
3d printed car
Michael Curry
AI & Robotics
Dan Barry, MD
!
(Space, AI, Robotics)
NASA Astronaut
Neil Jacobstein
!
(AI, Robotics)
AI CEO, Visiting
Scholar
Stanford
Last upgrade - 50k years
Ancient architecture
Torrents of data
Hardwired biases
Limited bandwidth
Technological amplification
Change accelerating
Global problems
Navigation requirements increasing
Anchoring bias – fixating on 1st impressions
Status quo bias – failure to consider alternatives to what is
Sunk-cost bias – protecting earlier bad choices
Confirming-evidence bias – selective data collection
Framing bias – posing the wrong question
Overconfidence bias – failure to challenge assumptions 
Saliency bias – focus on dramatic events vs whole picture
Base-rate bias – neglecting relevant baseline information
Pattern invention bias – imposing patterns on events
Prudence bias – slanting probabilities & estimates
Biases & heuristics in human cognition
Shai Danziger - 1,112 parole hearings
IBM Watson
Other applications:
!
Healthcare
Education
Travel
E M B E D D E D A I : 
S E N S E , P L A N , A C T
www.singularityu.org
ExpectationReality
POPULAR ROBOTS
www.singularityu.org
Remote-control
Fully Autonomous
Narrow
Purpose
General
Purpose
Replacement	

Enhancement	

Health & Therapy	

Research/Education	

Transformative
AUTONOMY & PURPOSE
www.singularityu.org
Atlas
32 1:16http://www.youtube.com/watch?v=Dl40uEjcP3o
PetMan
Boston Dynamics
Replacement/
Assistance
http://www.youtube.com/watch?v=SD6Okylclb8
Was $ 700
Today $ 20
www.singularityu.org
GOOGLEX ROBOT FUTURE?
Andy Rubin, GoogleX
www.singularityu.org
PR2 - Willow Garage
Roomba - IRobot
ASSISTANCE AT HOME
Replacement/
Assistance
UBR1 - Unbounded Robotics
www.singularityu.org
ROBOTIC TELEPRESENCEEnhancement
www.singularityu.org
Baxter - ReThink Robotics	

$22,000
NEW WAVE OF MFG ROBOTS - BAXTER
Replacement/
Assistance
Baxter: 22,000 $
Pneumatic
Robotics
www.singularityu.org
Safer (No human exposure)	

Cheaper (Labor costs, scale)	

Faster (Speed,Acceleration)	

Better (Accuracy, Precision, Processing Intelligence)	

Exponentially:	

RISE OF THE ROBOTS
Education/
Entertainment
Replacement/
Assistance
Health & Therapy
Enhancement
Transformative
Big Implication:
JOBS
Industrial
Robotics
Defense/ Military
www.singularityu.org
UNIVERSITY OF WASHINGTON	

-
Rajesh Rao and Andrea Stocco August 28, 2013
Education/
Entertainment
www.singularityu.org
On the horizon - Real Emotions & the “Uncanny Valley”
Hanson Robotics
MIT - MDS Robot
www.singularityu.org
IPhone control
Automated software processes
control wing flap frequency,
amplitude, and angle
“A model that can master more flight conditions than a
helicopter, plane, and glider combined.”
BionicOpter April 2, 2013
Education/
Entertainment
www.singularityu.org
Still on the horizon - General Object Recognition
www.singularityu.org
•Augmented Reality	

