Sickle Cell Anemia is a genetic disorder caused by irregularly shaped red blood cells that are fragile and can block blood vessels, damaging organs and tissues and causing pain. It is inherited as a recessive trait, requiring both parents to carry the gene for a child to be affected. Symptoms include pain, fatigue, swelling, infections, and organ damage. While there is no cure, treatment focuses on pain management and preventing further cell clumping through therapies to keep blood flowing.