Selective reporting and misrepresentation of data can lead to false conclusions and flawed decision making. Selective reporting involves intentionally presenting only information that supports a viewpoint while ignoring contradictory information. Misrepresentation distorts data to create a false impression. Both can occur through publication bias, outcome reporting bias, data dredging, spin, selective citation, data falsification, cherry-picking, manipulation, misinterpretation, and omission. Researchers should ensure transparency, present all relevant data, use appropriate statistical methods, verify sources, obtain independent review, follow ethical standards, and acknowledge limitations to avoid these issues.