Nowerdays the battle of open versus closed is replaced with more complex debates, which are, unfortunately, a bit boring for many researchers. What does that mean for the spread of the science 2.0, the open and the citizen science movement?
Dispense Assist 2013 FEMA Region VII Medical ConferenceLiz Ticer
Want to know more about mass dispensing? This presentation was provided at the 2013 FEMA Region VII Medical Conference in Kansas City. It is an update/overview of the changes to Dispense Assist created by Johnson County Dept. of Health and Environment. www.dispenseassist.com
Get Your Message to the Masses: Social Media and Mass Antibiotic Dispensing C...auntiealli
Communicating during emergencies can be difficult, and large-scale emergencies can pose more expansive challenges when it comes to communicating public information. This session teaches participants how to harness social media tools for a mass antibiotic dispensing campaign where the public will need to go to a point of dispensing site to receive life-saving medicine. In addition, participants will learn the advantages of social media tools and how to develop a message strategy for using these tools. Social media efforts on public health topics are used to illustrate best practices.
H1N1 Preparedness Update by John R. Finnegan, Jr.Mark Engebretson
John Finnegan's presentation at the Sept. 10, 2009 H1N1: Lessons from the Southern Hemisphere and Minnesota's Preparedness at the University of Minnesota.
Dispense Assist 2013 FEMA Region VII Medical ConferenceLiz Ticer
Want to know more about mass dispensing? This presentation was provided at the 2013 FEMA Region VII Medical Conference in Kansas City. It is an update/overview of the changes to Dispense Assist created by Johnson County Dept. of Health and Environment. www.dispenseassist.com
Get Your Message to the Masses: Social Media and Mass Antibiotic Dispensing C...auntiealli
Communicating during emergencies can be difficult, and large-scale emergencies can pose more expansive challenges when it comes to communicating public information. This session teaches participants how to harness social media tools for a mass antibiotic dispensing campaign where the public will need to go to a point of dispensing site to receive life-saving medicine. In addition, participants will learn the advantages of social media tools and how to develop a message strategy for using these tools. Social media efforts on public health topics are used to illustrate best practices.
H1N1 Preparedness Update by John R. Finnegan, Jr.Mark Engebretson
John Finnegan's presentation at the Sept. 10, 2009 H1N1: Lessons from the Southern Hemisphere and Minnesota's Preparedness at the University of Minnesota.
What can we obtain if we merge the ideas of "Open Innovation", "Collaborative Innovation Network" and, why not, "crowdsourcing"? The results are virtual environments, opened to everybody, aimed to create innovation throught e-collaboration tools and methods. The presentation analyze two case studies and lead to the definition of Collaborative Knowledge environment
a mash up of ideas, notes and resources to help my lovely but disorganised bunch of A2 Media Studies students. bits borrowed from here and there - use how you wish.
Slides about LiquidPub project, presented at the 2nd Snow Workshop
http://wiki.liquidpub.org/mediawiki/index.php/Second_Workshop_on_Scientific_Knowledge_Creation%2C_Dissemination%2C_and_Evaluation
This slideshow identifies the problem of copyright imbalance and addresses where it is possible to effect change that broadens the opportunities for new creators who use existing copyrighted material, such as people making remixes, mashups, slideshows, and other works.
Glyn Moody: The great prize: open innovationglynmoody
talk given at European Parliament, 31 May. Details here: http://www.greenmediabox.eu/archive/2011/05/31/innovation/ and http://blogs.computerworlduk.com/open-enterprise/2011/06/the-great-prize-innovating-without-monopolies/index.htm
For decades, scientific journals were the only way to communicate new research findings. Up until today, very little has changed in that respect. The overwhelming majority of all scientific journals still functions as they did in the times when there was no Internet, no social networks or crowd-based knowledge platforms. Is this form of dissemination of research findings still suitable in the 21st century?
Slides of a plenary talk by Alexander Grossmann presented at Research Center Julich, Germany on Dec 21, 2016.
TelaSocial Presentation and Lessons Learned with the Pilot Case at ICMC-USPMarcio
This presentation covers the TelaSocial project, how it got started within the ICMC-USP community, part of University of Sao Paulo. It covers the open-based goals of the project and specific scenarios related to the pilot program at the ICMC, the Institute of Mathematics and Computer Science in Sao Carlos, Brazil. While the presentation covers the pilot case the messages within this documentation does not represent messages from ICMC. TelaSocial is a social-aware Web-based solution for kiosks. It uses an open model and aims for display-based system that does not get data from traditional broadcast. Instead, it uses the Web and promotes participation for public spaces. The project started in Brazil and we are looking for partners to move on in the direction of open education and to help communities with a participatory solution.
