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Introduction
Social isolation refers to “a state in which an individual lacks
a sense of belonging socially, lacks engagement with others, has a
minimal number of social contacts and they are deficient in fulfilling
quality relationships” [1]. It could be seen either as a potential cause
or symptom of an emotional/psychological disorder (John Hopkins
University, 2013; University of Texas Health County Psychiatric
Centre, 2008). Social relationships are integral to the human well-
being and are critically involved in the maintenance of health [2].
Social network and support among other factors affect the quality
of life of elderly people [3]. Numerous studies have shown that
people who have satisfying relationships with family, friends and
their community are happier, have less health challenges and live
longer. On the contrary, a relative lack of social connections has
been linked with depression and later-life cognitive decline [4]. In
1988, House, Landis and Umberson found that social relationships
had as much impact on physical health as blood pressure, smoking,
physical activity and obesity, therefore, the effects of social network
size on health are robust. Broadly speaking, there are three
distinct ways through which social ties work to influence health:
behavioural, psychological and physiological [5]. Human beings are
naturally sociable; feeling isolated can often have a negative impact
on our health holistically. Therefore, keeping in touch with friends
and families can be beneficial for our well-being.
The negative impact of social isolation
Social isolation is often discussed in conjunction with loneliness
as both concepts are often used synonymously in everyday
language although they tend to be different in some respects.
Similar to loneliness, social isolation is multidimensional because
it encompasses physical, mental-health, psychological, and social
dimensions [6]. The health implications of social isolation are well
documented in relevant literatures; for instance, a meta-analysis
carried out by Holt-Lunstad, Smith & Layton involving one hundred
and forty eight (148) studies, between 1900 and 2007 revealed
that elderly individuals who have unsatisfactory or limited social
relationships have an increased mortality risk than people with
stronger social networks. It was also found that loneliness and
social isolation are associated with an increased risk of developing
coronary heart disease and stroke [7]. Other adverse effects that
could result from social isolation include increased blood pressure,
abnormal stress response, heart disease and poor sleep [8].
Social isolation has been directly linked to aging, in recognition
that growing older presents increased risks of ending up alone
through death of a spouse [9]. The aging process involves the
progressive functional decline, or a gradual deterioration of
physiological function with age, including a decrease in fecundity
[10]. It represents the closing period in one’s lifespan when an
individual reflects on his/her life and begins to finish off his life
course [11]. This inevitable stage in a man’s life is undoubtedly
associated with a spectrum of physiological changes that not
only limit our normal functions but render us more susceptible
to diseases and ultimately death. One of the psychological/social
issues possible as one ages is decreased social contact which
may ultimately lead to social isolation. This affects the health
Ogundiran Opeyemi Olufemi*
Department of Physiotherapy, Obafemi Awolowo University Teaching Hospital, Nigeria
*Corresponding author: Ogundiran Opeyemi Olufemi, Department of Physiotherapy, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun
State, Nigeria, Tel: +234807083440031; Email:
Submission: December 06, 2017; Published: December 18, 2017
Social Isolation in the Elderly; Physical Activity to the
Rescue
Opinion Degenerative Intellect Dev Disabil
Copyright © All rights are reserved by Ogundiran Opeyemi Olufemi.
CRIMSONpublishers
http://www.crimsonpublishers.com
Abstract
Human beings are naturally sociable, and this evidence can be seen in the establishment of many types of relationships among them. There are
endless benefits associated with social interactions which are critical to the maintenance of optimal health. A socially-isolated individual usually lacks a
sense of belonging among his or her peers which could inevitably lead to depression or its associated symptoms especially in the geriatric population.
The problem of social isolation among older adults is emerging due to several risk factors. The major aim of this opinion article is to critically examine
the relevance of physical activity in tackling social isolation among the elderly.
