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AN APPLICATION OF INTERVAL-
   VALUED FUZZY SOFT SETS IN

          MEDICAL DIAGNOSIS



Guide:Dr. Sunil Jacob John   Jobish VD
                             M090054MA
Contents.


1.   Preliminaries.
2.   Application of interval valued fuzzy
     soft set in medical diagnosis.
3.   Algorithm.
4.   Case Study.
1. Preliminaries.
 Definition  1.1[3]:
 Let U - initial universe set
     E - set of parameters.
     P (U) - power set of U.          and,
     A - non-empty subset of E.
     A pair (F, A) is called a soft set over U,
     where F is a mapping given by F: A P (U).
 Example   1.1;

Let U={c1,c2,c3} - set of three cars.
    E ={costly(e1), metallic color (e2), cheap (e3)}
                               - set of parameters.
      A={e1,e2} ⊂ E. Then;

(F,A)={F(e1)={c1,c2,c3},F(e2)={c1,c3}}

“ attractiveness of the cars” which Mr. X is going
  to buy .
 Definition 1.2[3]:
 Let U - universal set,
    E - set of parameters and A ⊂ E.
 Let F (U) - set of all fuzzy subsets of U.

Then a pair (F,A) is called fuzzy soft set over
 U, where F :A        F (U).
 Example  1.2;
 Let U = {c1,c2,c3} - set of three cars.
     E ={costly(e1),metallic color(e2) , getup (e3)}
                                  - set of parameters.
     A={e1,e2 } ⊂ E.

Then;
(G,A) = { G(e1)={c1/.6, c2/.4, c3/.3},
            G(e2)={c1/.5, c2/.7, c3/.8} }.
                        - fuzzy soft set over U.
 Describes the “ attractiveness of the cars” which
  Mr. S want.
.

     Definition 1.3[3]: An interval-valued fuzzy
     sets      X on the universe U is a mapping
     such that;
               X : U → Int ([0,1]).
     where; Int ([0,1])   - all closed sub-intervals
     of [0,1].

    The set of all interval-valued fuzzy sets on U is
     denoted by F (U).
 If,
ˆ            ~
X            F (U ), x U
                             L                  U
    x ( x)
    ˆ      [                     ˆ
                                 x   ( x),          ˆ
                                                    x   ( x)]   T hedegree of membership-
                                                                of an element xto X

    L
        ˆ
        x   ( x)         lower degree of membership x toX
    U
        ˆ
        x   ( x)             upper degree of membership x toX

              L                        U
0                 ˆ
                  x   ( x)                 ˆ
                                           x   ( x) 1.
ˆ ˆ            ~
   Let X , Y          F ( U ). Then,
    Union            ˆ         ˆ
                  of X and Y , denoted       by,
                        ˆ
                        X  Y     ˆ   is given by -
               ( x ) sup [             ( x) ,       ( x )]
      X  Yˆ
      ˆ
                               ˆ
                               x                ˆ
                                                y
                                   L                    L
                     [ sup (                ( x),                ( x)),
                                        ˆ
                                        x                    ˆ
                                                             y
                                                U                  U
                                   sup (                ( x),          ˆ
                                                                       y ( x ) ) ].
                                                    ˆ
                                                    x
       ˆ ˆ         ~
    Let X , Y      F ( U ). Then,
                       ˆ        ˆ
    Intersecti on of X and Y , denoted      by,
                     ˆ
                     X  Y    ˆ   is given by -

                ( x ) inf [       ( x) ,       ( x)]
       X  Yˆ
       ˆ
                              ˆ
                              x            ˆ
                                           y
                      [ inf ( L ( x),           L          ( x)),
                               ˆ
                               x                       ˆ
                                                       y
                                  inf ( U ( x ) , U ( x ) ) ].
                                         xˆ        ˆ
                                                   y
           ˆ   ˆ      ~
    Let     X, Y       F ( U ). Then,
    comlement of       ˆ
                       X             denoted          ˆ c,
                                                   by X
                       and              is     given   by -

          (x)   1-          ( x) .
     ˆ
     Xc
                       ˆ
                       x
                [1 -       U ( x ) , 1 - L ( x ) ) ].
                            ˆ
                            x             ˆ
                                          y
 Definition   1.7 [4]:
Let U         universal set.
    E        set of parameters.
                    and A ⊂E.
 ~          set of all interval-valued fuzzy sets on
F (U )
                                                U.
Then a pair (F, A) is called interval-valued fuzzy
  soft set over U.
                           ~
       where F : A        F (U ).
 Definition  1.8[5]: The complement of a
 interval valued fuzzy soft set (F,A) is,

  (F,A)C = (FC,¬A),
       where ∀α ∈ A ,¬α = not α .

