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INTRAOCULAR PRESSURE
AND
TONOMETRY
Dr. Zaw Min Htet
Ophthalmologist
EENT Hospital
Intraocular Pressure
• The fluid pressure inside the eye.
• Normal - 11-21 mmHg
Factors influencing IOP
Long Term Variation
• Age -increase with Age
• BP - increase with BP
• BMI - increase with BMI
• Climate - increase in winter
Short Term Fluctuations
• Alcohol consumption - a transient decrease in IOP
• Cannabis - decreases IOP
• IOP is higher in recumbent rather than upright position, predominantly
because of an increase in the episcleral venous pressure
• Caffeine - Increase IOP
Factors influencing IOP
Diurnal Variations
• Increase in morning
• Normal variation = 4 mmHg (> 10 mmHg in glaucoma)
• Accentuated in POAG
Eye Movement
• Clinically important in restrictive ophthalmopathy (e.g. thyroid eye
disease, pseudotumor)
Exercise
• Decrease in IOP
• Correlated to metabolic acidosis and changes in extracellular fluid
volume and osmolality
Factors influencing IOP
Pharmacological Effects
1. succinylcholine (muscle relaxant ) used in anaesthesia -transient increase IOP (by
around 10 mmHg for a few minutes)
2. Ketamine - increases IOP
TONOMETRY
Tonometry -The procedure to determine the IOP
Tonometer - a device to determine the IOP
APPLANATION
TONOMETRY
Goldmann applanation tonometry
GAT - Gold Standard
• based on the Imbert–Fick principle, for an ideal, dry, thin-
walled sphere, the pressure inside the sphere (P) equals the
force necessary to flatten its surface (F) divided by the area
of flattening (A)
• P = F/A
GAT
Type to enter a caption.
APPLANATION
TONOMETRY
• GAT - an accurate variable-force tonometer consisting of a double prism
• The tonometer prism should be disinfected between patients
• 2% sodium-hypochlorite (dilute bleach) - effective disinfection against
adenovirus and HSV
• disinfectants - cause the tonometer tip to swell and crack with time and lead
to disinfectant entering the tonometer tip resulting in a corneal abrasion
• 70% isopropyl alcohol wipes do not offer protection against viral infections
• Disposable tonometer prisms and caps have been introduced to address
concerns of infection from reusable prisms
Technique
• Topical anaesthetic (commonly proxymetacaine 0.5%) and a small amount of
fluorescein
• The patient is positioned at the slit lamp and instructed to look straight ahead
• With the cobalt blue filter and illumination of maximal intensity obliquely
(approximately 60°) at the prism, the prism is centred in front of the apex of the
cornea
• The dial is preset at 1 (i.e. 10 mmHg )
• The prism is advanced until it just touches the apex of the cornea
• 2 green semi-circular mires
• The dial on the tonometer is rotated to make the inner margins of the semi-circles
align
• The reading on the dial, multiplied by 10, gives the IOP in mmHg
GAT
SOURCE OF ERROR
1. Inappropriate fluorescein pattern
• Excessive fluorescein - too thick- overestimation of IOP
• Insufficient - the semi-circles too thin - underestimation of IOP
2. Pressure on the globe from the examiner’s fingers
• eyelid squeezing or restricted EOM (e.g. thyroid myo- pathy) - high reading
3. Central corneal thickness (CCT)
• GAT assume that CCT is 520 μm, with minimal normal variation
• If the cornea is thinner, an underestimation of IOP and if thicker, an
overestimation
• Conea - Thicker in OHT - Overestimation, Thinner in NTG and Refractive Surgery
(Underestimation)
SOURCE OF ERROR
4. Astigmatism if significant - distorted mires - mechanically induced errors.
5. Corneal Oedema - Artificial lowering of IOP
6. Incorrect calibration of the tonometer - a false reading
7. Wide pulse pressure
8. Repeated readings over a short period - a slight fall in IOP due to a
massaging effect on the eye.