Keywords: Elderly; Social isolation; Social interactions
How to cite this article: Ogundiran O O. Social Isolation in the Elderly; Physical Activity to the Rescue. Dev Disabil: 1(1): DIDD.000502. 2017.
Degenerative Intellectual & Developmental Disabilities
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Degenerative Intellect Dev Disabil
and behavioural habits of elderly persons. For instance, an older
person’s social network can impact his or her health positively
through encouragement to adhere to a medical treatment or to
abstain from negative and risky behaviours [12].
Increased social engagement as measured by the frequency
of late-life social activities in older individuals is associated with
longevity and a decreased risk of dementia, while being lonely has
been linked with disability and an accelerated rate of motor decline
[13]. In fact, older people who are lonely tend to experience decline
in their mobility than those who are not and are also likely to die
sooner [14].
Loneliness is a growing problem in older adults and risk factors
such as lack of access to private transport, minimal or no contact
with friends and family, low morale and living alone have made
elderlyindividualsvulnerabletoit[15].Thereisastrongcorrelation
with malnutrition, repeated hospitalization, cognitive regression
and grave alcoholic problem [16]. In Nigeria, urbanization and
changes to the family structure are being touted as factors leading
to social isolation of the elderly [17]. The population of older adults
is increasing rapidly with people with aged sixty and older currently
making up 12.3 per cent of the global population. It is estimated
that the number will rise to almost 22 per cent by the year 2050
[18]. With this in mind, social isolation will likely impact the health,
well-being, and quality of life of numerous elderly persons now
and in the foreseeable future. The value of elderly persons to the
society cannot be overemphasized especially in conflict resolutions
within families and communities, care giving, volunteering, and
passing of cultural traditions to younger generations. Consequently,
in developed societies such as the US and UK, many government
policies, programmes and interventions are already being geared
towards limiting the vulnerability of these senior citizens to
inevitable developments associated with ageing.
Tackling social isolation through research
Several studies have been carried out in order to address the
problem of social isolation with some explicitly targeting lonely
elderly individuals while others did not focus on them. A systematic
reviewdonebyDickens,Richards,Greaves&Campbell[19]involving
thirty two (32) studies (16 randomized controlled trials and 16
quasi-experimentalstudies)focusedontheeffectivenessofdifferent
“social” interventions for alleviating social isolation in older people.
It was however concluded from this review that additional quality
research studies on the effectiveness of these social interventions
are required in order to improve the evidence base. According to
another review by Cohen-Mansfield & Perach [20] involving thirty
four (34) studies examining the utility of loneliness interventions
among older persons, it was suggested that it is possible to
reduce social isolation by using educational interventions focused
on social networks maintenance and enhancement. A recent
systematic review by Robins, Jansons & Haines [21] investigated
the impact of physical activity interventions on social isolation
among community-dwelling older adults. A methodologically
inclusive review of existing literature yielded a total of seventeen
(17) studies due to the dearth of randomized controlled trials
examining the effect of physical activity interventions on social
isolation of elderly people. The results of this review suggested that
group physical activity interventions are associated with decreases
in social isolation among community-dwelling older adults.
In adults aged 65 years and above, physical activity includes
leisure time activities such as walking, dancing, gardening, hiking,
swimming, household chores, games, sports, or planned exercise
[22]. Increasing physical activity levels is one of the most efficacious
interventions to improve health in populations [23], psychosocial
health inclusive. Many activity/exercise programs have been
designed for elderly persons in a bid to reduce isolation and its
consequences [24]. Examples of these programs are: active choices,
active living every day, enhance fitness, enhance wellness, fit and
strong, healthy moves for ageing, and walk with ease [25]. These
programs are low cost initiatives and have been implemented
in existing community and senior centres; they have also been
found to be sustainable and replicable in many urban and rural
communities.
