At the conclusion of this activity, learners will be able to: define optimal ultrasound transducer position for cross-sectional imaging of nerves; apply surface anatomic landmark identification in ultrasound transducer application; identify sonoanatomy of common peripheral nerves and surrounding structure; and discuss tips and tricks to improve ultrasound images and ultrasound-guided nerve block techniques.
This presentation introduces medical professionals and allied healthcare associates to the fundamental rationale, objectives, techniques, and utilizations of intraoperative neurophysiologic monitoring (IONM).
covers common causes of low back pain, indications and techniques of epidural steroid injections- interlaminar, caudal, transforaminal approaches, both surface landmark and guided methods.
This presentation introduces medical professionals and allied healthcare associates to the fundamental rationale, objectives, techniques, and utilizations of intraoperative neurophysiologic monitoring (IONM).
covers common causes of low back pain, indications and techniques of epidural steroid injections- interlaminar, caudal, transforaminal approaches, both surface landmark and guided methods.
Concepts in Fascial Plane Blocks - What Every Anaesthetist Needs to KnowAmit Pawa
This talk was given at the 2019 European Society of Regional Anaesthesia Meeting in Bilbao, Spain.
In this Talk, we cover the potential mechanisms behind how fascial plane blocks might work and also discuss why there may be such variation in clinical effect.
How I perform my Paravertebral Blocks for breast surgeryAmit Pawa
In October 2019 Dr Pawa Was invited to the Romandie Day of Regional Anaesthesia in Lausanne, Switzerland by Dr Eric Albrecht. He was asked to share some of his tips on siting Paravertebral blocks for Breast Surgery
Point of critical care Ultrasound play a pivotal role in management of critically ill patients admitted in ICU . Its usage in this regard is ever growing . Here we discus about pearls and pitfalls of POCUS in Intensive care medicine.
Fundamentals of Regional Anaesthesia & Plan A BlocksAmit Pawa
This Talk Was delivered by Dr Pawa at the South London Regional Anaesthesia workshop programme Monday 6th December at Guy's Hospital. It features material covered previously, but with updates and QR code links to references
This talk was recorded as part of the Norwich Anaesthesia Update on 13th January 2021.
Here Dr Pawa Discusses the role of fascial plane blocks in modern anaesthetic practice along with key concepts ranging from mechanisms of action, evidence of efficacy and whether they are here to stay.
ESP block - future direction and remaining questionsAmit Pawa
This Talk was delivered by Dr Pawa on 5th June 2021 as part of the ISURA 2021 hybrid conference held in Toronto.
The Future Direction of this block and remaining questions to be answered are covered here
INTRODUCTION:
The recent use of ultrasound imaging in peripheral regional anesthesia allows the operator to see neural structures, guide the needle under real-time visualization, navigate away from sensitive anatomy, and monitor the spread of local anesthetic.
new technique for pain management ,described by dr forero ,it can replace epidural anesthesia,paravertebral anesthesia and other regional blocks.it can be used for both acute and chronic painful conditions
ANESTHETIC CONSIDERATIONS FOR STEREOTACTIC ELECTROENCEPHALOGRAPHY (SEEG) IMP...Anurag Tewari MD
The refractory seizures have significant impact on the quality of life and increase long term neurologic and non-neurologic complications. Implantation of Stereotactic Electroencephalography (SEEG) leads is one of the newer surgical techniques intended to localize seizure foci with higher accuracy than the conventional methods. Most of the commonly utilized anesthetic agents depress EEG waveforms affecting intra operative monitoring during these surgeries. Hence, the anesthetic goals include a stable induction and maintenance with agents which have minimal effect on EEG. This article discusses the peri-operative considerations of multiple anti-epileptic medications, recent advances in anesthetic management, and important post-operative concerns.
Keywords: Anesthesia, epilepsy surgery, intra-operative EEG, intra operative monitoring, refractory seizures, SEEG, seizure foci, stereotactic electroencephalography
I am a physician, clinical researcher, and educator. I am also on Twitter and tweet under the handle @EMARIANOMD. Naturally you may ask: “How does Twitter fit into a physician’s academic career?” These slides were part of an interactive workshop presented at the 2016 American Society of Anesthesiologists Annual Meeting "Social Media Bootcamp." Please see my blog http://www.edmariano.com/archives/926 for additional information.