•Decision Support	

•Remote Mentoring	

•Scarless surgery	

•Training
DaVinci - Intuitive Surgical
ROBOTIC SURGERY
Replacement/
Assistance
Enhancement Health & Therapy
Google Car - www.robocars.com
Brad Templeton
(Computer & Networks)
Chairman EFF
Lidar • 64 lines, 50m pavement, 120m cars
• 1.3m points/.sec
• 1cm accurate
• $75K today, $300 later
Paradigm Change: Robotic Vehicles
6 Prius
3 RX450h
!
>600,000 miles
!
Legal in:
- Nevada
-California
-Florida
photo: Paul Saffo
Biotech & Bioinformatics
Raymond McCauley
!
(Biotechnology)
CSO-Genomera; 
Founder - BioCurious
Moore’s Law
Biotech
87
Arctic
Apple
www.singularityu.org
GROWING MEAT
!
Making Leather and Meat Better
!
Modern Meadow applies the latest advances in tissue engineering to develop
novel biomaterials to address some of our most pressing global challenges. We
develop cultured leather and meat products which require no animal slaughter
and much lower inputs of land, water, energy and chemicals.
// Ancient architecture
// Torrents of data
// Hardwired biases
// Limited bandwidth
// Technological amplification
// Change accelerating
// Global problems
// Navigation requirements increasing
Neuroscience
Neuroscience
Sherbondy, Ananthanrayanan, Dougherty, Wandell, and Modha, HBM, 2009
// BCI & FMRI
// Optical technologies
// Cloud computing
// Sensors & IoT
// Artificial Intelligence
// Storage & big data
// Feedback loops
// Gaming/social dynamics
… nanowires!
Confluence of acceleration
Old EEG Muse EEG
NeuroSky
Mindwave
Axio Headband NeuroVigil
iBrain
Brain Computing Interfaces (BCI)
Storing dreams
// Dreamcatcher
!
// MRI machine
!
// Stores images
!
// Replays your dreams
Diffuse Optical Tomography (DOT)
Nature Oct/10
Optogenetics
Pioneered by Karl Diesseroth
& others
!
Intersection of genetics,
virology and optics
!
Saling quickly
!
Implications: priceless
www.singularityu.org
HARVARD UNIVERSITY	

 - BRAIN TO BRAIN
INTERFACE CONTROL - April 8, 2013
Education/
Entertainment
http://www.youtube.com/watch?v=pL0FzHHrQv8
SOURCE: SAU
Source: Saul Griffith
materials
project
Scanning Tunneling Microscope!
Positional Assembly
Experimental
…successive substitution of Sn atoms at the surface
one atom at a time with Si atoms coming from the
tip. !
Science 17 October 2008: vol. 322. no. 5900, pp. 413
– 417. Custance Nanomechanics Group.!
Tin & Silicon
The Goal
// Arrange any element
// Inexpensively
//Fewer elements: H and C can build
almost any rigid structure (diamond,
lonsdaleite, graphite and graphene,
carbon nanotubes and fullerenes,
polyynes, other hydrocarbons)
// Ge provides “just enough” synthetic
flexibility
!
Molecular Manufacturing
Accelerating
Technologies
Al
Robotics
Biotech
Nanotech
Medicine
Neuroscience
Energy
Computing
“The complexity of modern American medicine exceeds the
capacity of the unaided human mind.” David Eddy, MD
TMI: Too much information
Daniel Kraft, MD
(Medicine)
Stem cell Biology,
Stanford
Records Exams Labs Vaccines Rx Drugs History Environment Vitals
VIRTUAL COLONOSCOPY
Virtual colonoscopy Traditional
Medicine Track Daniel Kraft MD
vs
Intelligent
Integration	

