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This document discusses the relationship between obesity, cholesterol, triglycerides, and metabolic syndrome. It notes that adipose tissue plays a key role in inflammation and the development of cardiometabolic risk factors. Accumulation of macrophages in adipose tissue promotes inflammation linked to conditions like insulin resistance, dyslipidemia, and atherosclerosis. While removing abdominal fat does not improve risks, reducing visceral fat does help glucose and insulin sensitivity. The document also outlines assessments, lifestyle interventions, nutraceuticals, exercise, and pharmaceutical treatments for metabolic syndrome.
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Post partum presentation
Postpartum mood disorders can range from mild baby blues to severe postpartum psychosis. Postpartum psychosis occurs in the first 1-4 weeks after delivery in 0.1-0.2% of births and is associated with hormone shifts. Screening tools like the Edinburgh Postnatal Depression Scale are used to assess levels of depression. Postpartum depression is diagnosed using DSM-IV criteria including 5 symptoms of depression emerging within 4 weeks of delivery. Left untreated, postpartum mood disorders can cause risks like suicide, infanticide, and cognitive impairment. Treatments include medications, psychotherapy, electroconvulsive therapy, and hospitalization.
NCM 105 Overview
The document provides an overview of the historical development of psychiatric care and mental health nursing. It describes the evolution from primitive beliefs that mental illness was caused by demonic possession to more humane treatment in asylums and the development of psychopharmacology in the 1950s. Key concepts discussed include Maslow's theory of mental health, the World Health Organization's definition of mental health as a state of well-being, and the Diagnostic and Statistical Manual of Mental Disorders which provides a standardized system for diagnosing mental illnesses.
Misophonia
Misophonia is a disorder characterized by negative reactions to certain sounds, such as eating noises. People with misophonia experience emotions like rage and anxiety when exposed to trigger sounds. It is believed to involve an abnormal connection between the auditory and limbic systems of the brain, causing those with misophonia to perceive sounds more intensely than others. While the exact causes are unknown, treatments may include noise-reducing headphones and cognitive behavioral therapy to help manage symptoms.
The obesity phenomenon
This powerpoint decribes the pathophysiology of obesity and list strategies to prevent its occurance.
Metabolic syndrome toufiqur rahman
Introduction, Integration of CM risk factors, Targeting obesity, Management of hypertension, Management of dyslipidemia, Antiplatelet therapy, Management of microalbuminuria, CB1 blockade
Organic Mental Disorders
1. The document discusses various organic mental disorders including delirium, dementia, organic amnestic syndrome, and other organic disorders.
2. Delirium is characterized by acute onset of confusion and disorientation caused by a medical condition. Dementia is a chronic disorder marked by cognitive decline. Organic amnestic syndrome specifically involves memory impairment from organic causes.
3. Causes, clinical features, and management approaches are described for each disorder with a focus on identifying and treating underlying medical conditions.
Acute Peripheral Neurologic disorder
The document discusses several acute peripheral neurologic disorders that can cause respiratory failure, including Guillain-Barré syndrome (GBS), Myasthenia Gravis (MG), Lambert-Eaton Myasthenic Syndrome (LEMS), and Botulism. It provides details on the pathogenesis, signs and symptoms, diagnostic criteria, treatment options, and prognosis for each condition. Neural control of breathing and various respiratory investigations that can aid in diagnosis are also outlined.
Resiko metabolik
This document discusses cardiometabolic risk, which refers to the risks associated with metabolic changes that can lead to cardiovascular disease. It defines cardiometabolic risk and identifies both non-modifiable and modifiable risk factors such as obesity, dyslipidemia, hypertension, smoking, and physical inactivity. The document emphasizes the importance of early identification and management of risk factors through comprehensive patient assessment and targeted intervention to prevent diseases like cardiovascular disease and diabetes.
Neurobiology of stress
1. The document discusses the neurobiology of stress, including how stress is defined and the physiological stress response pathways in the body. It describes the stress response as involving the nervous, neuroendocrine, and endocrine systems.
2. Key parts of the stress response include the activation of the sympathetic nervous system and HPA axis, resulting in the "fight or flight" response. Prolonged stress can impact various organ systems in the body as target organs.
3. Coping strategies are discussed as ways to potentially attenuate the stress response and reestablish homeostasis, with adaptive coping being more beneficial than maladaptive coping.
Acid base imbalance in medicine
This document summarizes acid-base balance and disorders. It defines pH, acids, and bases. It explains the Henderson-Hasselbalch equation and how the body controls pH through buffers, respiration, and the kidneys. Common acid-base imbalances like respiratory acidosis, respiratory alkalosis, and metabolic acidosis are described along with their causes, signs, compensation mechanisms, and treatments. Key concepts are presented concisely with illustrative equations, tables, and diagrams.