Discussion/Conclusion
Asinthecaseofyoungeradults,regularexercisehasbeenshown
to provide myriad of benefits in elderly persons with evidence-
base improvements in cardiovascular, metabolic, endocrine and
psychological (which is the most relevant in this article) health
[26-30]. These physical activities/exercises shouldn’t be strenuous
because of comorbidities associated with advanced age however,
encouraging elderly persons to remain active in their hobbies and
interests remains one of the most viable ways of nullifying the
negative effects of loneliness. Tackling social isolation among our
ageing population is a great challenge we cannot underestimate,
both at individual and community levels, therefore, physical activity
specifically regular exercise is a promising, non-pharmaceutical
intervention to prevent and manage loneliness and other age-
related diseases in our senior citizens [31,32].
References
1.	 Nicholson N (2009) Social isolation in older adults: an evolutionary
concept analysis. J Adv Nurs 65(6): 1342-1352.
2.	 Holt-Lunstad J, Smith TB, Layton JB (2010) Social relationships and
mortality risk: A meta-analysis review. PLOS Med 7(7): e1000316.
3.	 Everard KM, Lach HW, Fisher EB, Baum MC (2000) Relationship of
activity and social support to the functional health of older adults. J
Gerontol B psychol Sci Soc Sci 55(4): S208-S212.
4.	 Harvard Medical School (2010) The health benefits of strong
relationship. Harvard Health Publications, USA.
5.	 House JS, Landis KR, Umberson D (1988) Social relationships and
Health. Science 241(4865): 540-545.
6.	 Keefe J, Andrew M, Fancey P, Hall M (2006) Final report: A profile of
social isolation in Canada, pp. 1-42.
7.	 Valtorta N, Kanaan M, Gilbody S, Hanratty B (2016) Loneliness and social
isolation as risk factors for coronary heart disease and stroke: systematic
review and meta-analysis of longitudinal observational studies. Heart,
pp. 308790.
How to cite this article: Ogundiran O O. Social Isolation in the Elderly; Physical Activity to the Rescue. Dev Disabil: 1(1): DIDD.000502. 2017. 3/3
Degenerative Intellect Dev DisabilDegenerative Intellectual & Developmental Disabilities
8.	 Luanaigh CO, Lawlor BA (2008) Loneliness and the health of older
people. Int J Geriatr Psychiatry 23(12): 1213-21.
9.	 Edelbrock D, Buys L, Waite L, Grayson D, Broe A, et al. (2001)
Characteristics of social support in a community-living sample of older
people: The Sydney Older Persons Study. Australasian Journal on Ageing
20(4): 173-178.
10.	Lopez-Otin C, Blasco M, Partridge L, Serrano M, Kroemer G (2013) The
hallmarks of aging. Cell 153(6): 1194-1217.
11.	Warnick J (1995) Listening with different ears: counselling people over
sixty. QED Press, Ft Bragg, CA USA.
12.	BerkmanL,GlassT,BrissetteI,SeemanTE(2000)Fromsocialintegration
to health: Durkeim in the new millennium. Soc Sci Med 51(6): 843-857.
13.	Fratiglioni L, Paillard-Borg S, Winblad B (2004) An active and socially
integrated Lifestyle in late life might protect against dementia. Lancet
Neurol 3(6): 343-53.
14.	Perissinotto CM, Stijacic CI, Covinsky KE (2012) Loneliness in older
persons: a predictor of functional decline and death. Arch Intern Med
172(14): 1078-1083.
15.	Victor C, Schambler S, Bond J, Bowling A (2000) Being alone in later life:
Loneliness, isolation and living alone in later life. Reviews in clinical
Gerontology 10(4): 407-410.
16.	Cacioppo JT, Hawkley LC (2009) Perceived social isolation and cognition.
Trends Cogni Sci (10): 447-454.
17.	Gureje O, Kola L, Afolabi E, Olley B (2010) Determinants of quality of life
of elderly Nigerians: results from the Ibadan study of ageing. Afr J Med
Med Sci 37(3): 239-247.