There are currently few options to extend the duration of regional analgesia at home beyond the one day expected from most single-injection nerve blocks. Continuous peripheral nerve block (CPNB) with a plain local anesthetic perineural infusion is the most established way to provide days of postoperative pain control and allows titration, but training in insertion techniques and a system to manage ambulatory CPNB patients are necessary. Adjuvants or depot formulations of local anesthetics may offer potential options for limited extension of block duration, but further studies regarding efficacy and safety for regional anesthesia as well as comparative-effectiveness versus CPNB are necessary.
At the conclusion of this activity, learners will be able to: discuss the indications for continuous peripheral nerve blocks; identify obstacles to implementing a continuous peripheral nerve block system; examine various techniques and equipment for continuous peripheral nerve block performance; and discuss the application of ultrasound guidance for perineural catheter insertion.
Concepts in Fascial Plane Blocks - What Every Anaesthetist Needs to KnowAmit Pawa
This talk was given at the 2019 European Society of Regional Anaesthesia Meeting in Bilbao, Spain.
In this Talk, we cover the potential mechanisms behind how fascial plane blocks might work and also discuss why there may be such variation in clinical effect.
How I perform my Paravertebral Blocks for breast surgeryAmit Pawa
In October 2019 Dr Pawa Was invited to the Romandie Day of Regional Anaesthesia in Lausanne, Switzerland by Dr Eric Albrecht. He was asked to share some of his tips on siting Paravertebral blocks for Breast Surgery
Point of critical care Ultrasound play a pivotal role in management of critically ill patients admitted in ICU . Its usage in this regard is ever growing . Here we discus about pearls and pitfalls of POCUS in Intensive care medicine.
Fundamentals of Regional Anaesthesia & Plan A BlocksAmit Pawa
This Talk Was delivered by Dr Pawa at the South London Regional Anaesthesia workshop programme Monday 6th December at Guy's Hospital. It features material covered previously, but with updates and QR code links to references
This talk was recorded as part of the Norwich Anaesthesia Update on 13th January 2021.
Here Dr Pawa Discusses the role of fascial plane blocks in modern anaesthetic practice along with key concepts ranging from mechanisms of action, evidence of efficacy and whether they are here to stay.
ESP block - future direction and remaining questionsAmit Pawa
This Talk was delivered by Dr Pawa on 5th June 2021 as part of the ISURA 2021 hybrid conference held in Toronto.
The Future Direction of this block and remaining questions to be answered are covered here
INTRODUCTION:
The recent use of ultrasound imaging in peripheral regional anesthesia allows the operator to see neural structures, guide the needle under real-time visualization, navigate away from sensitive anatomy, and monitor the spread of local anesthetic.
new technique for pain management ,described by dr forero ,it can replace epidural anesthesia,paravertebral anesthesia and other regional blocks.it can be used for both acute and chronic painful conditions
ANESTHETIC CONSIDERATIONS FOR STEREOTACTIC ELECTROENCEPHALOGRAPHY (SEEG) IMP...Anurag Tewari MD
The refractory seizures have significant impact on the quality of life and increase long term neurologic and non-neurologic complications. Implantation of Stereotactic Electroencephalography (SEEG) leads is one of the newer surgical techniques intended to localize seizure foci with higher accuracy than the conventional methods. Most of the commonly utilized anesthetic agents depress EEG waveforms affecting intra operative monitoring during these surgeries. Hence, the anesthetic goals include a stable induction and maintenance with agents which have minimal effect on EEG. This article discusses the peri-operative considerations of multiple anti-epileptic medications, recent advances in anesthetic management, and important post-operative concerns.
