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Seritonin syndrome
Serotonin syndrome is a potentially life-threatening adverse drug reaction that results from excess serotonin activity in the central nervous system. It most commonly occurs when two or more serotonergic drugs are taken together, such as a combination of antidepressants. Symptoms range from tremors and diarrhea in mild cases to delirium, muscle rigidity, and hyperthermia in more severe cases. Treatment involves discontinuing the precipitating drugs, providing supportive care, and administering drugs that block serotonin receptors like cyproheptadine to counteract excess serotonin activity. Prevention relies on awareness of potential drug interactions and avoiding unnecessary combinations of serotonergic medications.