!
Making it 	

ACTIONABLE
Scanadu
Courtesy: Shutterstock
121
Solar
Digitize
Disrupt
Demonetize
Democratize
New 
Breakthroughs
Information Layers
Recent News
LIFE
Local & linear
LIFE
Exponential & global
Society is not ready..
Google Confidential and Proprietary
Social media is a menace to society
Erdogan
Turkey Prime Minister - National Post
Google Confidential and Proprietary
Regulatory
Frameworks
// Privacy (cloud)
// Identity
// Anonymity
// Surveillance
- Retrospective
- Prospective
Curriculum Planning Meetings
Discussion / Q&A
Digitize
Disrupt
Demonetize
Democratize
New 
Breakthroughs
Information Layers
B I L L I O N $ C O M P A N I E S
N
T
!
A billion dollar opportunity
!
Used to take 20 years to create
Google - 8 years
Facebook - 5 years
Groupon - 18 months
!
!
Metabolism of the economy
increasing
!
Barriers to entry dropping
$ 8 0 0 M S A L E S I N 2 4 H R S 
> $ 1 B I N 7 2 H R S
N E W I N F O R M A T I O N
L A Y E R S
HTML (text) Video
Social Profiles
Location
Quantified Self
Health Data
Sensor Networks
Internet of Things
Newspapers
Netflix 
4 billion 
hours in Q1 2013
2002
16%
2004
14%
2006
12%
2008 10%
Vinod Khosla // The rise of mobile phones
Chaos/ 
Amazement
You are
here
Disappointment
Deception of linear 
vs exponential
140
Digitize
Disrupt
Demonetize
Democratize
New 
Breakthroughs
Information Layers
Quotient technology platform: 
standing on the shoulders of giants
Historic event in human-antibody therapy:
!
Dr. William Pollack – eminent immunologist,
foremost authority on human antibodies
!
Inventor of RhoGam® – one of the most
successful women’s health products ever produced
!
Tens of millions of babies saved
Eradicated RH disease
!
Further invented first vaccine against Hepatitis B –
human antibody based
Eric Migicovsky - Pebble
Seed round: $100k
!
20 investors
!
Raised: $ 0
33
Crowdfunding – Kickstarter
Brain interface (Neuro)
NeuroSky Mindwave
www.focusatwill.com
152
Bitcoin
The Bitcoin Block Chain
http://bitly.com/bitcoinsalim
Bitcoin Protocol - other uses
International payments
!
Contracts
!
Transaction logs
!
Voting systems
!
Micro-transactions
!
Registries
!
Multi-signatory contracts (joint savings, forex, trust funds)
!
DACs (Distributed Autonomous Corporations - Ethereum
155
What’s
Next?
Rate of Change Increasing
How many people are online?
1.2
billion
5.0
billion
2010 2020
>50%
Sousveillance
160
THANK YOU
Discussion topics
Jobs
!
Environment
!
Healthcare
!
Finance
Digitize
Disrupt
Demonetize
Democratize
New 
Breakthroughs
Information Layers
Crazy
Entrepreneurs !
Entrepreneurship !
!
Use technology and passion 
to solve a problem
.. and be crazy
EU - Entrepreneurship
Funding
Technology
DIY	

Makers
Ecosystem
Sponsor or partner with a local
fablab or co-working space and
create an environment where
new business ideas are spawned
Eric Migicovsky - Pebble
Seed round: $100k
!
20 investors
!
Raised: $ 0
33
Crowdfunding – Kickstarter
62,986
projects
$227M
invested
44%success
Startup Ecosystems
173
Passion... !
174
Education - from Push to Pull
176
Push to Pull - Khan Academy
21st Century Skills
Education >> Learning
!
!
!
!
!
!
!
!
Teaching >> Mentoring
The Hour of Code
Hour of Code reached twice as many U.S. students as have ever
taken a computer science class
Discussion / Q&A
N E W I N F O R M A T I O N
L A Y E R S
HTML (text) Video
Social Profiles
Location
Quantified Self
Health Data
Sensor Networks
Internet of Things
Software will eat the
world, in all sectors.
Companies need to adapt
or they will become
extinct. In the future
every company will
become a software
company
Mark Andreessen
founder of Netscape,
renowned Venture Capitalist
“
”
source: Yuri van Geest
186
Chris Anderson - Wired
32
Kevin Kelly - Eight Models
!
•Immediacy
•Personalization
•Interpretation
•Authenticity
•Accessibility
•Embodiment
•Patronage
•Findability
Collaborative Consumption!
dilawar	

Disruption. rt @dkberman: Peter Thiel to invest in #Airbnb, valuing at
$2.5B or 40% of all of Hyatt Hotels. http://on.wsj.com/R8zZv0	