Keywords: Anesthesia, epilepsy surgery, intra-operative EEG, intra operative monitoring, refractory seizures, SEEG, seizure foci, stereotactic electroencephalography
I am a physician, clinical researcher, and educator. I am also on Twitter and tweet under the handle @EMARIANOMD. Naturally you may ask: “How does Twitter fit into a physician’s academic career?” These slides were part of an interactive workshop presented at the 2016 American Society of Anesthesiologists Annual Meeting "Social Media Bootcamp." Please see my blog http://www.edmariano.com/archives/926 for additional information.
There are currently few options to extend the duration of regional analgesia at home beyond the one day expected from most single-injection nerve blocks. Continuous peripheral nerve block (CPNB) with a plain local anesthetic perineural infusion is the most established way to provide days of postoperative pain control and allows titration, but training in insertion techniques and a system to manage ambulatory CPNB patients are necessary. Adjuvants or depot formulations of local anesthetics may offer potential options for limited extension of block duration, but further studies regarding efficacy and safety for regional anesthesia as well as comparative-effectiveness versus CPNB are necessary.
At the conclusion of this activity, learners will be able to: discuss the indications for continuous peripheral nerve blocks; identify obstacles to implementing a continuous peripheral nerve block system; examine various techniques and equipment for continuous peripheral nerve block performance; and discuss the application of ultrasound guidance for perineural catheter insertion.
Overview of the anatomical pathways of acute and chronic pain, detailed explaination of the synapse, and summary of various types of pharmacological agents for chronic pain
How do we as anesthesiologists address the need for acute pain medicine physicians and have a positive impact on the patient experience? We can take the lead in developing multimodal perioperative pain management protocols. Anesthesiologists can also add value through cost savings for the hospital. More effective pain management can prevent inadvertent admissions or readmissions due to pain. In addition, an effective multimodal analgesic protocol can directly or indirectly prevent hospital-acquired conditions (HACs). HACs are considered by CMS to be “never events” and supposedly preventable (4); hospitals reporting HACs as secondary diagnoses are not entitled to Medicare or Medicaid payments for related care.
this is an important topic in palliative care. a form of care each of us may need when we suffer terminal illness and severe trauma at one point in our life time.
Knee replacement is one of the most commonly performed operations in the United States with over 700,000 procedures performed annually. In 2012, the American Society of Anesthesiologists (ASA) published its guidelines for acute pain management in the perioperative setting. This document recommends “multimodal analgesia” which means that two or more classes of pain medications or therapies, working with different mechanisms of action, should be used in the treatment of acute pain. The ASA also strongly recommends the use of regional analgesic techniques as part of the multimodal analgesic protocol when indicated.
At the conclusion of the activity participants should be able to: discuss the value-based purchasing program and its components; identify aspects of the HCAHPS survey that directly and indirectly relate to inpatient pain management; and apply strategies to provide high quality pain management and minimize risks for postsurgical patients.
What is laser; Its uses in dermatology; Types of lasers; Treatment options for acne scars, melasma; hyper pigmentation; wrinkles; warts; Dark skin, facial rejuvenation; stains; rosacea; hair removal options;
Histology Made Easy: The cell membrane; Semi permeable membrane; fluid Mosaic...DrSaraHistology
The easiest Way to learn the core principles of Cell membrane. Its semi permeable nature; the fluid mosaic model and the Different membrane proteins. How substances are transferred across the membrane. The importance of simple diffusion, facilitated diffusion, active transport, endocytosis , and exocytosis.
Cervical Arthritis, Cervical Spondylotic Myelopathy by Pablo Pazmino MDPablo Pazmino
This video explains Cervical Stenosis and Cervical Spondylosis/Arthritis. When stenosis begins to affect the spinal cord this is called Cervical Spondylotic Myelopathy. This video highlights the history, epidemiology, and treatment options both conservative and surgical. If you or someone you know needs to be seen in regards to Cervical Stenosis/Arthritis feel free to look us up online www.beverlyspine.com or www.santamonicaspine.com OR call toll free 1-8SPINECAL-1
This video explains Cervical Stenosis and Cervical Spondylosis/Arthritis. When stenosis begins to affect the spinal cord this is called Cervical Spondylotic Myelopathy. This video highlights the history, epidemiology, and treatment options both conservative and surgical. If you or someone you know needs to be seen in regards to Cervical Stenosis/Arthritis feel free to look us up online www.beverlyspine.com or www.santamonicaspine.com OR call toll free 1-8SPINECAL-1
EDIC is pleased to announce a webinar with Dr. R. Bruce Donoff, the Dean at Harvard Dental School. Dr. Donoff’s presentation will cover the risk factors for inferior alveolar and lingual nerve injury after third molar extraction, as well as the proper documentation and follow up of nerve injuries. Dr. Donoff will also discuss the potential for recovery from paresthesia after surgical intervention. The webinar will be held on May 10, 2011 at 7:00 PM.