 FC: ¬A        F ( U ).

 FC(β ) = (F ( ¬β ))C , ∀β ∈ ¬A
 Example2.3:
  Let U={c1,c2,c3}     set of three cars.
     E ={costly(e1), grey color(e2),mileage (e3)},
                  set of parameters.
     A={e1,e2} ⊂ E. Then,

(G,A) = {
         G(e1)=〈c1,[.6,.9]〉,〈c2,[.4,.6]〉,〈c3,[.3,.5]〉,
         G(e2)= 〈c1,[.5,.7]〉, 〈c2,[.7,.9]〉 〈c3,[.6,.9]〉
            }
“ attractiveness of the cars” which Mr. X want.
 Example 2.4:
     In example 2.3,
(G,A)C = {
  G(¬e1)=〈c1,[0.1,0.4]〉,     〈c2,[0.4,0.6]〉,
           〈c3,[0.5,0.7]〉,
  G(¬e2)=〈c1,[0.3,0.5]〉,     〈c2,[0.1,0.3]〉
           〈c3,[0.1,0.4]〉
                  }.
2. Application –
             in
         medical diagnosis.
S   - Symptoms, D – Diseases, and P - Patients.
 Construct an I-V fuzzy soft set (F,D) over S
              ~
        F:D→ F ( S ).
 A relation matrix say, R1 - symptom-disease
  matrix- constructed from (F,D).
 Its complement (F,D)c gives          R2 - non
  symptom-disease matrix.
 We construct another I-V fuzzy soft set (F1,S)
                  ~
  over P, F1:S→ F ( P).
 We  construct another I-V fuzzy soft set (F1,S)
                 ~
  over P, F1:S→ F ( P).
 Relation matrix Q - patient-symptom matrix-
  from (F1,S).
Then matrices,
 T1=Q R1 - symptom-patient matrix, and
 T2= Q R2 - non symptom-patient matrix.
The membership values are calculated by,
               T1
                    ( pi , d k ) [a, b]
                       L                          L
a    inf {                 Q       ( pi , e j )       R1    (e j , d k , )},
          j

                                                      U
b   sup {                  U
                               Q   ( pi , e j )            R1   (e j , d k , )}
           j


               T2
                    ( pi , d k ) [ x, y ]
                       L                          L
x   inf {                  Q   ( pi , e j )           R2   (e j , d k , )},
      j

                                                  U
y   sup {              U
                               Q   ( pi , e j )        R2       (e j , d k , )}
       j
The membership values are calculated by,
        S T1 ( pi , d j )             p     q
                    L                           L
  p             {       T1   ( pi , d j )           T1   ( p j , d i )}
            j
                    U                           U
  q             {       T1   ( pi , d j )           T1   ( p j , d i )}
        j


            S T 2 ( pi , d j )         s    t
                    L                           L
  s             {       T2   ( pi , d j )           T2   ( p j , d i )}
        j
                    U                           U
  t             {       T2   ( pi , d j )           T2   ( p j , d i )}
        j
3. Algorithm.
1.   Input the interval valued fuzzy soft sets (F,D)
     and (F,D)c over the sets S of symptoms, where
     D -set of diseases.

2.   Write the soft medical knowledge R1 and R2
     representing the relation matrices of the
     IVFSS (F,D) and (F,D)c respectively.
3.   Input the IVFSS (F1,S) over the set P of
     patients and write its relation matrix Q.

4.   Compute the relation matrices T1=Q R1 and
     T2=Q R2.

5.   Compute the diagnosis scores ST1 and ST2
6.   Find Sk= maxj { ST1 (pi , dj) ─ ST2 (pi,┐dj)}.

      Then we conclude that the patient          pi is
       suffering from the disease dk.
4. Case Study.
 Patients   - p1, p2 and p3.