10/19/12 11:43 AM	

■ Bartering!
■ Bike sharing!
■ Boats!
■ Book swapping!
■ Carpool/Ride sharing!
■ Car sharing!
■ Clothes swapping!
■ Collaborative workspace!
■ Co-housing!
■ Coworking!
■ Crowd funding!
■ Garden sharing!
■ Fractional ownership!
■ Peer-to-peer lending!
■ Peer-to-peer renting!
■ Product service system!
■ Seed swap!
■ Share taxi!
■ Time banks!
■ LETS!
■ Virtual currency!
The immune system of the company will always attack
- must view it from a biological p.o.v
Very few large organizations can innovate
- most are sales organizations that acquire technology
Important to do, but must report directly to CEO 

and be kept stealth
lessons from brickhouse
A new breed of organizational structure emerging
Examples
- TED
- DonorsChoose
- Xprize
- Singularity University
In each case, a small footprint 
of people/resources is achieving a global impact
exponential orgs
ExOs.. 10x better performance
Founding conference to launch - 10 months
!
GSP09
160 speakers
300 hrs of lectures, workshops, etc
194
Singularity U
Core team - 5 people
Global footprint
2000 alumni
85 countries
local impact
// Started off as ‘just’ a conference
// Several thousand passionate attendees
// Exposed TED Talks on the web
- over a billion views
// Created TEDx events
- over 1200 in just a year
// Scaling the community
ted
// collaborative technologies
// leveraging accelerating technologies
// multi-skilled team - p2p
// fast iterations with f/b loops
// massive, transformative purpose
// scalable (fractal) processes
// extreme distributed authority
// self-regulating, radical process re-engineering
// leverage the crowd (community)
X
attributes of ExOs
ExO 
= 
MTP + SCALE + IDEAS
the ExO formula
MTP
= 
Massive, Transformative, Purpose
the mtp
"Radical breakthroughs for the benefits of humanity"
"Organize the world's information"
"Ideas worth spreading"
"Make invention accessible"
“Positively impact one billion people”
“Open Happiness”
Uniquely yours
Highly Aspirational
Neither narrow nor technology
specific
Aimed at Heart & Mind
Declared with sincerity & confidence
strong MTPs
a weak purpose
Mission
Shape the future of the
Internet by creating
unprecedented value and
opportunity for our
customers, employees,
investors, and ecosystem
partners.
Who? Cisco
“Connect everyone
and everything,
everywhere,
always.”
why an MTP?
// Power of Pull – So Aspirational that a community forms
!
// Helps attract and retain talent
!
// Changes the organizational focus from internal politics to external impact
!
// Helps organize and keep focus during rapid growth
S.C.A.L.E
External Attributes of an ExO
S – Staff on Demand
!
C – Community & Crowd
!
A – Algorithms
!
L – Leased Assets
!
E – Engagement
I.D.E.A.S
Internal Attributes of an ExO
I – Interface Processes
!
D – Dashboards
!
E – Experimentation
!
A – Autonomy
!
S – Social Technologies
Advice to large companies
• Transform leadership (mindset, education)
• Inspire ExOs at edges (via chg mkrs)
• Invest/Partner with adjacent ExOs
• Leverage or expose data
• Hire a ‘Black Ops’ team
• Set up a Google[X] equivalent
X
Current IPP Partners
Before: 75% had little or zero
awareness of breakthroughs
After: 
Game-changing impact (80%
in 2 yrs, 100% in 5 yrs)
!
100% said they had immediate
action items
Advice to large companies
• Transform leadership (mindset, education)
• Inspire ExOs at edges (via chg mkrs)
• Invest/Partner with adjacent ExOs
• Leverage or expose data
• Hire a ‘Black Ops’ team
• Set up a Google[X] equivalent
Advice to large companies
• Transform leadership (mindset, education)
• Inspire ExOs at edges (via chg mkrs)
• Invest/Partner with adjacent ExOs
• Leverage or expose data
• Hire a ‘Black Ops’ team
• Set up a Google[X] equivalent
X
Advice to large companies
• Transform leadership (mindset, education)
• Inspire ExOs at edges (via chg mkrs)
• Invest/Partner with adjacent ExOs
• Leverage or expose data
• Hire a ‘Black Ops’ team
• Set up a Google[X] equivalent
Advice to large companies
• Transform leadership (mindset, education)
• Inspire ExOs at edges (via chg mkrs)
• Invest/Partner with adjacent ExOs
• Leverage or expose data
• Hire a ‘Black Ops’ team
• Set up a Google[X] equivalent
Advice to large companies
• Transform leadership (mindset, education)
• Inspire ExOs at edges (via chg mkrs)
• Invest/Partner with adjacent ExOs
• Leverage or expose data
• Hire a ‘Black Ops’ team
• Set up a Google[X] equivalent
X
Big Companies 
Starting to Catch Up
www.exponentialorgs.com
© 2009, Salim Ismail 14
Powered by progress in computing
216
A"lab"technician"at"Mulago"Hospital"in"Kampala,"Uganda,"looks"under"a"microscope"for"
malaria"parasites."If"parasites"are"found,"the"counter"and"calculator"on"the"le="are"used"
to"determine"how"serious"the"infec?on"is"by"the"number"of"parasites"on"the"the"slide."
(Photo:"Jill"Braden"Balderas)"
Malaria - status quo..
Crédits(:(Marcel(Hommel!
Double(compteur!manuel!souvent!u2lisé!pour!
le!comptage!du!pourcentage!de!globules!
rouges!infectés!sur!un!fro8s!:!le!nombre!de!GR!
infectés!est!compté!sur!l'un!des!compteurs,!le!
nombre!de!GR!sains!sur!l'autre!
Dr. Miguel Luengo-Oroz
D. Tseng, O. Mudanyali, C. Oztoprak,
S.O. Isikman, I. Sencan, O. Yaglidere
and A. Ozcan, “Lensfree Microscopy on
a Cell-phone,” Lab Chip (2010)
Information*
layers*
New$
Breakthroughs$
DIGITIZE
DEMATERIALIZE
DEMOCRATIZE
DEFLATE
SOCIETAL)
DISRUPTON)
)/Political)
)/Financial)
)/Social)
)
)
ABUNDANCE(
The Hype Cycle of Civilization
Industrial!
Revolution
Western!
Society
New leaders
New projects
Discussion / Q&A
October 31, 2000
Thermodynamics & Information	