1 Cardiovascular Disorders
The document provides an overview of cardiovascular disorders including diagnostic tests, treatment measures, specific conditions like coronary artery disease, myocardial infarction, cardiac arrhythmias, congestive heart failure, hypertension, and shock. It discusses the pathophysiology, signs and symptoms, diagnostic approach, and treatment options for each condition. Homework assignments involving case studies on specific topics are also outlined.
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This document summarizes a teleconference on diabetes and metabolic syndrome in patients hospitalized with cardiovascular disease. It discusses screening for diabetes and metabolic syndrome in hospitalized CVD patients, defines metabolic syndrome, reviews the prevalence and risk factors associated with it, and how metabolic syndrome predicts diabetes and increased cardiovascular risk. It also reviews inpatient management of hyperglycemia and metabolic syndrome.
Esteatose Framminghan
1) Fatty liver, measured using CT scans, was present in 17% of participants.
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This document summarizes a journal club discussion on the role of peroxisome proliferator-activated receptor gamma (PPARγ) agonists in treating diabetes and cardiovascular disease. PPARγ agonists like thiazolidinediones improve insulin resistance and reduce inflammation. They may protect blood vessels by inhibiting smooth muscle cell proliferation and migration involved in atherosclerosis and restenosis. While clinical trials show PPARγ agonists reduce cardiovascular risk factors, their side effects like fluid retention require monitoring, and further outcomes research is still needed to establish their long-term cardiovascular benefits and safety.
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This document discusses obesity and its relationship to heart disease. It defines obesity and describes how both genetic and behavioral factors contribute to being overweight. Visceral abdominal fat is associated with insulin resistance and metabolic syndrome, increasing risks for type 2 diabetes, hypertension, and cardiovascular disease. Obesity causes heart disease through mechanisms like insulin resistance, inflammation, and increased stress on the heart from carrying excess weight. Modest weight loss through diet and exercise can significantly reduce cardiovascular risks. Anti-obesity medications and bariatric surgery are treatment options for severe obesity when more conservative measures have failed.
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The document discusses macrovascular complications in diabetes. It notes that atherosclerosis is an inflammatory disease and lists some theories of atherogenesis. It also discusses C-peptide and its potential role in atherosclerosis. Finally, it provides definitions of the metabolic syndrome from various organizations like WHO, ATP III, and IDF and notes unresolved questions regarding the metabolic syndrome.
The Role of Adiponectin in Obesity and its Clinical Utility in Obesity-Associ...
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The document discusses non-alcoholic fatty liver disease (NAFLD) and its relationship to metabolic syndrome. It begins by defining NAFLD and its subtypes, including simple steatosis and non-alcoholic steatohepatitis (NASH). It then discusses the risk factors and pathophysiology of NAFLD, noting its association with obesity, diabetes, and other components of metabolic syndrome. The document outlines current diagnostic and treatment approaches for NAFLD, including lifestyle modifications involving diet, exercise and weight loss. It also discusses potential drug therapies and newer treatment strategies being explored.
Diabetic Dyslipidemia - A True CV risk
Diabetic Dyslipidemia
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ISMA CME Activity 2021
In Tolip EL Galala Hotel
-----------
Introduction
Physiology of lipid metabolism
Pathophysiology of diabetic dyslipidemia
Statin therapy (+/- ezetimibe) evidence and translation of evidence
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B0430913
This study evaluated the impact of diabetes mellitus and obesity on male infertility in Iraqi patients. It found that:
1) Serum levels of HbA1C, a marker of long-term blood sugar control, were higher in diabetic patients regardless of BMI compared to healthy controls. HbA1C was also higher in normo-BMI diabetic patients compared to obese diabetic patients.
2) Serum free testosterone levels, important for male fertility, were significantly lower in obese diabetic patients compared to overweight diabetic and healthy patients.
3) There was a significant negative correlation between serum free testosterone levels and HbA1C in obese diabetic patients, suggesting poorer blood sugar control is associated with lower testosterone.