In this #RAUK21 clinical symposium presentation discussing perioperative care of patients having hip surgery, I discuss the opioid epidemic, the goal of personalizing pain management through better understanding of pain trajectories, multimodal analgesia, ways to promote opioid safety, and opportunities to improve patient care through transitional pain services.
For this #RAUK21 clinical symposium presentation, I present anesthesia and pain management considerations for short-stay knee arthroplasty including patient selection criteria, intraoperative anesthetic technique, multimodal analgesia, and nerve block options.
In this presentation that I gave at the 2021 Association of Anaesthetists Winter Scientific Meeting, I proposed the reimagination of training in regional anaesthesia into three stages: core training, advanced training, and innovation.
I had the honor of being a keynote lecturer at the 2021 Association of Anaesthetists Winter Scientific Meeting. For this talk, I provided some historical background on various contributing factors to the U.S. opioid epidemic, the current state including the many legislative and regulatory responses, and potential opportunities to innovate in clinical care moving forward.
I gave this talk at the 2020 Winter Anesthesiology Meeting of the California Society of Anesthesiologists (#CSAHSWinter20).
My objectives were to:
1. Discuss adjuvants for extending single-injection nerve block duration;
2. Provide an update on continuous peripheral nerve blocks; and
3. Address practical considerations and present a strategy for personalized postoperative pain medicine.
Interfascial Plane Blocks Offer an Acceptable Alternative to Thoracic Epidura...Edward R. Mariano, MD
This was part of a debate held at #ANES20 (recording available from ASA) between me and Dr. Jeff Gadsden from Duke University School of Medicine. Dr. Gadsden and I clashed on the same topic last year at #ANES19 during which I promoted thoracic epidural analgesia, and Dr. Gadsden made the case for interfascial plane blocks. This year we switched sides! Link to my slides from #ANES19: https://www.slideshare.net/EdwardRMariano/thoracic-epidural-analgesia-is-the-gold-standard-for-major-abdominal-surgery
The objectives of this session were as follows:
1. Discuss multimodal pain management strategies in the context of enhanced recovery programs;
2. Discuss advantages and disadvantages of thoracic epidural analgesia for major abdominal surgery in the context of enhanced recovery programs;
3. Discuss advantages and disadvantages of truncal somatic blocks in the context of enhanced recovery programs; and
4. Discuss developing safe and effective procedure specific pain management strategies for major abdominal surgery.
Dealing with the Information Firehose: Tips for Busy ResearchersEdward R. Mariano, MD
I gave this presentation as part of a panel called "The Modern Learner" at the 2019 spring annual meeting of the American Society of Regional Anesthesia and Pain Medicine.
After participating in this educational activity, participants should be able to:
1. Identify available online tools that can be used for lifelong learning and continuing professional development;
2. Discuss ways that free platforms like PubMed and Google Scholar can be used to improve the efficient and timely delivery of new research.
Here are the slides from my #CSAHSWinter20 lecture "Designing the "Best" Pain Management Plan for Knee Replacement.
