This document summarizes key points from a presentation on innovations for sustainability and resilience in aquatic systems in Africa. It discusses growing global demand for fish and the opportunity for aquaculture to close the gap between supply and demand. While aquaculture makes up 50% of global fish supply, it only contributes 16% in Africa. The document outlines opportunities for innovation in Africa around genetic improvement of fish species, systems approaches to aquaculture, and taking a livelihoods and systems perspective through Aquatic Agricultural Systems. Partnerships are highlighted as important for making progress on the aquatic agriculture research agenda, which includes sustainable productivity increases, improved market access, resilience, and enabling policies.