18.	United Nations Population Fund (2015) Ageing.
19.	Dickens AP, Richards SH, Greaves CJ, Campbell JL (2011) Interventions
targeting social isolation in older people: a systematic review. BMC
Public Health 15: 11-647.
20.	Cohen-Mansfield J, Perach R (2015) Interventions for alleviating
loneliness among older persons: a critical review. Am J Health Promot
29(3): e109-125.
21.	Robins L, Jansons P, Haines T (2016) The impact of physical activity
interventions on social interventions on social isolation among
community-dwelling older adults: a systematic review. Research &
Reviews: Journal of Nursing and Health Science 2(1): 62-71.
22.	World Health Organization (2016) WHO Physical activity and older
adults.
23.	Paterson DH, Jones GR, Rice CL (2007) Aging and physical activity:
evidence to develop exercise recommendations for older adults. Can J
Public Health 98(Suppl 2): S69-108.
24.	Coyle C, Dugan E (2012) Social isolation, loneliness and health among
older adults. J Aging Health 24(8): 1346-1363.
25.	National Council on Aging (2016) Exercise programs that promote
senior fitness.
26.	(1998) American College of Sports Medicine Position Stand. Exercise
and physical activity for older adults. Med Sci Sports Exerc 30(6): 992-
1008.
27.	Belardinelli R, Georgiou D, Cianci G, Purcaro A (1999) Randomized,
controlled trial of long-term moderate exercise training in chronic
heart failure: effects on functional capacity, quality of life, and clinical
outcome. Circulation 99(9): 1173-1182.
28.	John Hopkins Medicine (2013) Mouse Research Links Adolescent stress
and severe adult mental illness.
29.	Luo Y, Hawkley, Waite LJ, Cacioppo JT (2012) Loneliness, health and
mortality in old age: a national longitudinal study. Soc Sci Med 74(6):
907-914.
30.	Partridge L, Mangel M (1999) Messages from mortality: the evolution of
death rates in the old. Trends Ecol Evol 14(11): 438-442.
31.	Umberson D, Montez JK (2010) Social relationships and health: a
flashpoint for health policy. J Health Soc Behav 51(Suppl): S54-S66.
32.	University of Texas Health County Psychiatric Centre (2008).
Schizophrenia.

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Social Isolation in the Elderly; Physical Activity to the Rescue -Crimson Publishers

  • 1. 1/3 Introduction Social isolation refers to “a state in which an individual lacks a sense of belonging socially, lacks engagement with others, has a minimal number of social contacts and they are deficient in fulfilling quality relationships” [1]. It could be seen either as a potential cause or symptom of an emotional/psychological disorder (John Hopkins University, 2013; University of Texas Health County Psychiatric Centre, 2008). Social relationships are integral to the human well- being and are critically involved in the maintenance of health [2]. Social network and support among other factors affect the quality of life of elderly people [3]. Numerous studies have shown that people who have satisfying relationships with family, friends and their community are happier, have less health challenges and live longer. On the contrary, a relative lack of social connections has been linked with depression and later-life cognitive decline [4]. In 1988, House, Landis and Umberson found that social relationships had as much impact on physical health as blood pressure, smoking, physical activity and obesity, therefore, the effects of social network size on health are robust. Broadly speaking, there are three distinct ways through which social ties work to influence health: behavioural, psychological and physiological [5]. Human beings are naturally sociable; feeling isolated can often have a negative impact on our health holistically. Therefore, keeping in touch with friends and families can be beneficial for our well-being. The negative impact of social isolation Social isolation is often discussed in conjunction with loneliness as both concepts are often used synonymously in everyday language although they tend to be different in some respects. Similar to loneliness, social isolation is multidimensional because it encompasses physical, mental-health, psychological, and social dimensions [6]. The health implications of social isolation are well documented in relevant literatures; for instance, a meta-analysis carried out by Holt-Lunstad, Smith & Layton involving one hundred and forty eight (148) studies, between 1900 and 2007 revealed that elderly individuals who have unsatisfactory or limited social relationships have an increased mortality