What can we obtain if we merge the ideas of "Open Innovation", "Collaborative Innovation Network" and, why not, "crowdsourcing"? The results are virtual environments, opened to everybody, aimed to create innovation throught e-collaboration tools and methods. The presentation analyze two case studies and lead to the definition of Collaborative Knowledge environment
a mash up of ideas, notes and resources to help my lovely but disorganised bunch of A2 Media Studies students. bits borrowed from here and there - use how you wish.
Slides about LiquidPub project, presented at the 2nd Snow Workshop
http://wiki.liquidpub.org/mediawiki/index.php/Second_Workshop_on_Scientific_Knowledge_Creation%2C_Dissemination%2C_and_Evaluation
This slideshow identifies the problem of copyright imbalance and addresses where it is possible to effect change that broadens the opportunities for new creators who use existing copyrighted material, such as people making remixes, mashups, slideshows, and other works.
Glyn Moody: The great prize: open innovationglynmoody
talk given at European Parliament, 31 May. Details here: http://www.greenmediabox.eu/archive/2011/05/31/innovation/ and http://blogs.computerworlduk.com/open-enterprise/2011/06/the-great-prize-innovating-without-monopolies/index.htm
For decades, scientific journals were the only way to communicate new research findings. Up until today, very little has changed in that respect. The overwhelming majority of all scientific journals still functions as they did in the times when there was no Internet, no social networks or crowd-based knowledge platforms. Is this form of dissemination of research findings still suitable in the 21st century?
Slides of a plenary talk by Alexander Grossmann presented at Research Center Julich, Germany on Dec 21, 2016.
TelaSocial Presentation and Lessons Learned with the Pilot Case at ICMC-USPMarcio
This presentation covers the TelaSocial project, how it got started within the ICMC-USP community, part of University of Sao Paulo. It covers the open-based goals of the project and specific scenarios related to the pilot program at the ICMC, the Institute of Mathematics and Computer Science in Sao Carlos, Brazil. While the presentation covers the pilot case the messages within this documentation does not represent messages from ICMC. TelaSocial is a social-aware Web-based solution for kiosks. It uses an open model and aims for display-based system that does not get data from traditional broadcast. Instead, it uses the Web and promotes participation for public spaces. The project started in Brazil and we are looking for partners to move on in the direction of open education and to help communities with a participatory solution.
Offenheit als Grundlage für gesellschaftliche Entwicklungen und Treiber für d...Christian Heise
Wir brauchen mehr Experimente mit Offenheit in Wissenschaft, Bildung und Forschung! Wir müssen aber dringend daran arbeiten die digitale Transformation der wissenschaftlichen Arbeitswelt und der Alltagsumgebung dafür zu nutzen Offenheit von Wissen nach gesellschaftlichen Maßstäben auch in der Wissenschaft zu verhandeln. Dieser Prozess und die Förderung von Experimenten für neue Formen der wissenschaftlichen Kommunikation sind dringend notwendig, damit Wissenschaft, Forschung und Bildung wichtige Impulsgeber für gesellschaftliche Entwicklungen bleiben. Am Beispiel meiner offenen Doktorarbeit (http://offene-doktorarbeit.de/) und der Erarbeitung von Handlungsempfehlungen für das offene Verfassen wissenschaftlicher (Qualifikations- )Arbeiten möchte ich einen ersten praktischen Beitrag zu der Debatte über Neugestaltung wissenschaftlicher Kommunikation leisten.
Disputation: Von Open Access zu Open Science: Zum Wandel digitaler Kulturen d...Christian Heise
Präsentation der mündlichen Verteidigung der Doktorarbeit mit dem Titel: Von Open Access zu Open Science: Zum Wandel digitaler Kulturen der wissenschaftlichen Kommunikation am Promotionskolleg "Wissenskulturen / Digitale Medien" der Leuphana Universität in Lüneburg.
We try to use the agile software development methodology "Scrum" to organize the university course "Media Production III" in the Digital media Bachelor’s program (MDM) of Hamburg Media School and Leuphana University.
Vorstellung "Von Open Access zu Open Science" im Kolloquium des Kollegs "Wis...Christian Heise
Vostellung und Besprechung des Promotionsvorhabens mit dem Titel: "Von Open Access zu Open Science: Zum Wandel von wissenschaftlicher Kommunikation im Rahmen der Digitalisierung" an der Leuphana Universität 9.1.2015
Projektmanagement in vernetzten ForschungsprojektenChristian Heise
Der Arbeitsalltag von Forschenden ist zusehends von den Werkzeugen und technischen Möglichkeiten des Internets und einer kollaborativen Arbeitsweise geprägt. Dieser Vortrag entstand im Rahmen einer Lecture-Reihe der TIB Hannover, in der Nachwuchswissenschaftler(inn)en nützliche Tipps zum kollaborativen wissenschaftlichen Arbeiten mit dem Netz erhalten.