Upon completion of this presentation, participants will be able to:
1. Define elements of multimodal analgesia;
2. Present innervation of the knee joint; and
3. Discuss peripheral nerve block options that can be included in a multimodal analgesic plan for TKA patients.
By the end of this lecture, participants should be able to:
1. Present the role of physicians as advocates;
2. Discuss social media platforms; and
3. Provide examples of physician leadership through communication and advocacy.
By the end of this lecture, the learner will be able to:
1. Review the anatomy and techniques for new interfascial plane blocks;
2. Discuss the evidence for these regional analgesic procedures; and
3. Present an approach to evaluate new techniques.
By the end of this presentation, learners will be able to:
1. Discuss the current state of the opioid epidemic;
2. Review the role of opioids in anesthesia and perioperative care; and
3. Assess the value of opioid-free strategies.
At the 2019 Society for Education in Anesthesia fall meeting, I was invited to present ways to modernize the traditional curriculum vitae (CV) by creating a digital portfolio. By the end of this talk, learners will be able to: 1) digitize their CVs and update them into living documents; 2) utilize free online platforms for creation of a digital portfolio; and 3) augment the CV with an educator portfolio for academic faculty members primarily engaged in clinical teaching.
Thoracic Epidural Analgesia is the Gold Standard for Major Abdominal SurgeryEdward R. Mariano, MD
At Anesthesiology 2019, the annual meeting of the American Society of Anesthesiologists (#ANES19), I debated Dr. Jeff Gadsden from Duke on the topic of whether or not thoracic epidural analgesia is the gold standard for major abdominal surgery. Dr. Vijay Gottumukkala organized and moderated the debate and assigned sides: pro (me) and con (Jeff).
Physicians need to be active on social media and other communication platforms to offset the noise of the anti-science movement. I am speaking at the New Zealand Anaesthesia Annual Scientific Meeting in Queenstown this week [August 21-24, 2019] on the role of social media and medicine. There has been a growing anti-science movement, and physicians have a moral imperative to stand up for science and evidence-based treatments.
“Surveys show that physicians are one of the most trusted professions in the eyes of the public. Yet most people in the world today get their information, including health information, from the internet. We have to be there to offset the noise. We can’t ignore where our patients get their information, and we can join the conversation.”
Social media also offers a way for doctors to keep up-to-date with the latest research and new treatments. One example is the exponential growth of regional anaesthesia. Regional anaesthesia allows procedures to be done without the patient being unconscious and can provide targeted pain relief.
“We have more tools at our disposal. New blocks are being performed and described every month and it’s hard to keep up with the literature. Social media allows you to be part of a learning community made up of people who have similar interests and it can curate information for you.”
The clinical practice of regional anesthesia has evolved over time into a true medical subspecialty incorporating acute pain medicine. Advancing the science of regional anesthesiology and acute pain medicine will require identifying research priorities and meaningful outcomes. There are tremendous opportunities to develop new applications of regional anesthesiology and acute pain medicine that may improve patient experience, public health, and healthcare value.
By the end of this lecture, learners will be able to:
1. Discuss current problems related to perioperative pain medicine and access to regional anesthesia;
2. Apply strategies to provide consistent high quality pain management for postsurgical patients; and
3. Identify opportunities to improve outcomes that matter to patients.
I hosted this seminar as part of the Emerging Leaders Development Program at the VA Palo Alto Health Care System.
Goal: To familiarize participants with the challenges and best practices of coaching and developing employees. Through discussion and instruction, participants will understand the importance of providing employees with personal guidance that will allow them to acquire new skills, advance professionally, and improve patient and customer outcomes.
Upon completion of this presentation, participants will be able to:
1. Discuss the challenge of losing identity and apply strategies to establish a brand;
2. Review missed opportunities in adopting new technology and identify potential applications in future operating room models;
3. Understand barriers to change implementation and develop a team approach that redefines challenges as opportunities.
This is the slide deck I used for my invited lecture at the 2018 European Society of Regional Anaesthesia and Pain Therapy annual meeting in Dublin, Ireland.
After participating in this educational activity, participants should be able to:
1) Identify available online tools that can be used for lifelong learning and continuing professional development;
2) Discuss ways social media platforms can be used to enhance the scientific conference experience; and
3) Apply practical and free Twitter tools available to any new user.