9. Other factors - a tight collar and breath-holding - obstruct venous return- raise
IOP
APPLANATION
TONOMETRY
Pneumotonometry
• based on the principle of applanation, but the central part of the cornea is
flattened by a jet of air rather than a prism
• The time required to sufficiently flatten the cornea relates directly to the
level of IOP
• No contact with the eye and No need topical anaesthesia
• particularly useful for screening in the community
• The sudden jet of air can startle the patient
• Accuracy is improved if an average of at least three readings is taken
Pneumotonometer
Keeler Portable
Pneumotonometer
APPLANATION TONOMETRY
Portable applanation tonometry (Perkins)
• a Goldmann prism in conjunction with a portable light source
• hand-held and used in bed-bound or anaesthetized patients
Electronic indentation/applanation
Tonometry (e.g. Tono- Pen® )
• a hand-held electronic contact tonometer (a modified version
of the older Mackay–Marg tonometer)
• The probe tip contains a transducer that measures applied
force
• Besides portability, main advantage - the facility to measure
IOP reasonably accurately in eyes with distorted or
oedematous corneas and through a soft contact lens
TONO-PEN
DYNAMIC CONTOUR
TONOMETRY
Dynamic contour tonometry (DCT) (e.g. PASCAL®)
• a solid-state sensor and a corneal contour-matching surface
(instead of applanation) with the aim of measuring IOP relatively
independently of corneal mechanical factors such as rigidity
• mounted on a slit lamp like GAT and IOP shown on a digital
display
• Studies comparing DCT and GAT IOP readings with manometric
intracameral IOP seem to confirm DCT as providing a more
physiological measurement
PASCAL
Rebound Tonometry
Rebound tonometry (e.g. iCare®)
• Hand-held and portable
• involves a 1.8 mm plastic ball attached to a wire
• Deceleration of the probe upon contact with the cornea is proportional to IOP
• Anaesthesia is not required
• Especially in children
• used for self-monitoring – a tailored personal version is available – and for
screening in the community
I Care Tonometer
I Care 100ic I Care Home
I Care 100ic
Indentation Tonometry
Indentation (impression) tonometry (e.g. Schiotz)
• a seldom-used portable device that measures the extent
of corneal indentation by a plunger of known weight
Ocular Response Analyser
Ocular response analyser (e.g. Reichert®)
• utilizes air-puff technology to record two applanation
measurements:
• one while the cornea is moving inward and one when
the cornea returns to its normal position.
• The average of these two IOP measurements provides
a Goldmann-correlated IOP measurement.
Ocular Response Analyser
THE END

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INTRAOCULAR PRESSURE &TONOMETRY Dr. ZAW MIN HTET (OPHTHALMOLOGIST)

  • 1. INTRAOCULAR PRESSURE AND TONOMETRY Dr. Zaw Min Htet Ophthalmologist EENT Hospital
  • 2. Intraocular Pressure • The fluid pressure inside the eye. • Normal - 11-21 mmHg
  • 3. Factors influencing IOP Long Term Variation • Age -increase with Age • BP - increase with BP • BMI - increase with BMI • Climate - increase in winter Short Term Fluctuations • Alcohol consumption - a transient decrease in IOP • Cannabis - decreases IOP • IOP is higher in recumbent rather than upright position, predominantly because of an increase in the episcleral venous pressure • Caffeine - Increase IOP
  • 4. Factors influencing IOP Diurnal Variations • Increase in morning • Normal variation = 4 mmHg (> 10 mmHg in glaucoma) • Accentuated in POAG Eye Movement • Clinically important in restrictive ophthalmopathy (e.g. thyroid eye disease, pseudotumor) Exercise • Decrease in IOP • Correlated to metabolic acidosis and changes in extracellular fluid volume and osmolality
  • 5. Factors influencing IOP Pharmacological Effects 1. succinylcholine (muscle relaxant ) used in anaesthesia -transient increase IOP (by around 10 mmHg for a few minutes) 2. Ketamine - increases IOP
  • 6. TONOMETRY Tonometry -The procedure to determine the IOP Tonometer - a device to determine the IOP
  • 7. APPLANATION TONOMETRY Goldmann applanation tonometry GAT - Gold Standard • based on the Imbert–Fick principle, for an ideal, dry, thin- walled sphere, the pressure inside the sphere (P) equals the force necessary to flatten its surface (F) divided by the area of flattening (A) • P = F/A
  • 8. GAT Type to enter a caption.
  • 9.