 Symptoms (S) - Temperature, Headache, Cough
 and Stomach problem

 S={ e1,e2,e3,e4}   as universal set.

D   ={d1,d2}.
     d1 - viral fever, and
     d2 - malaria.
Suppose that,
F(d1) ={ 〈e1, [0.7,1]〉, 〈e2, [0.1,0.4]〉,
          〈e3, [0.5,0.6]〉, 〈e4,[0.2,0.4]〉)        }.

F(d2) ={    〈e1,[0.6,0.9] 〉,   〈e2,[0.4,0.6] 〉,
            〈e3,[0.3,0.6] 〉,   〈e4,[0.8, 1] 〉     }.

 IVFSS    - (F,D) is a parameterized family
                                 ={ F(d1), F(d2) }.
 IVFSS - (F,D) can be represented by a relation
 matrix R1 - symptom-disease matrix- given by,



    R1          d1           d2
    e1     [0.7, 1.0 ]   [ 0.6, 0.9 ]
    e2     [0.1, 0.4 ]   [0.4, 0.6 ]
    e3     [0.5, 0.6 ]   [0.3, 0.6 ]
    e4     [0.2, 0.4 ]   [0.8, 1.0 ]
 TheIVFSS - (F, D)c also can be represented by
 a relation matrix R2, - non symptom-disease
 matrix, given by-



        R2       d1             d2
        e1   [0 , 0.3 ]    [ 0.1, 0.4 ]
        e2   [0.6, 0.9 ]   [0.4, 0.6 ]
        e3   [0.4, 0.5 ]   [0.4, 0.7 ]
        e4   [0.6, 0.8 ]   [0 , 0.2 ]
 We   take P = { p1, p2, p3} - universal set .
            S = { e1, e2, e3, e4} - parameters.

Suppose that,
F1(e1)={〈p1, [.6, .9]〉, 〈p2, [.3,.5]〉,〈p3, [.6,.8]〉},

F1(e2)={ 〈p1, [.3,.5] 〉, 〈p2, [.3,.7] 〉, 〈p3, [.2,.6] 〉},

F1(e3)={〈p1, [.8, 1]〉, 〈p2, [.2,.4]〉,〈p3, [.5,.7]〉} and

F1(e4)={〈p1, [.6,.9] 〉,〈p2, [.3,.5] 〉, 〈p3, [.2,.5] 〉},
 IVFSS   - (F1,S) is a parameterized family
    ={ F1(e1), F1(e2), F1(e3), F1(e4) }.



             gives a collection of approximate
 description of the patient-symptoms in the
 hospital.
 (F1,S) - represents a relation a relation matrix
Q - patient-symptom matrix - given by;



Q    e1         e2           e3         e4
p1   [0.6, 0.9] [0.3, 0.5]   [0.8, 1] [0.6, 0.9]
p2   [0.3, 0.5] [0.3, 0.7]   [0.2, 0.4] [0.3, 0.5]
p3   [0.6, 0.8] [0.2, 0.6]   [0.5, 0.7] [0.2, 0.5]
 Combining   the relation matrices R1 and R2
 separately with Q. we get,

      T1=Q o R1 - patient-disease matrix.

      T2=Q o R2 - patient-non disease -
                                    matrix.
T1   d1         d2
p1   [0.1 ,0.9] [0.3 ,0.9]
p2   [0.1 ,0.5] [0.2 ,0.6]
p3   [0.1 ,0.8] [0.2 ,0.8]


                     T2      d1        d2
                     p1      [0 , 0.8] [0 , 0.7]
                     p2      [0 , 0.7] [0 , 0.6]
                     p3      [0 , 0.6] [0 , 0.7]
Now we calculate,

           ST1-ST2     d1     d2
           p1          0.2    0.6
           p2          -0.7   -0.4
           p3          0.5    -0.1

The patient p3 is suffering from the disease d1.

 Patients p1 and p2 are both suffering from
                                       disease d2.
References
1.   Chetia.B, Das.P.K, An Application of Interval-
     Valued Fuzzy Soft Sets in Medical
     Diagnosis, Int. J. Contemp. Math. Sciences, Vol.
     5, 2010, no. 38, 1887 - 1894

2.   De S.K, Biswas R, and Roy A.R, An application
     of intuitionistic fuzzy sets in medical
     diagnosis,       Fuzzy       Sets        and
     Systems,117(2001), 209-213.