By the end of this lecture, learners will be able to:
1. Discuss current problems related to perioperative pain medicine and access to regional anesthesia;
2. Identify ways to personalize pain medicine;
3. Compare currently available methods to extend nerve block duration including adjuncts and continuous peripheral nerve blocks; and
4. Identify opportunities to improve outcomes that matter to patients.
The Joint Replacement Bundle: Implications for Patients and Acute Pain ServicesEdward R. Mariano, MD
In this presentation, we will review the likely trends in healthcare going forward, including bundled payment programs. We will define the two major bundled payment programs involving joint replacement and discuss opportunities for acute pain services to add value.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
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2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Surface anatomy and sonoanatomy for the occasional regional anesthesiologist
1. Surface Anatomy and
Sonoanatomy for the Occasional
Regional Anesthesiologist
@EMARIANOMD@EMARIANOMD
Edward R. Mariano, M.D., M.A.S.Edward R. Mariano, M.D., M.A.S.
Professor of Anesthesiology, Perioperative & Pain MedicineProfessor of Anesthesiology, Perioperative & Pain Medicine
Stanford University School of MedicineStanford University School of Medicine
Chief, Anesthesiology and Perioperative CareChief, Anesthesiology and Perioperative Care
Veterans Affairs Palo Alto Health Care SystemVeterans Affairs Palo Alto Health Care System
2. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Financial Disclosures
Halyard Health, B Braun – Unrestricted
educational program funding paid to my
institution
The contents of the following presentation are
solely the responsibility of the speaker
without input from any of the above
companies.
3. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Disclaimer
This presentation is intended for educational
purposes only and is not meant to be
reproduced or redistributed for commercial
purposes
4. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Learning Objectives
Define optimal ultrasound transducer position
for cross-sectional imaging of nerves
Apply surface anatomic landmark
identification in ultrasound transducer
application
Identify sonoanatomy of common peripheral
nerves and surrounding structures
Discuss tips and tricks to improve ultrasound
images and block techniques
5. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
How Hard Can It Be?
NYSORA.COM
-
7. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Lesson #2
Regional anesthesia isRegional anesthesia is
applied anatomyapplied anatomy
8. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
History of Nerve Localization
Anatomic landmarks
Fascial clicks or pops
Electrical nerve
stimulation
Sustained “twitch” at <
0.5 mA current
suggests appropriate
needle position
Ultrasound
9. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Overview
Introduction to ultrasound
Surface anatomic landmarks
Relevant gross anatomy
Traditional nerve block techniques
Sonoanatomy for nerve blocks
10. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Overview
Introduction to ultrasound
Surface anatomic landmarks
Relevant gross anatomy
Traditional nerve block techniques
Sonoanatomy for nerve blocks
11. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Basic Sonoanatomy
Blood vessels:
hypo-echoic (dark)
Muscles: hypo- >
hyper-echoic
(striations)
Bone and fascia:
hyper-echoic
(white)
Nerves: hypo-
echoic
Connective tissues are hyper-Connective tissues are hyper-
echoic (epineurium, perineurium)echoic (epineurium, perineurium)
12. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
A Closer Look at the Nerve
Short-Axis ViewShort-Axis View
13. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
The “A.R.T.” of Target Imaging
A lignment
Rotation
Tilt
14. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Alignment: Where Do We Look?
15. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Optimal Rotation
16. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Optimal Rotation
19. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Overview
Introduction to ultrasound
Surface anatomic landmarks
Relevant gross anatomy
Traditional nerve block techniques
Sonoanatomy for nerve blocks
20. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Interscalene Block: How We Did It
Needle inserted in IS
groove at C6
Antero-lateral approach
Needle angle 30-45º
Elicit motor response
(deltoid, biceps, triceps,
pectoralis)
Borgeat A, et al. Anesth 2003:99:436Borgeat A, et al. Anesth 2003:99:436
21. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Interscalene Anatomy
Position: supine with
head turned away
SCM clavicular head
Interscalene groove
posterior to SCM at
cricoid level (C6)
External jugular vein
Subclavian artery
SCMSCM
Subclavian ArtSubclavian Art
CricoidCricoid
22. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Interscalene Sonoanatomy
Transverse Short-Axis ViewTransverse Short-Axis View
SC
M
AS
M MS
M
CTP
BP
Mariano ER, et al. JUM 2010;29:329Mariano ER, et al. JUM 2010;29:329
23. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Infraclavicular Block: How We Did It
Insertion 2 cm
medial and 2 cm
caudad to CP
Needle inserted
plumb-bob
Avg depth
4.24±1.49 cm in
men, 4.01±1.29 cm
in women
Wilson JL, et al. A&A 1998;87:870Wilson JL, et al. A&A 1998;87:870
24. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Infraclavicular Anatomy
Position: supine with
arm at side or
abducted 90°
Palpate coracoid
process below the
clavicle
Plexus runs under
coracoid process
CoracoidCoracoid
Clavicle
Clavicle
25. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Infraclavicular Sonoanatomy
Transverse Short-Axis ViewTransverse Short-Axis View
PMa
PMi
AA AVN
N
N
Mariano ER, et al. JUM 2009;28:1211Mariano ER, et al. JUM 2009;28:1211
26. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Femoral Nerve Block: How We Did It
Needle insertion:
lateral to artery at
45° angle aiming
cephalad
Feel 2 “pops”
Proper motor
response = quad
contraction
Ilfeld, BM, et al. Anesth 2008;108:703Ilfeld, BM, et al. Anesth 2008;108:703
27. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Femoral Anatomy
Position: supine with
roll under hip
Leg straight
Inguinal crease
Femoral artery
Femoral nerve is
lateral to femoral
artery
Inguinal C
rease
Inguinal C
rease
28. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Femoral Sonoanatomy
Transverse Short-Axis ViewTransverse Short-Axis View
FA
FL
FIIliacus
N
Mariano ER, et al. JUM 2009;28:1453Mariano ER, et al. JUM 2009;28:1453
29. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Adductor Canal Anatomy
Position: supine with
thigh externally rotated
and knee slightly flexed
Subsartorial tunnel
begins distal to the apex
of the femoral triangle
Saphenous nerve runs
with superficial femoral
artery
Horn JL, et al. RAPM 2009;34:486Horn JL, et al. RAPM 2009;34:486
Manickam B, et al. RAPM 2009;34:578Manickam B, et al. RAPM 2009;34:578
30. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Adductor Canal Ultrasound
Transducer placed
along medial aspect
of thigh distal to
inguinal crease
Short-axis view
Landmarks
Sartorius muscle
Saphenous (N)
Femoral artery (A) Mariano ER, et al. JUM 2014;33:1653Mariano ER, et al. JUM 2014;33:1653
Sartorius
N A
31. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Popliteal Fossa Block: How We Did It
Insertion site: 8-10
cm cephalad to
popliteal crease or
at intertendinous
junction
4” needle angled
45° cephalad
Plantar flexion or
inversion preferred
Hadzic A, et al. A&A 2002;94:1321Hadzic A, et al. A&A 2002;94:1321
32. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Popliteal Anatomy
Position: prone with
knee slightly flexed
Popliteal crease
Biceps femoris
laterally
Semimembranosus
and semitendinosus
medially
Intertendinous
“junction”
BicepsFemoris
BicepsFemoris
Semi-M/TSemi-M/T
33. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Popliteal Sonoanatomy
Transverse Short-Axis ViewTransverse Short-Axis View
F
BF
N
Mariano ER, et al. RAPMMariano ER, et al. RAPM
34. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Transversus Abdominis Plane Anatomy
35. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
TAP Sonoanatomy
Transverse Short-Axis ViewTransverse Short-Axis View
EO
IO
TA
36. Surface Anatomy and SonoanatomySurface Anatomy and Sonoanatomy
Summary
We defined optimal ultrasound transducer
position for cross-sectional imaging of nerves
We applied surface anatomic landmark
identification in ultrasound transducer
application
We identified sonoanatomy of common
peripheral nerves and surrounding structures
We discussed tips and tricks to improve
ultrasound images and block techniques