risk than people with stronger social networks. It was also found that loneliness and social isolation are associated with an increased risk of developing coronary heart disease and stroke [7]. Other adverse effects that could result from social isolation include increased blood pressure, abnormal stress response, heart disease and poor sleep [8]. Social isolation has been directly linked to aging, in recognition that growing older presents increased risks of ending up alone through death of a spouse [9]. The aging process involves the progressive functional decline, or a gradual deterioration of physiological function with age, including a decrease in fecundity [10]. It represents the closing period in one’s lifespan when an individual reflects on his/her life and begins to finish off his life course [11]. This inevitable stage in a man’s life is undoubtedly associated with a spectrum of physiological changes that not only limit our normal functions but render us more susceptible to diseases and ultimately death. One of the psychological/social issues possible as one ages is decreased social contact which may ultimately lead to social isolation. This affects the health Ogundiran Opeyemi Olufemi* Department of Physiotherapy, Obafemi Awolowo University Teaching Hospital, Nigeria *Corresponding author: Ogundiran Opeyemi Olufemi, Department of Physiotherapy, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun State, Nigeria, Tel: +234807083440031; Email: Submission: December 06, 2017; Published: December 18, 2017 Social Isolation in the Elderly; Physical Activity to the Rescue Opinion Degenerative Intellect Dev Disabil Copyright © All rights are reserved by Ogundiran Opeyemi Olufemi. CRIMSONpublishers http://www.crimsonpublishers.com Abstract Human beings are naturally sociable, and this evidence can be seen in the establishment of many types of relationships among them. There are endless benefits associated with social interactions which are critical to the maintenance of optimal health. A socially-isolated individual usually lacks a sense of belonging among his or her peers which could inevitably lead to depression or its associated symptoms especially in the geriatric population. The problem of social isolation among older adults is emerging due to several risk factors. The major aim of this opinion article is to critically examine the relevance of physical activity in tackling social isolation among the elderly. Keywords: Elderly; Social isolation; Social interactions
  • 2. How to cite this article: Ogundiran O O. Social Isolation in the Elderly; Physical Activity to the Rescue. Dev Disabil: 1(1): DIDD.000502. 2017. Degenerative Intellectual & Developmental Disabilities 2/3 Degenerative Intellect Dev Disabil and behavioural habits of elderly persons. For instance, an older person’s social network can impact his or her health positively through encouragement to adhere to a medical treatment or to abstain from negative and risky behaviours [12]. Increased social engagement as measured by the frequency of late-life social activities in older individuals is associated with longevity and a decreased risk of dementia, while being lonely has been linked with disability and an accelerated rate of motor decline [13]. In fact, older people who are lonely tend to experience decline in their mobility than those who are not and are also likely to die sooner [14]. Loneliness is a growing problem in older adults and risk factors such as lack of access to private transport, minimal or no contact with friends and family, low morale and living alone have made elderlyindividualsvulnerabletoit[15].Thereisastrongcorrelation with malnutrition, repeated hospitalization, cognitive regression and grave alcoholic problem [16]. In Nigeria, urbanization and changes to the family structure are being touted as factors leading to social isolation of the elderly [17]. The population of older adults is increasing rapidly with people with aged sixty and older currently making up 12.3 per cent of the global population. It is estimated that the number will rise to almost 22 per cent by the year 2050 [18]. With this in mind, social isolation will likely impact the health, well-being, and quality of life of numerous elderly persons now and in the foreseeable future. The value of elderly persons to the society cannot be overemphasized especially in conflict resolutions within families and communities, care giving, volunteering, and passing of cultural traditions to younger