!
@salimismail
collaborator: 
!
Malcolm Pollack
!
- kung fu master
- Grammy award nominee
- software developer
- philosopher & thinker
!
- www.malcolmpollack.com
!
Thermodynamics & Gas Laws
PV = nRT
Steam
!
!
!
Water
!
!
!
Ice
Gas
No structure
Full expansion
Very fast, very hot
Hard to recapture
Solid
Very structured
Limited expansion
Slow, cold
Liquid
Limited structure
Expands to boundary
Medium fast/‘hot’
Information Technology
PV = nRT
Technology is heating up our world and
vaporizing it..
Messaging
Steam
!
!
!
Water
!
!
!
!
Ice
Money
Steam
!
!
!
Water
!
!
!
Ice
Computing
Steam
!
!
!
Water
!
!
!
Ice
Industries
Steam
!
!
!
Water
!
!
!
Ice
(cold) Water (hot)Ice Steam
Money Goats Paper Money Digital Money
Virtual
Currency
Commerce Physical goods
Information
goods
ideas Attention
Comms Snail mail Email
IM & social
feeds
direct B2B
IT Hardware Software Internet
Cloud
Computing
Biology Inorganic Organic
Complex
lifeforms
Synthetic life
Music Local performer Recorded Music CDs Internet stream
Society Clans or tribes Nation states MNC, FTZ
Facebook or
online grps
Virtual
Currency
Attention
direct B2B
Cloud
Computing
Synthetic life
Internet stream
Facebook
Steam
Gas
No structure, granular
Full expansion into space
Very fast & hot
Hard to recapture
!
Breaks, dissolves
other substances
Technology causing heat to rise
!
Communications reducing space between molecules
!
Everything colliding with everything else
!
We’re all high energy molecules
!
Domain after domain being vaporized
!
Need to be Goldilocks
!
But.. stable structures cannot
form in steam
!
!
!
Need a lot of water
Some ice, some steam
!
- OWS
- Arab spring
- Tea Party
Steam
!
!
!
Water
!
!
!
Ice
240
241
What’s next? 
!
PV = nRT
244
PV = nRT
246
PV = nRT
248
Expand
October 31, 2000
May 25, 2012

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