Seaman, Palombo, Metabolic Syndrome, JCM 2014
This document provides an overview of a literature review on metabolic syndrome (MetS) and its identification and management in chiropractic practice. MetS is a cluster of risk factors that increases the risk of diseases like diabetes, heart disease, and stroke. It is estimated that 34% of US adults have MetS. Insulin resistance is a key component of MetS and is linked to inflammation. The literature review discusses the pathophysiology of MetS and insulin resistance, including the roles of visceral adiposity, hypothalamic inflammation, and diet-induced inflammation. MetS is associated with increased risk of diseases and also musculoskeletal complaints through inflammation and advanced glycation end products. The review suggests strategies for chiropractors
metabolic syndrome review
This document discusses metabolic syndrome, including its definition, causes, risk factors, prevalence in different populations, and treatment approaches. Metabolic syndrome is a cluster of conditions that increases the risk of cardiovascular disease and diabetes. It is characterized by abdominal obesity, high blood pressure, insulin resistance, and dyslipidemia. Lifestyle interventions like diet modification, increased physical activity, and weight loss are effective first-line treatments to reduce the risk factors of metabolic syndrome. The document reviews evidence on how different diets, exercises and weight management can help control metabolic syndrome.
Exercise and health
Exercise is any bodily activity that enhances or maintain physical fitness and overall health, Exercise with its Countless Benefits is the logical salvage for a group of diseases related to inactivity . In view of the prevalence, global reach and health effect of these physical inactivity related diseases, the issue should be appropriately described as pandemic, with far-reaching health, economic, social and Environmental consequences.These diseases include, Obesity, Coronary artery disease, Diabetes, Hypertension, Cancer, Depression and anxiety, Arthritis, Osteoporosis, Etc, etc, etc… I think we have no option except doing regular exercises if we seriously searching for a salvage to escape the bad and serious consequences of these new life style diseases.
Biomarkers in diabetes
This document discusses biomarkers in diabetes, including:
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2. Liver enzymes like ALT and GGT, inflammatory markers like CRP and IL-6, and adipokines like adiponectin have been implicated in diabetes pathogenesis.
3. Simple risk scores combining basic measures like HbA1c and lipids can effectively predict diabetes, though more research is still needed on novel biomarkers.
METABOLIC SYNDROME.pptx
The document discusses metabolic syndrome (MetS), also known as syndrome X. MetS is defined as a constellation of interconnected factors that increase the risk of cardiovascular disease, diabetes, and mortality. It commonly includes central obesity, elevated blood pressure, high blood glucose, excess body fat around the waist. The pathophysiology involves chronic low-grade inflammation and insulin resistance linked to obesity, genetic susceptibility, and lifestyle factors. Treatment focuses on lifestyle modifications like weight loss, dietary changes, and physical activity as well as medications.
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Poloz_Obesity_CDDis_2015
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Biochemistry dept news letter july_12
This document provides information about the Biomed newsletter from Adichunchanagiri Institute of Medical Sciences. It includes the editorial board members and details about the second issue of Biomed from July 2012. The newsletter aims to keep pace with trends in biochemistry and provide valuable information to readers. It thanks the principal for support and encourages readers to provide suggestions. A picture shows members of the Department of Biochemistry.
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Simpson edited version
- 1. The Relationship of Obesity – Cholesterol – Triglycerides to Metabolic Syndrome: Assessment and Interventions Presented by Graham Simpson, MD Institute Physician, Cenegenics ® Medical Institute
- 6. Prevalence of CAD Risk Factors
- 7. Parallels
- 8. Relative Risk of CAD Mortality
- 10. Associations
- 13. Patient Overview AVERAGE MIN MAX Age 51.8 28 73 Married 139 total Children 2.4 0 15 Ht 70.8 60.4 78.8 Wt 212.7 134 344.5 % body fat 30.3 9.2 44.2 Densitometer none = 95 Penia = 83 Porosis = 20 Depression 8.3 0 32 QLI 6.6 0 22 Glucose 95.3 65 245 A1C 5.6 4.6 11.2 M Gluc 123.2 86 321 F Insulin 7.6 1 59 Uric Acid 6.6 1.6 11.8 Homo 9.9 3.8 20.5 CRP 3.0 0.1 37.8 Chol 197.5 109 331 TG 151.4 39 975 HDL 49.7 31 99 LDL 121.3 40 235 Total Test 428.6 29 966 Free Test 67.2 5.6 936 DHT 37.8 2 182 E2 23.7 1 158 IGF 159.8 66 315 PSA 1.2 0.1 5.3 DHEA 163.5 2.5 1210 TSH 2.42 0.7 12.66
- 18. Eukaryotes
- 19. Paleolithic Nutrition A Consideration of Its Nature and Current Implications S. Boyd Eaton, MD, and Melvin Konner, PhD NEJM 31Jan85 Vol 312 No.5
- 20. Ancestral vs. Modern Humans
- 26. Effects