generations. Consequently, in developed societies such as the US and UK, many government policies, programmes and interventions are already being geared towards limiting the vulnerability of these senior citizens to inevitable developments associated with ageing. Tackling social isolation through research Several studies have been carried out in order to address the problem of social isolation with some explicitly targeting lonely elderly individuals while others did not focus on them. A systematic reviewdonebyDickens,Richards,Greaves&Campbell[19]involving thirty two (32) studies (16 randomized controlled trials and 16 quasi-experimentalstudies)focusedontheeffectivenessofdifferent “social” interventions for alleviating social isolation in older people. It was however concluded from this review that additional quality research studies on the effectiveness of these social interventions are required in order to improve the evidence base. According to another review by Cohen-Mansfield & Perach [20] involving thirty four (34) studies examining the utility of loneliness interventions among older persons, it was suggested that it is possible to reduce social isolation by using educational interventions focused on social networks maintenance and enhancement. A recent systematic review by Robins, Jansons & Haines [21] investigated the impact of physical activity interventions on social isolation among community-dwelling older adults. A methodologically inclusive review of existing literature yielded a total of seventeen (17) studies due to the dearth of randomized controlled trials examining the effect of physical activity interventions on social isolation of elderly people. The results of this review suggested that group physical activity interventions are associated with decreases in social isolation among community-dwelling older adults. In adults aged 65 years and above, physical activity includes leisure time activities such as walking, dancing, gardening, hiking, swimming, household chores, games, sports, or planned exercise [22]. Increasing physical activity levels is one of the most efficacious interventions to improve health in populations [23], psychosocial health inclusive. Many activity/exercise programs have been designed for elderly persons in a bid to reduce isolation and its consequences [24]. Examples of these programs are: active choices, active living every day, enhance fitness, enhance wellness, fit and strong, healthy moves for ageing, and walk with ease [25]. These programs are low cost initiatives and have been implemented in existing community and senior centres; they have also been found to be sustainable and replicable in many urban and rural communities. Discussion/Conclusion Asinthecaseofyoungeradults,regularexercisehasbeenshown to provide myriad of benefits in elderly persons with evidence- base improvements in cardiovascular, metabolic, endocrine and psychological (which is the most relevant in this article) health [26-30]. These physical activities/exercises shouldn’t be strenuous because of comorbidities associated with advanced age however, encouraging elderly persons to remain active in their hobbies and interests remains one of the most viable ways of nullifying the negative effects of loneliness. Tackling social isolation among our ageing population is a great challenge we cannot underestimate, both at individual and community levels, therefore, physical activity specifically regular exercise is a promising, non-pharmaceutical intervention to prevent and manage loneliness and other age- related diseases in our senior citizens [31,32]. References 1. Nicholson N (2009) Social isolation in older adults: an evolutionary concept analysis. J Adv Nurs 65(6): 1342-1352. 2. Holt-Lunstad J, Smith TB, Layton JB (2010) Social relationships and mortality risk: A meta-analysis review. PLOS Med 7(7): e1000316. 3. Everard KM, Lach HW, Fisher EB, Baum MC (2000) Relationship of activity and social support to the functional health of older adults. J Gerontol B psychol Sci Soc Sci 55(4): S208-S212. 4. Harvard Medical School (2010) The health benefits of strong relationship. Harvard Health Publications, USA. 5. House JS, Landis KR, Umberson D (1988) Social relationships and Health. Science 241(4865): 540-545. 6. Keefe J, Andrew M, Fancey P, Hall M (2006) Final report: A profile of social isolation in Canada, pp. 1-42. 7. Valtorta N, Kanaan M, Gilbody S, Hanratty B (2016) Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies. Heart, pp. 308790.