3.   Maji PK, Biswas R and Roy A.R, Fuzzy Soft
     Sets, The Journal of Fuzzy    Mathematics
4.   Molodtsov D, Soft Set Theory-First
     Results, Computers and Mathematics with
     Application, 37(1999), 19-31.

5.   Roy MK, Biswas R, I-V fuzzy relations and
     Sanchez’s     approach   for      medical
     diagnosis,      Fuzzy     Sets        and
     Systems,47(1992),35-38.

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  • 1. AN APPLICATION OF INTERVAL- VALUED FUZZY SOFT SETS IN MEDICAL DIAGNOSIS Guide:Dr. Sunil Jacob John Jobish VD M090054MA
  • 2. Contents. 1. Preliminaries. 2. Application of interval valued fuzzy soft set in medical diagnosis. 3. Algorithm. 4. Case Study.
  • 4.  Definition 1.1[3]: Let U - initial universe set E - set of parameters. P (U) - power set of U. and, A - non-empty subset of E. A pair (F, A) is called a soft set over U, where F is a mapping given by F: A P (U).
  • 5.  Example 1.1; Let U={c1,c2,c3} - set of three cars. E ={costly(e1), metallic color (e2), cheap (e3)} - set of parameters. A={e1,e2} ⊂ E. Then; (F,A)={F(e1)={c1,c2,c3},F(e2)={c1,c3}} “ attractiveness of the cars” which Mr. X is going to buy .
  • 6.  Definition 1.2[3]: Let U - universal set, E - set of parameters and A ⊂ E. Let F (U) - set of all fuzzy subsets of U. Then a pair (F,A) is called fuzzy soft set over U, where F :A F (U).
  • 7.  Example 1.2; Let U = {c1,c2,c3} - set of three cars. E ={costly(e1),metallic color(e2) , getup (e3)} - set of parameters. A={e1,e2 } ⊂ E. Then; (G,A) = { G(e1)={c1/.6, c2/.4, c3/.3}, G(e2)={c1/.5, c2/.7, c3/.8} }. - fuzzy soft set over U. Describes the “ attractiveness of the cars” which Mr. S want.
  • 8. .  Definition 1.3[3]: An interval-valued fuzzy sets X on the universe U is a mapping such that; X : U → Int ([0,1]). where; Int ([0,1]) - all closed sub-intervals of [0,1]. The set of all interval-valued fuzzy sets on U is denoted by F (U).
  • 9.  If, ˆ ~ X F (U ), x U L U x ( x) ˆ [ ˆ x ( x), ˆ x ( x)] T hedegree of membership- of an element xto X L ˆ x ( x) lower degree of membership x toX U ˆ x ( x) upper degree of membership x toX L U 0 ˆ x ( x) ˆ x ( x) 1.
  • 10. ˆ ˆ ~  Let X , Y F ( U ). Then, Union ˆ ˆ of X and Y , denoted by, ˆ X  Y ˆ is given by - ( x ) sup [ ( x) , ( x )] X  Yˆ ˆ ˆ x ˆ y L L [ sup ( ( x), ( x)), ˆ x ˆ y U U sup ( ( x), ˆ y ( x ) ) ]. ˆ x
  • 11. ˆ ˆ ~ Let X , Y F ( U ). Then, ˆ ˆ Intersecti on of X and Y , denoted by, ˆ X  Y ˆ is given by - ( x ) inf [ ( x) , ( x)] X  Yˆ ˆ ˆ x ˆ y [ inf ( L ( x), L ( x)), ˆ x ˆ y inf ( U ( x ) , U ( x ) ) ]. xˆ ˆ y
  • 12. ˆ ˆ ~ Let X, Y F ( U ). Then, comlement of ˆ X denoted ˆ c, by X and is given by - (x) 1- ( x) . ˆ Xc ˆ x [1 - U ( x ) , 1 - L ( x ) ) ]. ˆ x ˆ y
