Global warming and ozone depletion are caused by human activities like the release of greenhouse gases and chlorofluorocarbons. Greenhouse gases trap heat in the atmosphere, causing the surface and lower atmosphere to warm. This warming affects people through rising sea levels, increased tropical diseases, and dehydration. Ozone depletion occurs when chlorine atoms destroy ozone molecules in the ozone layer, allowing more ultraviolet radiation to reach the Earth's surface and increasing health risks like cataracts. International agreements like the Montreal Protocol aim to reduce ozone-depleting substances to mitigate these issues.