  • 3. How to cite this article: Ogundiran O O. Social Isolation in the Elderly; Physical Activity to the Rescue. Dev Disabil: 1(1): DIDD.000502. 2017. 3/3 Degenerative Intellect Dev DisabilDegenerative Intellectual & Developmental Disabilities 8. Luanaigh CO, Lawlor BA (2008) Loneliness and the health of older people. Int J Geriatr Psychiatry 23(12): 1213-21. 9. Edelbrock D, Buys L, Waite L, Grayson D, Broe A, et al. (2001) Characteristics of social support in a community-living sample of older people: The Sydney Older Persons Study. Australasian Journal on Ageing 20(4): 173-178. 10. Lopez-Otin C, Blasco M, Partridge L, Serrano M, Kroemer G (2013) The hallmarks of aging. Cell 153(6): 1194-1217. 11. Warnick J (1995) Listening with different ears: counselling people over sixty. QED Press, Ft Bragg, CA USA. 12. BerkmanL,GlassT,BrissetteI,SeemanTE(2000)Fromsocialintegration to health: Durkeim in the new millennium. Soc Sci Med 51(6): 843-857. 13. Fratiglioni L, Paillard-Borg S, Winblad B (2004) An active and socially integrated Lifestyle in late life might protect against dementia. Lancet Neurol 3(6): 343-53. 14. Perissinotto CM, Stijacic CI, Covinsky KE (2012) Loneliness in older persons: a predictor of functional decline and death. Arch Intern Med 172(14): 1078-1083. 15. Victor C, Schambler S, Bond J, Bowling A (2000) Being alone in later life: Loneliness, isolation and living alone in later life. Reviews in clinical Gerontology 10(4): 407-410. 16. Cacioppo JT, Hawkley LC (2009) Perceived social isolation and cognition. Trends Cogni Sci (10): 447-454. 17. Gureje O, Kola L, Afolabi E, Olley B (2010) Determinants of quality of life of elderly Nigerians: results from the Ibadan study of ageing. Afr J Med Med Sci 37(3): 239-247. 18. United Nations Population Fund (2015) Ageing. 19. Dickens AP, Richards SH, Greaves CJ, Campbell JL (2011) Interventions targeting social isolation in older people: a systematic review. BMC Public Health 15: 11-647. 20. Cohen-Mansfield J, Perach R (2015) Interventions for alleviating loneliness among older persons: a critical review. Am J Health Promot 29(3): e109-125. 21. Robins L, Jansons P, Haines T (2016) The impact of physical activity interventions on social interventions on social isolation among community-dwelling older adults: a systematic review. Research & Reviews: Journal of Nursing and Health Science 2(1): 62-71. 22. World Health Organization (2016) WHO Physical activity and older adults. 23. Paterson DH, Jones GR, Rice CL (2007) Aging and physical activity: evidence to develop exercise recommendations for older adults. Can J Public Health 98(Suppl 2): S69-108. 24. Coyle C, Dugan E (2012) Social isolation, loneliness and health among older adults. J Aging Health 24(8): 1346-1363. 25. National Council on Aging (2016) Exercise programs that promote senior fitness. 26. (1998) American College of Sports Medicine Position Stand. Exercise and physical activity for older adults. Med Sci Sports Exerc 30(6): 992- 1008. 27. Belardinelli R, Georgiou D, Cianci G, Purcaro A (1999) Randomized, controlled trial of long-term moderate exercise training in chronic heart failure: effects on functional capacity, quality of life, and clinical outcome. Circulation 99(9): 1173-1182. 28. John Hopkins Medicine (2013) Mouse Research Links Adolescent stress and severe adult mental illness. 29. Luo Y, Hawkley, Waite LJ, Cacioppo JT (2012) Loneliness, health and mortality in old age: a national longitudinal study. Soc Sci Med 74(6): 907-914. 30. Partridge L, Mangel M (1999) Messages from mortality: the evolution of death rates in the old. Trends Ecol Evol 14(11): 438-442. 31. Umberson D, Montez JK (2010) Social relationships and health: a flashpoint for health policy. J Health Soc Behav 51(Suppl): S54-S66. 32. University of Texas Health County Psychiatric Centre (2008). Schizophrenia.