  • 13.  Definition 1.7 [4]: Let U universal set. E set of parameters. and A ⊂E. ~ set of all interval-valued fuzzy sets on F (U ) U. Then a pair (F, A) is called interval-valued fuzzy soft set over U. ~ where F : A F (U ).
  • 14.  Definition 1.8[5]: The complement of a interval valued fuzzy soft set (F,A) is, (F,A)C = (FC,¬A), where ∀α ∈ A ,¬α = not α . FC: ¬A F ( U ). FC(β ) = (F ( ¬β ))C , ∀β ∈ ¬A
  • 15.  Example2.3: Let U={c1,c2,c3} set of three cars. E ={costly(e1), grey color(e2),mileage (e3)}, set of parameters. A={e1,e2} ⊂ E. Then, (G,A) = { G(e1)=〈c1,[.6,.9]〉,〈c2,[.4,.6]〉,〈c3,[.3,.5]〉, G(e2)= 〈c1,[.5,.7]〉, 〈c2,[.7,.9]〉 〈c3,[.6,.9]〉 } “ attractiveness of the cars” which Mr. X want.
  • 16.  Example 2.4: In example 2.3, (G,A)C = { G(¬e1)=〈c1,[0.1,0.4]〉, 〈c2,[0.4,0.6]〉, 〈c3,[0.5,0.7]〉, G(¬e2)=〈c1,[0.3,0.5]〉, 〈c2,[0.1,0.3]〉 〈c3,[0.1,0.4]〉 }.
  • 17. 2. Application – in medical diagnosis.
  • 18. S - Symptoms, D – Diseases, and P - Patients.  Construct an I-V fuzzy soft set (F,D) over S ~ F:D→ F ( S ).  A relation matrix say, R1 - symptom-disease matrix- constructed from (F,D).  Its complement (F,D)c gives R2 - non symptom-disease matrix.  We construct another I-V fuzzy soft set (F1,S) ~ over P, F1:S→ F ( P).
  • 19.  We construct another I-V fuzzy soft set (F1,S) ~ over P, F1:S→ F ( P).  Relation matrix Q - patient-symptom matrix- from (F1,S). Then matrices,  T1=Q R1 - symptom-patient matrix, and  T2= Q R2 - non symptom-patient matrix.
  • 20. The membership values are calculated by, T1 ( pi , d k ) [a, b] L L a inf { Q ( pi , e j ) R1 (e j , d k , )}, j U b sup { U Q ( pi , e j ) R1 (e j , d k , )} j T2 ( pi , d k ) [ x, y ] L L x inf { Q ( pi , e j ) R2 (e j , d k , )}, j U y sup { U Q ( pi , e j ) R2 (e j , d k , )} j
  • 21. The membership values are calculated by, S T1 ( pi , d j ) p q L L p { T1 ( pi , d j ) T1 ( p j , d i )} j U U q { T1 ( pi , d j ) T1 ( p j , d i )} j S T 2 ( pi , d j ) s t L L s { T2 ( pi , d j ) T2 ( p j , d i )} j U U t { T2 ( pi , d j ) T2 ( p j , d i )} j
  • 23. 1. Input the interval valued fuzzy soft sets (F,D) and (F,D)c over the sets S of symptoms, where D -set of diseases. 2. Write the soft medical knowledge R1 and R2 representing the relation matrices of the IVFSS (F,D) and (F,D)c respectively.
  • 24. 3. Input the IVFSS (F1,S) over the set P of patients and write its relation matrix Q. 4. Compute the relation matrices T1=Q R1 and T2=Q R2. 5. Compute the diagnosis scores ST1 and ST2
  • 25. 6. Find Sk= maxj { ST1 (pi , dj) ─ ST2 (pi,┐dj)}. Then we conclude that the patient pi is suffering from the disease dk.