  • 10. APPLANATION TONOMETRY • GAT - an accurate variable-force tonometer consisting of a double prism • The tonometer prism should be disinfected between patients • 2% sodium-hypochlorite (dilute bleach) - effective disinfection against adenovirus and HSV • disinfectants - cause the tonometer tip to swell and crack with time and lead to disinfectant entering the tonometer tip resulting in a corneal abrasion • 70% isopropyl alcohol wipes do not offer protection against viral infections • Disposable tonometer prisms and caps have been introduced to address concerns of infection from reusable prisms
  • 11. Technique • Topical anaesthetic (commonly proxymetacaine 0.5%) and a small amount of fluorescein • The patient is positioned at the slit lamp and instructed to look straight ahead • With the cobalt blue filter and illumination of maximal intensity obliquely (approximately 60°) at the prism, the prism is centred in front of the apex of the cornea • The dial is preset at 1 (i.e. 10 mmHg ) • The prism is advanced until it just touches the apex of the cornea • 2 green semi-circular mires • The dial on the tonometer is rotated to make the inner margins of the semi-circles align • The reading on the dial, multiplied by 10, gives the IOP in mmHg
  • 12. GAT
  • 13. SOURCE OF ERROR 1. Inappropriate fluorescein pattern • Excessive fluorescein - too thick- overestimation of IOP • Insufficient - the semi-circles too thin - underestimation of IOP 2. Pressure on the globe from the examiner’s fingers • eyelid squeezing or restricted EOM (e.g. thyroid myo- pathy) - high reading 3. Central corneal thickness (CCT) • GAT assume that CCT is 520 μm, with minimal normal variation • If the cornea is thinner, an underestimation of IOP and if thicker, an overestimation • Conea - Thicker in OHT - Overestimation, Thinner in NTG and Refractive Surgery (Underestimation)
  • 14. SOURCE OF ERROR 4. Astigmatism if significant - distorted mires - mechanically induced errors. 5. Corneal Oedema - Artificial lowering of IOP 6. Incorrect calibration of the tonometer - a false reading 7. Wide pulse pressure 8. Repeated readings over a short period - a slight fall in IOP due to a massaging effect on the eye. 9. Other factors - a tight collar and breath-holding - obstruct venous return- raise IOP
  • 15. APPLANATION TONOMETRY Pneumotonometry • based on the principle of applanation, but the central part of the cornea is flattened by a jet of air rather than a prism • The time required to sufficiently flatten the cornea relates directly to the level of IOP • No contact with the eye and No need topical anaesthesia • particularly useful for screening in the community • The sudden jet of air can startle the patient • Accuracy is improved if an average of at least three readings is taken
  • 17. APPLANATION TONOMETRY Portable applanation tonometry (Perkins) • a Goldmann prism in conjunction with a portable light source • hand-held and used in bed-bound or anaesthetized patients
  • 18. Electronic indentation/applanation Tonometry (e.g. Tono- Pen® ) • a hand-held electronic contact tonometer (a modified version of the older Mackay–Marg tonometer) • The probe tip contains a transducer that measures applied force • Besides portability, main advantage - the facility to measure IOP reasonably accurately in eyes with distorted or oedematous corneas and through a soft contact lens
  • 20. DYNAMIC CONTOUR TONOMETRY Dynamic contour tonometry (DCT) (e.g. PASCAL®) • a solid-state sensor and a corneal contour-matching surface (instead of applanation) with the aim of measuring IOP relatively independently of corneal mechanical factors such as rigidity • mounted on a slit lamp like GAT and IOP shown on a digital display • Studies comparing DCT and GAT IOP readings with manometric intracameral IOP seem to confirm DCT as providing a more physiological measurement
  • 22. Rebound Tonometry Rebound tonometry (e.g. iCare®) • Hand-held and portable • involves a 1.8 mm plastic ball attached to a wire • Deceleration of the probe upon contact with the cornea is proportional to IOP • Anaesthesia is not required • Especially in children • used for self-monitoring – a tailored personal version is available – and for screening in the community
  • 23. I Care Tonometer I Care 100ic I Care Home I Care 100ic
  • 24. Indentation Tonometry Indentation (impression) tonometry (e.g. Schiotz) • a seldom-used portable device that measures the extent of corneal indentation by a plunger of known weight
  • 25. Ocular Response Analyser Ocular response analyser (e.g. Reichert®) • utilizes air-puff technology to record two applanation measurements: • one while the cornea is moving inward and one when the cornea returns to its normal position. • The average of these two IOP measurements provides a Goldmann-correlated IOP measurement.