This document provides guidelines for stress ulcer prophylaxis including recommended agents, their dosages, and drug families. It recommends first line agents as H2 blockers like ranitidine, famotidine, cimetidine or proton pump inhibitors like omeprazole, lansoprazole, pantoprazole. Second line agents include cytoprotectives like sucralfate or antacids containing aluminum hydroxide, magnesium hydroxide or calcium carbonate. The document lists the dosage for each recommended medication for both oral and intravenous administration.

1. STRESS ULCER PROPHYLAXIS
DR AYMAN SOBHY RAMAH
MEEQAT GENERAL HOSPITAL
MADINA,KSA

25. dose Agent family
3oo mg orally or IV Q 6-8
H
20 mg twice daily orally OR
IV
150 mg twice daily(oral)
50 mg every 6-8 hours(IV)
-
cimetidine,
famotidine
ranitidine
nizatidine
H2 blockers
40 mg orally
30mg PO Q24 Hours
40 mg (Q12-24h)IV or orally
20-40 mg
omeprazole,
lansoprazole,
pantoprazole,
esomeprazole
Proton pump inhibitors
1 gram four times per day
orally
Sucralfate cytoprotectives
300 mg tab
150 mg tab
1-2 tablets
Aluminum hydroxide
magnesium hydroxide
Calcium carbonate
Antacids