  • 27.  Patients - p1, p2 and p3.  Symptoms (S) - Temperature, Headache, Cough and Stomach problem  S={ e1,e2,e3,e4} as universal set. D ={d1,d2}. d1 - viral fever, and d2 - malaria.
  • 28. Suppose that, F(d1) ={ 〈e1, [0.7,1]〉, 〈e2, [0.1,0.4]〉, 〈e3, [0.5,0.6]〉, 〈e4,[0.2,0.4]〉) }. F(d2) ={ 〈e1,[0.6,0.9] 〉, 〈e2,[0.4,0.6] 〉, 〈e3,[0.3,0.6] 〉, 〈e4,[0.8, 1] 〉 }.  IVFSS - (F,D) is a parameterized family ={ F(d1), F(d2) }.
  • 29.  IVFSS - (F,D) can be represented by a relation matrix R1 - symptom-disease matrix- given by, R1 d1 d2 e1 [0.7, 1.0 ] [ 0.6, 0.9 ] e2 [0.1, 0.4 ] [0.4, 0.6 ] e3 [0.5, 0.6 ] [0.3, 0.6 ] e4 [0.2, 0.4 ] [0.8, 1.0 ]
  • 30.  TheIVFSS - (F, D)c also can be represented by a relation matrix R2, - non symptom-disease matrix, given by- R2 d1 d2 e1 [0 , 0.3 ] [ 0.1, 0.4 ] e2 [0.6, 0.9 ] [0.4, 0.6 ] e3 [0.4, 0.5 ] [0.4, 0.7 ] e4 [0.6, 0.8 ] [0 , 0.2 ]
  • 31.  We take P = { p1, p2, p3} - universal set . S = { e1, e2, e3, e4} - parameters. Suppose that, F1(e1)={〈p1, [.6, .9]〉, 〈p2, [.3,.5]〉,〈p3, [.6,.8]〉}, F1(e2)={ 〈p1, [.3,.5] 〉, 〈p2, [.3,.7] 〉, 〈p3, [.2,.6] 〉}, F1(e3)={〈p1, [.8, 1]〉, 〈p2, [.2,.4]〉,〈p3, [.5,.7]〉} and F1(e4)={〈p1, [.6,.9] 〉,〈p2, [.3,.5] 〉, 〈p3, [.2,.5] 〉},
  • 32.  IVFSS - (F1,S) is a parameterized family ={ F1(e1), F1(e2), F1(e3), F1(e4) }. gives a collection of approximate description of the patient-symptoms in the hospital.
  • 33.  (F1,S) - represents a relation a relation matrix Q - patient-symptom matrix - given by; Q e1 e2 e3 e4 p1 [0.6, 0.9] [0.3, 0.5] [0.8, 1] [0.6, 0.9] p2 [0.3, 0.5] [0.3, 0.7] [0.2, 0.4] [0.3, 0.5] p3 [0.6, 0.8] [0.2, 0.6] [0.5, 0.7] [0.2, 0.5]
  • 34.  Combining the relation matrices R1 and R2 separately with Q. we get, T1=Q o R1 - patient-disease matrix. T2=Q o R2 - patient-non disease - matrix.
  • 35. T1 d1 d2 p1 [0.1 ,0.9] [0.3 ,0.9] p2 [0.1 ,0.5] [0.2 ,0.6] p3 [0.1 ,0.8] [0.2 ,0.8] T2 d1 d2 p1 [0 , 0.8] [0 , 0.7] p2 [0 , 0.7] [0 , 0.6] p3 [0 , 0.6] [0 , 0.7]
  • 36. Now we calculate, ST1-ST2 d1 d2 p1 0.2 0.6 p2 -0.7 -0.4 p3 0.5 -0.1 The patient p3 is suffering from the disease d1.  Patients p1 and p2 are both suffering from disease d2.
  • 37. References 1. Chetia.B, Das.P.K, An Application of Interval- Valued Fuzzy Soft Sets in Medical Diagnosis, Int. J. Contemp. Math. Sciences, Vol. 5, 2010, no. 38, 1887 - 1894 2. De S.K, Biswas R, and Roy A.R, An application of intuitionistic fuzzy sets in medical diagnosis, Fuzzy Sets and Systems,117(2001), 209-213. 3. Maji PK, Biswas R and Roy A.R, Fuzzy Soft Sets, The Journal of Fuzzy Mathematics
  • 38. 4. Molodtsov D, Soft Set Theory-First Results, Computers and Mathematics with Application, 37(1999), 19-31. 5. Roy MK, Biswas R, I-V fuzzy relations and Sanchez’s approach for medical diagnosis, Fuzzy Sets and Systems,47(1992),35-38.