Smart solution for monitoring Glaucoma using smartphone and pressure sensor embedded contact lens: *People with diabetes are twice as likely to develop glaucoma as are non-diabetics * Around 8% (366 million) of world population is suffering from type 2 diabetes *Increased IOP is at higher risk of Glaucoma *There are typically no early warning signs or symptoms of open-angle glaucoma. It develops slowly and sometimes without noticeable sight loss for many years.

1. Jaipal D
Version v0.1
April 28, 2014
Smart Glaucoma Meter

2. CONFIDENTIAL 5/15/2014, v0.1
Contents
• Problem Statement
• The Idea
• Existing Solutions
• References
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3. CONFIDENTIAL 5/15/2014, v0.1
Problem Statement
• Glaucoma is the second most common cause
of blindness around the world, and is an
irreversible progressive disease of the optic
nerve that can eventually lead to blindness
• Although there is no cure for the damaged
optical nerve due to increased intraocular
pressure (IOP) over time, its progress can be
controlled if diagnosed early and treated
properly
• The standard test is the measurement of IOP,
using an instrument known as tonometer
measured by an ophthalmologist in the clinic
• Increased IOP is usually non-symptomatic,
thus the first symptom of Glaucoma can be
reduced/loss of vision
• People with diabetes are twice as likely to
develop glaucoma as are non-diabetics
• Around 8% (366 million) of world population is
suffering from type 2 diabetes
• People at risk for Glaucoma need frequent
monitoring of IOP
• Current solutions (conventional tonometry)
requires frequent visit to ophthalmologists,
costing money, time and inconvenience
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4. CONFIDENTIAL 5/15/2014, v0.1
The Idea
• Strain gauge (MEMS) combined with NFC chip, embedded
in the silicone soft contact lens, can pick up the corneal
curvature variations, due to IOP variations in the eye, and
transfer it to NFC enabled smartphone for further
processing and Glaucoma assessment
• The Glaucoma meter contact lens is a passive device and
powered wirelessly by a smartphone NFC active device for
IOP measurements
• The Glaucoma meter contact lens is easy to wear like any
other contact lens and can be of multiple use
• Depending on the cost of the contact lens, the cost of
Glaucoma testing is far less and convenient than the
conventional way of testing
• People at risk for Glaucoma can self monitor IOP at ease
without any visits to clinics
• Simple application on the smart phone can process the data
from the contact lens without any additional hardware
• Components
– Soft contact lens embedding gauge sensor (MEMS)
and NFC chip, smartphone (NFC enabled) running
Glaucoma meter application
• Users
– Glaucoma risk patients, Field medical professionals,
etc.
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5. CONFIDENTIAL 5/15/2014, v0.1
Existing Solutions
• Existing solution, Triggerfish from Sensimed AG,
Switzerland, is targeted at continuous (24Hrs)
monitoring of IOP
• Requires patients to be hospitalized, requires visits
to clinics for Glaucoma assessment, expensive
solution
• Components
– Sensor
• Soft, hydrophilic silicone disposable contact
lens embedding a MEMS sensor and a
telemetry microprocessor
– Antenna and data cable
• A circular antenna taped around the eye which
sends energy to the sensor and receives the
measurement information
– Recorder
• A battery powered recorder which will store
measurement information and wirelessly upload
this information on the ophthalmologist’s
computer at the end of the monitoring session
– Software
• The software running on the ophthalmologist’s
computer to retrieve and to visualize the
intraocular pressure profile
• Conventional ocular tonometry
– e.g. Goldmann tonometry
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6. CONFIDENTIAL 5/15/2014, v0.1
References
1. First Steps toward Noninvasive Intraocular Pressure Monitoring with a
Sensing Contact Lens
– Matteo Leonardi, Peter Leuenberger, Daniel Bertrand, Arnaud Bertsch, and
Philippe Renaud
– IOVS, September 2004, Vol. 45, No. 9
2. Tiggerfish Glaucoma Monitoring System
– Sam Karnes, Biomedical Engineering, University of Rhode Island
– BME 181 First Presentation, March 4, 2013
3. Continuous 24-Hour Monitoring of Intraocular Pressure Patterns With
a Contact Lens Sensor: Safety, Tolerability, and Reproducibility in
Patients With Glaucoma
– Kaweh Mansouri, MD, MPH; Felipe A. Medeiros, MD, PhD; Ali Tafreshi, BS;
Robert N. Weinreb, MD
– ARCH OPHTHALMOL/VOL 130 (NO. 12), DEC 2012
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7. CONFIDENTIAL 5/15/2014, v0.1 7
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