HybridDocs - A Digital Learning Environment based on FlashCardsChristian Heise
HybridDocs is a software prototype for transforming analog learning materials into a hybrid format. The prototype is based on the pedagogical concept of Sebastian Leitner. We build a tool for restructing the data and writing learning cards / flashcards. The process allows users to import and convert whole books/manuscipts to datasets and a sets of digital flashcards.
Open Data und investigativer Journalismus - Ergebnisse einer explorativen Bef...Christian Heise
Open-Data-Initiativen öffentlicher Einrichtungen verbreiten sich weltweit rasant. Als Treiber für den Drang nach mehr Transparenz und Offenheit wirken dabei einerseits wirtschaftspolitische, andererseits demokratietheoretische Potentiale. Doch ermöglichen Open-Data-Initiativen wirklich eine bessere Berichterstattung über Vorgänge und Prozesse in Politik und öffentlicher Verwaltung, und was unterscheidet diese Initiativen als Zugangsmöglichkeit zu öffentlichen Daten von dem Zugang über bestehende Informationsfreiheitsgesetze? Welchen Wert haben die veröffentlichten Datensätze letztendlich für die journalistische Arbeit und insbesondere die investigative Berichterstattung?
Die Rohdaten der Befragung sind unter https://zenodo.org/record/12252 abrufbar.
Open Access, Open Research, Open Data, Open Science, Open what? #gfm2013Christian Heise
Drawing from a quick overview of the recent discourses on Open Access, Open Research and Open Science we will challenge the all to often unspecific and generalized notion of "Openness". What does it mean to be open in contrast to being closed? On activist level the Open Knowledge Foundation proposed an 'Open Definition' which lists eleven criteria for openness. By discussing this definition we intend to outline some controversial issues in the current struggle for openness.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
The Bad News About the Good News: Openness has won
1. The Bad News About the
Good News: Openness has
won
Christian Heise, Centre for Digital Cultures / Open Knowledge Foundation DE e.V.
Barcamp Science 2.0, Hamburg, 24.03.15
ZBW – Deutsche Zentralbibliothek für Wirtschaftswissenschaften
8. Challenges:
- CC-BY vs CC-BY-NC/ND; Gold vs Green Open Access
Policy vs other Policies; Self-hosted vs Third party
services …
- never lose sight of our objective
Possible Approaches:
- open up the debate
- discuss regularly on issues about openness
- open access commissioner in scientific institutions
- open access policies at universities
10. Challenges:
- „openwashing“, assimilation, imprisonment and
enclosure of research (e.g. #BlockReadcube)
- legal loopholes / „hybrid OA“ (e.g. offering authors CC-
BY-NC for a fee, while giving themselves commercial use
license)
Possible Approaches:
- constant public fight against „openwashing“ and legal
loopholes
- let us start the critique of openness
- start a recognized clearing institution (labeling)
- always refer to criteria of the open definition
12. Challenges:
- „open“ and collaborative scientific work is still not
convenient
- reducing the manual effort
- solve right issues and misunderstandings / urban
legends
Possible Approaches:
- awards / hackdays / whatever dissemination
- build more and better tools and showcases
- enable your colleagues
13. 4. No way (yet) in gaining (high)
reputation via open scientific work
14. Challenges:
- development and acceptance of alternative metrics
- open reputation without loss of idea diversity
Possible Approaches:
- publish good stuff via open channels
- convince your colleagues to publish openly
- conquer the consequences of openness
16. Academics (we) have to decide now on:
A. to improve steady-state(just good news)
or
B. focus on a new scientific revolution? (good & bad news)
17. Sources/References:
A bevy of Japanese GameBoy carts (CC-BY-SA 2.0) by Bryan Ochalla
Taiko no Tatsujin DS manual page(s) (CC-BY-SA 2.0) by Bryan Ochalla
Our Collection (CC-BY-ND2.0) by wisekris
Guy with WII (CC-BY-ND 2.0) by Herman Yung
Ottawa Comiccon 2014: Game Boy (CC-BY-SA 2.0) by Pikawil
Gameboy Advance A-f-T-e-R-b-U-r-N-e-R (CC-BY 2.0) by Joey Mink
Nintendo Gameboy (CC-BY 2.0) by William Warby
Complete-in-box GameBoy (CC-BY-SA 2.0) by Bryan Ochalla
Further Links:
Open Knowledge Foundation Deutschland e.V.: http://www.okfn.de
Open Knowledge Definition: http://www.opendefinition.org
DE Open Science AG: http://okfn.de/open-science/
Ross Mounce - Show me the data!: http://rossmounce.co.uk/
Pawel Szczesny on „Science 2.0 - and now what?“: http://www.slideshare.net/freesci
Martin Weller on „Openness has won – now what?“: http://blogs.lse.ac.uk(...)openness-has-won-now-what/
Contact:
Twitter: @christianheise
Mail: christian.heise@okfn.de